Patent US5276272A successfully refreshed from Google Patents.
Patent US5348551A successfully refreshed from Google Patents.
US5348551A
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Method for correcting refractive disorders
Assignee: Kerus Medical Systems
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Filing: 1993-03-23
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Granted: 1994-09-20
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Expires: 2013-03-23
Abstract
Abstract A method for changing the shape of the cornea of an eye to correct refractive disorders comprises employing laser radiation having a selected wavelength, beam pattern, and beam power profile, and employing this radiation for a selected time duration, wherein the wavelength, beam pattern, beam power profile and time duration are chosen to selectively kill or injure keratocytes and to avoid shrinking the collagen in a selected treatment volume of the cornea which has a posterior boundary which is at least 10% of the total stromal depth, and preferably between 50-90% of the stromal depth.
Inventors
- 👤 Kenneth G. Spears
- 👤 Gerald Horn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 21:58
CPC Classifications
A; A61; A61F; A61F9/00; A61F9/007; A61F9/008; A61F2009/00853; A61F2009/00861; A61F2009/00872; A61F2009/00878; A61F2009/00882
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
115 words
A method for changing the shape of a cornea having a central optical axis, comprising the steps of: positioning a laser to irradiate said cornea; and irradiating said cornea with a laser beam from said laser, said laser beam having a power density profile in a treatment pattern, said laser beam having a wavelength such that the absorption coefficient of said wavelength in water ranges from 5 cm -1 to 114 cm -1 , with an energy sufficient to and for a time sufficient to necrotize stromal keratocytes in a selected treatment volume without substantially shrinking collagen in said cornea, said treatment depth having a posterior boundary of at least 50% of the stromal depth.
Claim 2
Independent Claim
115 words
A method for changing the shape of a cornea having a central optical axis, comprising the steps of: positioning a laser to irradiate said cornea; and irradiating said cornea with a laser beam from said laser, said laser beam having a power density profile in a treatment pattern, said laser beam having a wavelength such that the absorption coefficient of said wavelength in water ranges from 5 cm -1 to 114 cm -1 , with an energy sufficient to and for a time sufficient to necrotize stromal keratocytes in a selected treatment volume without substantially shrinking collagen in said cornea, said treatment depth having a posterior boundary of at least 50% of the stromal depth.
Claim 3
Dependent Claim
23 words
The method of claim 1 wherein said selected treatment volume has a posterior boundary equal to the total stromal depth in said cornea.
Claim 4
Dependent Claim
28 words
The method of claim 1 wherein said selected treatment volume has a posterior boundary equal to from about 50% to 90% of the stromal depth in said cornea.
Claim 5
Dependent Claim
15 words
The method of claim 1 wherein said time is between about 1.5 to 15 seconds.
Claim 6
Dependent Claim
32 words
The method as recited in claim 1 including the step of directing said laser beam onto the cornea in multiple treatments over short time intervals between about 10 seconds and 1 hour.
Claim 7
Dependent Claim
19 words
The method as recited in claim 1 including the step of directing said laser beam onto the cornea continuously.
Claim 8
Dependent Claim
20 words
The method as recited in claim 1 including the step of directing said laser beam onto the cornea with modulation.
Claim 9
Dependent Claim
46 words
The method of claim 1 wherein the step of irradiating comprises irradiating with a laser beam having a center and a periphery such that the power density profile of said laser beam is higher near the periphery of said treatment pattern than near the center thereof.
Claim 10
Dependent Claim
50 words
The method of claim 1 wherein the irradiating step comprises irradiating with a laser beam having a power density profile which varies across said treatment pattern to create an approximately equal temperature profile across said treatment pattern at any given depth of said treatment volume during application of laser energy.
Claim 11
Dependent Claim
42 words
The method of claim 1 wherein the step of irradiating includes generating said treatment pattern as a substantially circular treatment region, having a diameter of between about 2 mm to 12 mm and centered on said central optical axis of said cornea.
