US5120501A
Expired / Lapsed
US
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Integrated membrane blood oxygenator/heat exchanger
Assignee: Jostra Bentley Inc
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Filing: 1988-10-20
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Granted: 1992-06-09
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Expires: 2008-10-20
Abstract
Abstract A device including an integrally formed membrane oxygenator and heat exchange device positioned in a single housing. The device includes a thermally conductive body formed with a plurality of blood pathways on its surface, and a gas permeable membrane, or membranes positioned in the housing in substantial contact with the heat exchange body to cover or lie within a portion of each of the pathways. The membrane defines a gas pathway separate from the blood pathway through which a gas is directed. The blood is directed through the individual blood pathways. The device also includes various ports and passageways for delivering the blood to the individual channels, and for collecting and removing the blood from the device.
Inventors
- 👤 Wifred F. Mathewson
- 👤 Richard L. Bringham
- 👤 Philip L. Ritger
- 👤 David Karshmer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:08
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1698; A61M1/1621; A61M1/1623; A61M1/1625; A61M1/1629; A61M1/36; A61M1/3621; A61M1/3623; B; B01; B01D; B01D63/00; B01D63/02; B01D63/033; B01D2313/00; B01D2313/10; B01D2313/105; B01D2313/12; B01D2313/125; B01D2313/22; B01D2313/221; Y; Y10; Y10S; Y10S128/00; Y10S128/03; Y10S261/00; Y10S261/28
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
211 words
A blood oxygenator and heat exchange device comprising: a housing defining at least a first internal chamber; at least a first thermally conductive core positioned inside said at least a first housing internal chamber, said at least a first core being formed with an internal region through which a heat exchange fluid is directed, said at least a first core further being formed with at least a first external surface, said at least a first external surface being formed with a plurality of separate, adjacently positioned parallel blood receiving channels; individual gas permeable membranes arranged in each of said channels, each of said membranes defining separate gas flow pathways which are open at opposite ends of said membranes; said housing further including at least a first gas manifold which is formed with at least two gas channels, each of said at least two gas channels being formed to communicate with selective ends of said membranes, said at lest two channels further being formed to fluidly communicate to ports which gas is selectively introduced or removed from said at least two gas channels; and at least a first blood manifold means mounted in said housing and adjacent to said at least a first core for delivering blood to said blood receiving channels.
Claim 2
Dependent Claim
211 words
A blood oxygenator and heat exchange device comprising: a housing defining at least a first internal chamber; at least a first thermally conductive core positioned inside said at least a first housing internal chamber, said at least a first core being formed with an internal region through which a heat exchange fluid is directed, said at least a first core further being formed with at least a first external surface, said at least a first external surface being formed with a plurality of separate, adjacently positioned parallel blood receiving channels; individual gas permeable membranes arranged in each of said channels, each of said membranes defining separate gas flow pathways which are open at opposite ends of said membranes; said housing further including at least a first gas manifold which is formed with at least two gas channels, each of said at least two gas channels being formed to communicate with selective ends of said membranes, said at lest two channels further being formed to fluidly communicate to ports which gas is selectively introduced or removed from said at least two gas channels; and at least a first blood manifold means mounted in said housing and adjacent to said at least a first core for delivering blood to said blood receiving channels.
Claim 3
Dependent Claim
20 words
The device of claim 1 wherein each of said individual gas permeable membranes comprises a plurality of hollow fiber membranes.
Claim 4
Dependent Claim
39 words
The device of claim 1 wherein each of said individual gas permeable membranes comprises a plurality of hollow fiber membranes, said hollow fiber membrane filling from about 40 to about 60 percent of each of said blood receiving channels.
Claim 5
Dependent Claim
38 words
The device of claim 3 wherein said at least a first thermally conductive core comprises a cylindrically shaped bellows formed with bellows pleats, with said blood receiving channels being defined between adjacently positioned ones of said bellows pleats.
Claim 6
Dependent Claim
26 words
The device of claim 1 wherein each of said individual gas permeable membranes comprises a plurality of hollow fiber membranes woven together by an inert fiber.
Claim 7
Dependent Claim
34 words
The device of claim 5 wherein said at least a first thermally conductive core comprises a cylindrically shaped bellows, with said blood receiving channels being defined between adjacently positioned ones of said bellow pleats.
Claim 8
Dependent Claim
106 words
The device of claim 1 wherein said at least a first blood manifold means is an elongated body mounted adjacent to the side of said at least a first core, said manifold means body being formed with at least a first main conduit, and a plurality of protrusions radiating out from said body which include one or more conduits communicating with said at least a first main conduit, each of said protrusions being positioned in a respective one of said channels, whereby blood is introduced into said at least a first main conduit and enters said blood receiving channels through id one or more protrusion conduits.
Claim 9
Dependent Claim
21 words
The device of claim 7 wherein each of said individual gas permeable membranes comprises of a plurality of hollow fiber membranes.
