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US4376095A Expired / Lapsed US ⏱️ 0.0 years remaining

Hollow fiber-type artificial lung having enclosed heat exchanger

Assignee: Terumo Corp
•
Filing: 1981-08-14
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Granted: 1983-03-08
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Expires: 2001-08-14
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Abstract

Abstract A hollow fiber-type artificial lung having an enclosed heat exchanger comprises a first housing and a second housing connected together coaxially. A gas exchange chamber is defined in the first housing by a pair of spaced walls and a bundle of hollow fibers designed for gas exchange arranged in the first housing and between the pair of walls. The hollow fiber bundle is preferably constricted at the central portion to increase the packing ratio of the hollow fibers. The second housing is connected to the first housing by way of a blood chamber and has a pair of spaced apart walls, and multiple tubes which extend lengthwise between the pair of walls to effect heat exchange between a circulating heat exchange medium and the blood flowing through the multiple tubes.

Inventors

  • 👤 Hiroshi Hasegawa

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 21:52
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1698; A61M1/1621; A61M1/1623; A61M1/1627; A61M1/1629; A61M1/36; A61M1/3621; A61M1/3623; B; B01; B01D; B01D63/00; B01D63/02; B01D63/021; B01D63/022; B01D63/033; Y; Y10; Y10S; Y10S128/00; Y10S128/03; Y10S261/00; Y10S261/28

