US5334189A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for controlled diffusion of a chemical substance
Assignee: Individual
•
Filing: 1991-06-03
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Granted: 1994-08-02
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Expires: 2011-06-03
Abstract
Abstract A device and methods of use and manufacture are disclosed for controlled diffusion of chemical substances of interest intraorally. The device includes ported structure formed of material that is substantially impermeable to the substance of interest, an inner wall of which defines a compartment communicating through the ports with the exterior of the device. A dispersed layer is formed in the compartment of material having limited permeability, the layer being formed so that contact is maintained with the inner wall across the ports after formation, the ports and the layer thus providing a region of permeability to diffusion of the chemical substance of interest. In use, either the chemical substance of interest or a composition capable of binding itself to the chemical substance of interest is placed in the compartment and the device is positioned in the mouth of a subject where it may remain for extended periods.
Inventors
- 👤 Stephen E. Wade
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:38
CPC Classifications
A; A61; A61M; A61M31/00; A61M31/002
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
125 words
A device for controlled diffusion of a chemical substance of interest between a body fluid and said device, said device comprising: a structure impermeable to the substance of interest, an inwardly facing surface of which surrounds and in part defines a compartment, said structure having a port defined therein; and a diffusion layer formed in said structure characterized by selective permeability to the substance of interest while being substantially impermeable to other substances and the substance of interest bound to any of said other substances, said layer comprising at the time of formation in said compartment a dispersed solution coating substantially all of said inwardly facing surface of said structure thereby establishing said layer in adherence with said inwardly facing surface and across said port.
Claim 2
Independent Claim
125 words
A device for controlled diffusion of a chemical substance of interest between a body fluid and said device, said device comprising: a structure impermeable to the substance of interest, an inwardly facing surface of which surrounds and in part defines a compartment, said structure having a port defined therein; and a diffusion layer formed in said structure characterized by selective permeability to the substance of interest while being substantially impermeable to other substances and the substance of interest bound to any of said other substances, said layer comprising at the time of formation in said compartment a dispersed solution coating substantially all of said inwardly facing surface of said structure thereby establishing said layer in adherence with said inwardly facing surface and across said port.
Claim 3
Dependent Claim
18 words
The device of claim 1 wherein said structure includes removable closure means for allowing access to said compartment.
Claim 4
Dependent Claim
18 words
The device of claim 1 wherein said device is about 25 mm long and 3 mm in diameter.
Claim 5
Dependent Claim
28 words
The device of claim 1 further comprising one of a composition capable of binding to itself the substance of interest and said substance of interest in said compartment.
Claim 6
Dependent Claim
45 words
The device of claim 1 wherein said structure includes a main body having said inwardly facing surface and said port thereat, and at least a first flow connector connected with said main body to allow flow of matter to said compartment from a remote location.
Claim 7
Dependent Claim
26 words
The device of claim 5 wherein said structure includes a second flow connector connected with said main body to allow flow of matter from said compartment.
Claim 8
Dependent Claim
23 words
The device of claim 1 wherein said structure includes a plurality of ports, said layer extending across all of said ports after formation.
Claim 9
Dependent Claim
68 words
The device of claim 7 wherein said body fluid is saliva in a subject's mouth and wherein said structure is configured for placement in the subject's mouth and has an outer surface, each of said ports having first and second spaced apertures, said first apertures located at said inwardly facing surface and said second apertures being located at said outer surface and being larger than said first apertures.
Claim 10
Dependent Claim
49 words
The device of claim 8 further comprising supple securing means connected with said structure for securing said structure entirely in the subject's mouth, said supple securing means having sufficient length to secure said structure to a subject's tooth while leaving a length thereof between said structure and the tooth.
Claim 11
Dependent Claim
45 words
The device of claim 8 wherein the substance of interest is present in bound and free fractions in the saliva, and wherein said diffusion layer is characterized by permeability to diffusion of the free fraction and not the bound fraction of the substance of interest
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-08-01 | 1998-01-31 | 1998-08-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-08-01 | 2002-01-31 | 2002-08-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-08-01 | 2006-01-31 | 2006-08-02 | $7700.00 | Window Closed / Lapsed |