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US5395504A Expired / Lapsed US ⏱️ 0.0 years remaining

Electrochemical measuring system with multizone sensors

Assignee: Asulab AG
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Filing: 1994-02-01
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Granted: 1995-03-07
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Expires: 2014-02-01
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Abstract

Abstract A small sensor for an electrochemical measuring system composed of a measuring apparatus (50) having an electronic circuit (60), a connecting device (64), a positioning and advancing device (56, 57) and an eliminating device (59, 53). The apparatus is adapted to receive the sensor (40), which has a plurality of active, successively disposable measuring zones (34). The sensor has applications in the quantitative analysis of glucose in the blood.

Inventors

  • 👤 Eric Saurer
  • 👤 Erik J. Frenkel
  • 👤 Jean-Paul Randin
  • 👤 Eric Hoffmann

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 16:09
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/4875; B; B01; B01L; B01L3/00; B01L3/50; B01L3/508; B01L3/5085; C; C12; C12Q; C12Q1/00; C12Q1/001; Y; Y10; Y10S; Y10S435/00; Y10S435/817

Claims Analysis

Total Claims: 31
Claim 1
Independent Claim 178 words
A sensor for use in an electrochemical measuring apparatus adapted to receive the sensor for carrying out at least two successive measurements of the same physicochemical characteristic or of a concentration of the same component present in a solution, an effluent or a fluid, said sensor comprising: a thin insulating support in the form of a strip, at least two current collectors of conducting material arranged on said strip and electrically insulated from each other, at least one insulating covering partially covering a surface of the strip and the current collectors to delimit at least one contact zone and at least two consecutive windows providing access to the current collectors, said current collectors constituting electrodes and said windows delimiting on the surface of the strip a plurality of open measuring zones each for receiving and holding a drop of said solution, effluent or fluid to provide on the surface of the sensor a plurality of active sequentially disposable measuring zones for carrying out said at least two measurements by introducing a single said sensor into said measuring apparatus.
Claim 2
Dependent Claim 178 words
A sensor for use in an electrochemical measuring apparatus adapted to receive the sensor for carrying out at least two successive measurements of the same physicochemical characteristic or of a concentration of the same component present in a solution, an effluent or a fluid, said sensor comprising: a thin insulating support in the form of a strip, at least two current collectors of conducting material arranged on said strip and electrically insulated from each other, at least one insulating covering partially covering a surface of the strip and the current collectors to delimit at least one contact zone and at least two consecutive windows providing access to the current collectors, said current collectors constituting electrodes and said windows delimiting on the surface of the strip a plurality of open measuring zones each for receiving and holding a drop of said solution, effluent or fluid to provide on the surface of the sensor a plurality of active sequentially disposable measuring zones for carrying out said at least two measurements by introducing a single said sensor into said measuring apparatus.
Claim 3
Dependent Claim 21 words
A sensor according to claim 1, wherein the current collectors are situated on the same side of the insulating support strip.
Claim 4
Dependent Claim 20 words
A sensor according to claim 1, wherein the current collectors are situated on opposite sides of the insulating support strip.
Claim 5
Dependent Claim 18 words
A sensor according to claim 1, wherein contact zones are situated at the extremities of the current collectors.
Claim 6
Dependent Claim 19 words
A sensor according to claim 1, wherein contact zones are located along the outside edges of the current collectors.
Claim 7
Dependent Claim 18 words
A sensor according to claim 1, wherein contact zones are situated in windows provided in the covering strip.
Claim 8
Dependent Claim 28 words
A sensor according to claim 1, wherein each of the current collectors comprises a thin-layer or thick-layer strip of conducting material deposited directly onto the thin insulating support.
Claim 9
Dependent Claim 19 words
A sensor according to claim 7, wherein the conducting material is gold, silver, platinum, nickel, palladium, titanium or carbon.
Claim 10
Dependent Claim 25 words
A sensor according to claim 1, wherein each of the current collectors comprises a coated film of conducting material laminated on the thin insulating support.
Claim 11
Dependent Claim 27 words
A sensor according to claim 1, wherein the insulating support strip is composed of a flexible material configured in the form of a bar or a roll.
Claim 12
Dependent Claim 14 words
A sensor according to claim 10, wherein the flexible material is a polyethylene terephthalate.
Claim 13
Dependent Claim 17 words
