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US5338512A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for oxygenation of a patient's blood

Assignee: Jostra Bentley Inc
•
Filing: 1993-03-02
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Granted: 1994-08-16
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Expires: 2013-03-02
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Abstract

Abstract A device including an integrally formed membrane oxygenator and heat exchange device positioned in a single housing. The device includes a thermally conductive body formed with a plurality of blood pathways on its surface, and a gas permeable membrane, or membranes positioned in the housing in substantial contact with the heat exchange body to cover or lie within a portion of each of the pathways. The membrane defines a gas pathway separate from the blood pathway through which a gas is directed. The blood is directed through the individual blood pathways. The device also includes various ports and passageways for delivering the blood to the individual channels, and for collecting and removing the blood from the device.

Inventors

  • 👤 Wilfred F. Mathewson
  • 👤 Richard L. Bringham
  • 👤 Philip L. Ritger
  • 👤 David L. Karshmer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 16:05
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1698; A61M1/1621; A61M1/1623; A61M1/1625; A61M1/1629; A61M1/36; A61M1/3621; A61M1/3623; B; B01; B01D; B01D63/00; B01D63/02; B01D63/033; B01D2313/00; B01D2313/10; B01D2313/105; B01D2313/12; B01D2313/125; B01D2313/22; B01D2313/221; Y; Y10; Y10S; Y10S128/00; Y10S128/03; Y10S261/00; Y10S261/28