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 430 words
A hollow fiber-type artificial lung having an enclosed heat exchanger comprising: (a) an oxygenator section, said oxygenator section including: a first housing; a bundle of a multiplicity of hollow fibers for gas exchange, said hollow fibers having mean pore sizes of 200 to 2,000 angstroms and being gas permeable and liquid impermeable, said hollow fibers being physically separated from one another and arranged side by side within and along the longitudinal direction of said first housing; first and second walls liquid-tightly carrying said hollow fibers at the end portions of said hollow fibers with said end portions of said hollow fibers left open, said first and second walls defining an oxygen chamber with the inner wall of said first housing and outer wall surfaces of said hollow fibers; oxygen inlet and outlet means communicating with said oxygen chamber; and a first blood circulation opening communicating with an interstitial space of said hollow fibers externally of said first wall; (b) a multiple tube-type heat exchanger section, said heat exchanger section including: a second housing; a multiplicity of tubes physically separated from one another and arranged side by side within and along the longitudinal direction of said second housing; third and fourth walls liquid-tightly carrying said tubes at the end portions of said tubes, with said end portions of said tubes left open, said third and fourth walls defining at heat exchange medium chamber with the inner wall of said second housing and the outer wall surfaces of said tubes; heat exchange medium inlet and outlet means communicating with said heat exchange medium chamber; and a second blood circulation opening communicating with an interstitial space of said tubes externally of said fourth wall; and (c) a blood chamber defining means defining a blood chamber and coupling said oxygenator section directly to said heat exchanger section in substantially coaxial relation and with said open ends of said hollow fibers in face-to-face relation with said open ends of said heat exchanger tubes, said blood chamber being interposed between said second wall of said oxygenator section and said third wall of said heat exchanger section and said second and third walls defining end walls of said blood chamber, said blood chamber communicating said oxygenator and heat exchanger by facing end openings in said hollow fibers carried by said second wall and end openings in said tubes carried by said third wall, and said blood chamber serving as a blood flow buffer chamber so that the processing capability of said oxygenator section and that of said heat exchanger section may be determined independently of each other.
Claim 2
Dependent Claim 430 words
A hollow fiber-type artificial lung having an enclosed heat exchanger comprising: (a) an oxygenator section, said oxygenator section including: a first housing; a bundle of a multiplicity of hollow fibers for gas exchange, said hollow fibers having mean pore sizes of 200 to 2,000 angstroms and being gas permeable and liquid impermeable, said hollow fibers being physically separated from one another and arranged side by side within and along the longitudinal direction of said first housing; first and second walls liquid-tightly carrying said hollow fibers at the end portions of said hollow fibers with said end portions of said hollow fibers left open, said first and second walls defining an oxygen chamber with the inner wall of said first housing and outer wall surfaces of said hollow fibers; oxygen inlet and outlet means communicating with said oxygen chamber; and a first blood circulation opening communicating with an interstitial space of said hollow fibers externally of said first wall; (b) a multiple tube-type heat exchanger section, said heat exchanger section including: a second housing; a multiplicity of tubes physically separated from one another and arranged side by side within and along the longitudinal direction of said second housing; third and fourth walls liquid-tightly carrying said tubes at the end portions of said tubes, with said end portions of said tubes left open, said third and fourth walls defining at heat exchange medium chamber with the inner wall of said second housing and the outer wall surfaces of said tubes; heat exchange medium inlet and outlet means communicating with said heat exchange medium chamber; and a second blood circulation opening communicating with an interstitial space of said tubes externally of said fourth wall; and (c) a blood chamber defining means defining a blood chamber and coupling said oxygenator section directly to said heat exchanger section in substantially coaxial relation and with said open ends of said hollow fibers in face-to-face relation with said open ends of said heat exchanger tubes, said blood chamber being interposed between said second wall of said oxygenator section and said third wall of said heat exchanger section and said second and third walls defining end walls of said blood chamber, said blood chamber communicating said oxygenator and heat exchanger by facing end openings in said hollow fibers carried by said second wall and end openings in said tubes carried by said third wall, and said blood chamber serving as a blood flow buffer chamber so that the processing capability of said oxygenator section and that of said heat exchanger section may be determined independently of each other.
Claim 3
Dependent Claim 77 words
The hollow fiber-type artificial lung having an enclosed heat exchanger as claimed in claim 1, in which said first and second housings each have connection terminuses of the same diameter, said connection terminuses having external threads advancing in mutually opposite directions, and said blood chamber defining means includes a threaded connector ring, said first and second housings being connected by said threaded connector ring externally of said connection terminuses with a sealing member interposed between said terminuses.
Claim 4
Dependent Claim 75 words
The hollow fiber-type artificial lung having an enclosed heat exchanger as claimed in claim 1, in which said first and second housings have connection terminuses of different diameters, said connection terminuses having external threads advancing in mutually opposite directions, and said blood chamber defining means includes a threaded connector ring, said first and second housings being connected by said threaded connector ring externally of said connection terminuses with a sealing member interposed between said terminuses.
Claim 5
Dependent Claim 50 words
The hollow fiber-type artificial lung having an enclosed heat exchanger as claimed in any one of claims 1, 2 or 3, in which the inner wall of said first housing comprises a constrictor for constricting the hollow fiber bundle at a substantially mid portion longitudinally of said hollow fiber bundle.
Claim 6
Dependent Claim 40 words
The hollow fiber-type artificial lung having an enclosed heat exchanger as claimed in any one of claims 1, 2 or 3, wherein said hollow fibers of said oxygenator section are provided in a number of from between 10,000 and 60,000.
Claim 7
Dependent Claim 54 words
The housing fiber-type artificial lung having an enclosed heat exchanger as claimed in any one of claims 1, 2 or 3, in which said hollow fibers have an inside diameter of about 100 to 1000 μm, a wall thickness of about 10 to 50 μm and a porosity of about 20 to 80 percent.
Claim 8
Dependent Claim 30 words
The hollow fiber-type artificial lung having an enclosed heat exchanger as claimed in any one of claims 1, 2 or 3, in which said hollow fibers are made of polyolefins.
Claim 9
Dependent Claim 48 words
The housing fiber-type artificial lung having an enclosed heat exchanger as claimed in claim 7, in which said hollow fibers have an inside diameter of about 100 and 1000 μm, a wall thickness of about 10 to 50 μm and a porosity of about 20 to 80 percent.
Claim 10
Dependent Claim 34 words
The hollow fiber-type artificial lung having an enclosed heat exchanger as claimed in claim 8, wherein said hollow fibers of said oxygenator section are provided in a number of from between 10,000 and 60,000.

References Cited (Backward Citations)

US3856475A Cited
US3807958A Cited
US3998593A Cited
DE2617208A1 Cited
US4138288A Cited
US4239729A Cited
US4268279A Cited
US4306018A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-03-07 1986-09-06 1987-03-08 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-03-07 1990-09-06 1991-03-08 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-03-07 1994-09-06 1995-03-08 $7700.00 Window Closed / Lapsed

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