A sensor according to claim 1, wherein the insulating support strip is composed of a brittle material.
Claim 14
Dependent Claim 15 words
A sensor according to claim 12, wherein the brittle material is mica, glass or ceramic.
Claim 15
Dependent Claim 30 words
A sensor according to claim 1, wherein the insulating support strip also has positioning means comprising notches regularly spaced in the thickness of at least one edge of the strip.
Claim 16
Dependent Claim 34 words
A sensor according to claim 1, wherein the insulating support strip also has positioning and sectioning means comprising grooves regularly spaced in the surface of the strip opposite the surface having the measuring zones.
Claim 17
Dependent Claim 42 words
A sensor according to claim 1, wherein the current collectors are on opposite sides of the support strip, and the covering of the insulating support strip and the current collectors comprises coatings of unequal thickness on opposite sides of the support strip.
Claim 18
Dependent Claim 34 words
A sensor according to claim 1, wherein the thickness of the covering adjacent to the windows provided in the covering cooperate with the insulating support strip to delimit cavities capable of receiving a reagent.
Claim 19
Dependent Claim 35 words
A sensor according to claim 17, wherein the bases of the cavities are delimited by the insulating support strip and the windows provided in the covering acquire a cup-like shape by stamping or heat distortion.
Claim 20
Dependent Claim 32 words
A sensor according to claim 1, wherein one current collector is of platinum and constitutes a working electrode and the other current collector is of silver/silver chloride and constitutes a reference electrode.
Claim 21
Dependent Claim 28 words
A sensor according to claim 19, wherein the working electrode is covered by a reagent having at least one specific enzyme of a constituent present in the solution.
Claim 22
Dependent Claim 13 words
A sensor according to claim 20, wherein the reagent also has a mediator.
Claim 23
Dependent Claim 43 words
A sensor according to claim 21, wherein the mediator is a complex of a transition metal having ligands selected from the group consisting of bipyridine, terpyridine and phenantroline, at least one of said ligands being substituted by at least one electron donor group.
Claim 24
Dependent Claim 20 words
A sensor according to claim 20, wherein the specific enzyme is glucose oxidase to effect the quantitative analysis of glucose.
Claim 25
Dependent Claim 34 words
A sensor according to claim 1, wherein said strip has a substantially rectangular transverse cross section and a width comprising between 6 and 12 mm, and a thickness comprising between 0.05 and 0.5 mm.
Claim 26
Dependent Claim 131 words
A measuring apparatus in combination with a sensor according to claim 1, wherein the measuring apparatus comprises: a housing, an electronic circuit and an energy source situated inside said housing for imposing a variable or non-variable electric current or a variable or non-variable potential difference between contacts which receive the sensor, and for treating a resulting electrical signal and displaying a value representative of the characteristic or concentration measured, at least one opening provided in the housing and adapted to receive the sensor, means for connecting the sensor introduced into the opening of said housing electrically to the electronic circuit throughout the duration of a series of measurements, means for positioning and advancing the sensor inside the housing, and means for removing one measuring zone of the sensor after each measurement.
Claim 27
Dependent Claim 49 words
A measuring apparatus for receiving a sensor according to claim 25, wherein the positioning and advancing means comprises control means located on an outside part of the housing and continued inside the housing by a mechanism that cooperates with notches or grooves of the support strip of the sensor.
Claim 28
Dependent Claim 37 words
A measuring apparatus according to claim 26, wherein the control means is arranged so that a single manipulation of the control means causes displacement of the sensor to the extent necessary to effect the next successive measurement.
Claim 29
Dependent Claim 54 words
A measuring apparatus for receiving a sensor according to claim 25, wherein the removing means removes a used measuring zone and comprises a cutting blade cooperating with a device for bringing the blade into contact with the sensor, said device being fixed to a control organ located on an outer part of the housing.
Claim 30
Dependent Claim 32 words
A measuring apparatus for receiving a sensor according to claim 25, wherein the electronic circuit comprises a time base means for delivering a signal corresponding to the frequency required for the measurements.
Claim 31
Dependent Claim 21 words
A measuring apparatus for receiving a sensor according to claim 25, wherein the electronic circuit comprises a thermometer for temperature compensation.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1998-03-06 1998-09-05 1999-03-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2002-03-06 2002-09-05 2003-03-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2006-03-06 2006-09-05 2007-03-07 $7700.00 Window Closed / Lapsed

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