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 125 words
A method of oxygenating a patient's blood, comprising the steps of providing a device comprising a thermally conductive core centrally disposed within a housing and having a heat exchange surface, the device further comprising a plurality of gas permeable membranes and a plurality of blood flow passageways, the plurality of blood flow passageways positioned parallel to the heat exchange surface and defined by the heat exchange surface and the plurality of gas permeable membranes, each of the plurality of gas permeable membranes having a hollow lumen; passing a gas through the hollow lumens by the plurality of gas permeable membranes; and passing a patient's blood through the device by simultaneously exposing the blood to the heat exchange surface and the plurality of gas permeable membranes.
Claim 2
Independent Claim 125 words
A method of oxygenating a patient's blood, comprising the steps of providing a device comprising a thermally conductive core centrally disposed within a housing and having a heat exchange surface, the device further comprising a plurality of gas permeable membranes and a plurality of blood flow passageways, the plurality of blood flow passageways positioned parallel to the heat exchange surface and defined by the heat exchange surface and the plurality of gas permeable membranes, each of the plurality of gas permeable membranes having a hollow lumen; passing a gas through the hollow lumens by the plurality of gas permeable membranes; and passing a patient's blood through the device by simultaneously exposing the blood to the heat exchange surface and the plurality of gas permeable membranes.
Claim 3
Dependent Claim 45 words
The method of claim 1, wherein the step of passing a patient's blood includes the step of: directing the patient's blood through the plurality of blood flow passageways by simultaneously exposing the blood to the heat exchange surface and the plurality of gas permeable membranes.
Claim 4
Dependent Claim 25 words
The method of claim 1, wherein the step of passing a patient's blood includes the step of: collecting and returning the blood to the patient.
Claim 5
Dependent Claim 18 words
The method of claim 1, wherein the heat exchange surface comprises an inside surface and an outside surface.
Claim 6
Dependent Claim 24 words
The method of claim 4, further comprising the step of directing a heat exchange fluid against the inside surface of the heat exchange surface.
Claim 7
Dependent Claim 30 words
The method of claim 5, wherein the plurality of blood flow passageways is defined by the plurality of gas permeable membranes and the outside surface of the heat exchange surface.
Claim 8
Dependent Claim 49 words
The method of claim 6, wherein the step of passing a patient's blood includes the step of: directing the patient's blood through the plurality of blood flow passageways by simultaneously exposing the blood to the outside surface of the heat exchange surface and the plurality of gas permeable membranes.
Claim 9
Independent Claim 174 words
A method of oxygenating a patient's blood, comprising the steps of: (a) providing a blood oxygenator comprising a housing having a blood inlet and a blood outlet; a cylindrically shaped bellows mounted within the housing, the bellows having an outer wall with a plurality of pleats formed therefrom, with a plurality of blood receiving channels being defined between adjacently positioned pleats, and wherein the outer wall of the bellows defines a heat exchange surface; a plurality of gas permeable hollow fiber membranes positioned in each of the blood receiving channels, each of the hollow fiber membranes having a hollow lumen; and a plurality of circumferential blood flow paths defined between the outer wall of the bellows and the plurality of hollow fiber membranes; (b) directing blood from a patient into the blood inlet and into the plurality of blood flow paths; and (c) passing a gas through the hollow lumen of each hollow fiber membrane; (d) simultaneously exposing the blood to the outer wall of the bellows and the plurality of gas permeable membranes.
Claim 10
Independent Claim 174 words
A method of oxygenating a patient's blood, comprising the steps of: (a) providing a blood oxygenator comprising a housing having a blood inlet and a blood outlet; a cylindrically shaped bellows mounted within the housing, the bellows having an outer wall with a plurality of pleats formed therefrom, with a plurality of blood receiving channels being defined between adjacently positioned pleats, and wherein the outer wall of the bellows defines a heat exchange surface; a plurality of gas permeable hollow fiber membranes positioned in each of the blood receiving channels, each of the hollow fiber membranes having a hollow lumen; and a plurality of circumferential blood flow paths defined between the outer wall of the bellows and the plurality of hollow fiber membranes; (b) directing blood from a patient into the blood inlet and into the plurality of blood flow paths; and (c) passing a gas through the hollow lumen of each hollow fiber membrane; (d) simultaneously exposing the blood to the outer wall of the bellows and the plurality of gas permeable membranes.
Claim 11
Dependent Claim 28 words
The method of claim 8, further comprising the step of: (e) upon substantially filling the plurality of blood flow paths, directing the blood through the hollow fiber membranes.
Claim 12
Dependent Claim 23 words
The method of claim 9, further comprising the step of: (f) collecting and returning oxygenated blood to the patient through the blood outlet.
Claim 13
Independent Claim 173 words
A method of oxygenating a patient's blood, comprising the steps of: (a) providing a blood oxygenator comprising a housing having a blood inlet and a blood outlet; a cylindrically shaped bellows mounted within the housing, the bellows having an outer wall with a plurality of pleats formed therefrom, with a plurality of blood receiving channels being defined between adjacently positioned pleats; a plurality of gas permeable hollow fiber membranes positioned in each of the blood receiving channels, each of the hollow fiber membranes having a hollow lumen; and a plurality of circumferential blood flow paths defined between the outer wall of the bellows and the plurality of hollow fiber membranes; (b) directing blood from a patient into the blood inlet and into the plurality of blood flow paths; (c) passing a gas through the hollow lumen of each hollow fiber membrane; (d) upon substantially filling the plurality of blood flow paths, directing the blood through the hollow fiber membranes; and (e) collecting and returning oxygenated blood to the patient through the blood outlet.
Claim 14
Independent Claim 173 words
A method of oxygenating a patient's blood, comprising the steps of: (a) providing a blood oxygenator comprising a housing having a blood inlet and a blood outlet; a cylindrically shaped bellows mounted within the housing, the bellows having an outer wall with a plurality of pleats formed therefrom, with a plurality of blood receiving channels being defined between adjacently positioned pleats; a plurality of gas permeable hollow fiber membranes positioned in each of the blood receiving channels, each of the hollow fiber membranes having a hollow lumen; and a plurality of circumferential blood flow paths defined between the outer wall of the bellows and the plurality of hollow fiber membranes; (b) directing blood from a patient into the blood inlet and into the plurality of blood flow paths; (c) passing a gas through the hollow lumen of each hollow fiber membrane; (d) upon substantially filling the plurality of blood flow paths, directing the blood through the hollow fiber membranes; and (e) collecting and returning oxygenated blood to the patient through the blood outlet.

References Cited (Backward Citations)

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US4902476A Cited
US4781889A Cited
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US4645645A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-08-15 1998-02-14 1998-08-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-08-15 2002-02-14 2002-08-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-08-15 2006-02-14 2006-08-16 $7700.00 Window Closed / Lapsed

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