Claim 12
Dependent Claim
76 words
The method of claim 1 wherein the step of irradiating includes generating said treatment pattern as a plurality of symmetrical, spaced apart, radial treatment sectors having a radial length of from about 1 mm to 6 mm, said radial sectors disposed about an untreated subtantially circular central region having a radius of between about zero to 4 mm, said radial sectors separated by untreated radial regions and centered on said central optical axis of said cornea.
Claim 13
Dependent Claim
90 words
The method of claim 1 wherein the step of irradiating includes generating said treatment pattern centered on said central optical axis of said cornea as a plurality of symmetrical, spaced apart, radial treatment sectors having a radial length of from about 1 mm to 6 mm disposed about a central substantially circular treatment region having a diameter of between about zero to 3 mm said radial treatment sectors separated from said circular treatment region by an untreated annular region having a radial width of from about 0.25 to 2 mm.
Claim 14
Dependent Claim
125 words
The method of claim 1 wherein the step of irradiating includes generating said treatment pattern centered on said central optical axis of said cornea as a plurality of concentric treatment annuli disposed about a substantially circular central treatment region having a radius of from about zero to 3 mm, a first treatment annuli having a radial width of from about 0.25 to 2 mm and separated from said central treatment region by a first untreated annular region having a radial width of from about 0.25 to 2 mm, a second treatment annuli having a radial width of from about 0.25 to 2 mm and separated from said first annuli by a second untreated region having a radial width of from about 0.25 to 2 mm.
Claim 15
Dependent Claim
79 words
The method of claim 1 wherein the step of irradiating in said treatment pattern includes irradiating a pair of radial treatment sectors located symmetrically on opposite sides of said central optical axis of said cornea, said radial treatment sectors having a radial length of from about 0.25 mm to 6 mm disposed about a central untreated region comprising a substantially circular region centered on said central optical axis and having a radius of from about zero to 6 mm.
Claim 16
Dependent Claim
66 words
The method of claim 1 wherein the step of irradiating in said treatment pattern includes irradiating a pair of substantially circular treatment zones located symmetrically on opposite sides of said central optical axis of said cornea, said circular treatment zones having diameters of from about 0.25 to 4 mm and whose centers lie on a circle having a radius of from about zero to 6 mm.
Claim 17
Dependent Claim
22 words
The method as recited in claim 1 in which the step of irradiating includes pumping a laser medium by a diode laser.
Claim 18
Dependent Claim
30 words
The method as recited in claim 1 including generating the laser beam with means including a laser medium containing Co +2 ions in an M g F 2 crystalline media.
Claim 19
Dependent Claim
22 words
The method as recited in claim 17 in which the step of irradiating includes pumping a laser medium by a diode laser.
Claim 20
Dependent Claim
14 words
The method of claim 1 including generating the laser beam from a diode laser.
Claim 21
Dependent Claim
39 words
The method as recited in claim 1 including generating the laser beam with means including a crystalline laser medium containing ions selected from the group consisting of Holmium +3 ions, Thulium +3 ions, Erbium +3 ions and mixtures thereof.
Claim 22
Dependent Claim
22 words
The method as recited in claim 20 in which the step of irradiating includes pumping a laser medium by a diode laser.
Claim 23
Dependent Claim
63 words
The method of claim 1 wherein the step of irradiating includes generating said treatment pattern centered on said central optical axis of said cornea as a first treatment annulus concentrically disposed about a substantially circular central untreated region having a radius of from about zero to 4 mm, said first treatment annulus having a radial width of from about 0.5 to 3 mm.
Claim 24
Dependent Claim
61 words
The method of claim 22 wherein generating said treatment pattern further includes generating a second treatment annulus concentrically disposed about said first treatment annulus, said second treatment annulus having a radial width of from about 0.5 to 2 mm and separated from said first annuli by an untreated annular region having a radial width of from about 0.25 to 2 mm.
References Cited (Backward Citations)
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| 3.5 Years (Year 4) | 1997-09-19 | 1998-03-21 | 1998-09-20 | $2000.00 | Window Closed / Lapsed |
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