Claim 10
Dependent Claim
39 words
The device of claim 7 wherein each of said individual gas permeable membranes comprises a plurality of hollow fiber membranes, said hollow fiber membranes filling from about 40 to about 60 percent of each of said blood receiving channels.
Claim 11
Dependent Claim
69 words
The device of claim 9 wherein said at leas a first thermally conductive core comprises a cylindrically shaped bellows formed with bellows pleats arranged about the circumference of said core, with said blood receiving channels being defined between adjacently positioned ones of said bellows pleats, and wherein said individual gas permeable membranes pass about said core to position said opposite open ends along the same side of said core.
Claim 12
Dependent Claim
27 words
The device of claim 10 wherein said outwardly radiating protrusions of said at least a first blood manifold are positioned between said adjacently positioned membrane open ends.
Claim 13
Dependent Claim
55 words
The device of claim 11 wherein said at least a first gas manifold is mounted at a side of said at least a first blood manifold to place each of said at least two gas channels in communication with said respective membrane open ends on either side of said at least a first blood manifold.
Claim 14
Dependent Claim
19 words
The device of claim 12 wherein said membrane open ends are fixed in position by a polymeric potting material.
Claim 15
Dependent Claim
39 words
The device of claim 13 further including a second blood manifold for receiving blood from said blood receiving channels, said second blood manifold being formed with a blood exit through which blood having entered said second blood manifold exits.
Claim 16
Dependent Claim
48 words
The device of claim 9 wherein said at least a first thermally conductive core is a cylindrical bellows formed with bellows pleats arranged longitudinally along said at least a first thermally conductive core, with said blood receiving channels being defined between adjacently positioned ones of said bellows pleats.
Claim 17
Dependent Claim
39 words
The device of claim 15 further including a second blood manifold for receiving blood from said blood receiving channels, said second blood manifold being formed with a blood exit through which blood having entered said second blood manifold exits.
Claim 18
Dependent Claim
27 words
The device of claim 7 wherein each of said individual gas permeable membranes comprises of a plurality of hollow fiber membranes woven together by an inert fiber.
Claim 19
Dependent Claim
74 words
The device of claim 17 wherein said at least a first thermally conductive core comprises a cylindrically shaped bellows formed with bellows pleats arranged about the circumference of said core, with said blood receiving channels being defined between adjacently positioned ones of said bellows pleats, and wherein said individual gas permeable membranes pass about said core to position said opposite membrane open ends adjacent to one another along the same side of said core.
Claim 20
Dependent Claim
27 words
The device of claim 18 wherein said outwardly radiating protrusion of said at least a first blood manifold are positioned between said adjacently positioned membrane open ends.
Claim 21
Dependent Claim
48 words
The device of claim 17 wherein said at least a first thermally conductive core is a cylindrical bellows formed with bellows pleats arranged longitudinally along said at least a first thermally conductive core, with said blood receiving channels being defined between adjacently positioned ones of said bellows pleats.
Claim 22
Dependent Claim
39 words
The device of claim 20 further including a second blood manifold for receiving blood from said blood receiving channels, said second blood manifold being formed with a blood exit through which blood having entered said second blood manifold exits.
Claim 23
Dependent Claim
110 words
The device of claim 1 wherein a first of said at least two gas channels communicates a first end of each of said gas permeable membranes, with the second of said at least two gas channels communicating with the opposite end of each of said gas permeable membranes, said first and second gas channels being arranged side by side and separated by a partitioning wall to isolate said at least two gas channels from one another, whereby gas entering one of said at least two gas channels passes through said gas permeable membrane end associated therewith, through said membranes and into said other of said at least two gas channels.
Claim 24
Dependent Claim
40 words
The device of claim 1 wherein said individual gas permeable membranes ar arranged in each of said blood receiving channels to provide that blood will pass across said gas permeable membranes in a direction substantially perpendicular to said gas pathways.
Claim 25
Dependent Claim
36 words
The device of claim 1 wherein each of said individual gas permeable membranes comprises a plurality of hollow fiber membranes, said hollow fiber membranes filling at least 40 percent of each of said blood receiving channels.
Claim 26
Dependent Claim
36 words
The device of claim 1 wherein each of said individual gas permeable membranes comprises a plurality of hollow fiber membranes, said hollow fiber membranes filling more than 60 percent of each of said blood receiving channels.
Claim 27
Dependent Claim
27 words
The device of claim 1 wherein said plurality of parallel blood receiving channels are oriented about an external circumference of said at least a first external surface.
Claim 28
Dependent Claim
24 words
The device of claim 1 wherein said plurality of parallel blood receiving channels are defined longitudinally along said at least a first external surface.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-06-09 | 1995-12-09 | 1996-06-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-06-09 | 1999-12-09 | 2000-06-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-06-09 | 2003-12-09 | 2004-06-09 | $7700.00 | Window Closed / Lapsed |