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US5328846A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for removing exogenous deposits from hydrophilic contact lenses

Assignee: Penn State Research Foundation
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Filing: 1993-10-18
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Granted: 1994-07-12
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Expires: 2013-10-18
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Abstract

Abstract The present invention describes a method and composition for removing exogenous mucin and protein-mucin deposits from hydrophilic contact lenses.

Inventors

  • 👤 Frederick C. Wedler

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 19:20
CPC Classifications
C; C11; C11D; C11D3/00; C11D3/16; C11D3/38; C11D3/386; C11D3/0005; C11D3/0078; Y; Y10; Y10S; Y10S134/00; Y10S134/901

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 101 words
A method for removing mucin and mucin-containing deposits from a contact lens, which method comprises: providing a contact lens cleaning solution comprising a buffering agent, a mucin degrading enzyme and calcium ions in an amount sufficient to maintain said enzyme's stability, said mucin-degrading enzyme consisting of alpha-amylase from Bacillus licheniformis, in an effective amount sufficient to remove a mucin or mucin-containing deposit from a contact lens; placing a contact lens having a mucin or mucin-containing deposit in contact with said cleaning solution at or near room temperature; and allowing a sufficient period of time to elapse to allow for said removal.
Claim 2
Independent Claim 101 words
A method for removing mucin and mucin-containing deposits from a contact lens, which method comprises: providing a contact lens cleaning solution comprising a buffering agent, a mucin degrading enzyme and calcium ions in an amount sufficient to maintain said enzyme's stability, said mucin-degrading enzyme consisting of alpha-amylase from Bacillus licheniformis, in an effective amount sufficient to remove a mucin or mucin-containing deposit from a contact lens; placing a contact lens having a mucin or mucin-containing deposit in contact with said cleaning solution at or near room temperature; and allowing a sufficient period of time to elapse to allow for said removal.
Claim 3
Dependent Claim 21 words
The method of claim 1 wherein the solution contains a protease suitable for removing a proteinaceous deposit from a contact lens.
Claim 4
Dependent Claim 37 words
The method of claim 1 with the added step of: finger rubbing said contact lens to remove mucin and mucin containing deposits, said finger rubbing occurring when said contact lens is in contact with said cleaning solution.
Claim 5
Independent Claim 111 words
A method for removing mucin and mucin-containing deposits from a contact lens, which method comprises: providing a contact lens cleaning solution comprising a mucin-degrading enzyme composition consisting essentially of alpha-amylase from, Bacillus licheniformis, said alpha-amylase from Bacillus licheniformis present in an effective amount sufficient to remove a mucin or mucin-containing deposit from a contact lens, said contact lens cleaning solution further including a buffering agent and calcium ions in an amount sufficient to maintain enzyme stability; placing a contact lens having a mucin or mucin-containing deposit in contact with said cleaning solution at or near room temperature; and allowing a sufficient period of time to elapse to allow for said removal.
Claim 6
Independent Claim 111 words
A method for removing mucin and mucin-containing deposits from a contact lens, which method comprises: providing a contact lens cleaning solution comprising a mucin-degrading enzyme composition consisting essentially of alpha-amylase from, Bacillus licheniformis, said alpha-amylase from Bacillus licheniformis present in an effective amount sufficient to remove a mucin or mucin-containing deposit from a contact lens, said contact lens cleaning solution further including a buffering agent and calcium ions in an amount sufficient to maintain enzyme stability; placing a contact lens having a mucin or mucin-containing deposit in contact with said cleaning solution at or near room temperature; and allowing a sufficient period of time to elapse to allow for said removal.
Claim 7
Dependent Claim 21 words
The method of claim 4 wherein the solution contains a protease suitable for removing a proteinaceous deposit from a contact lens.
Claim 8
Dependent Claim 37 words
The method of claim 4 with the added step of: finger rubbing said contact lens to remove mucin and mucin containing deposits, said finger rubbing occurring when said contact lens is in contact with said cleaning solution.

References Cited (Backward Citations)

EP0093784A1 Cited
EP0140669A1 Cited
US4614549A Cited
US4710313A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-07-11 1998-01-10 1998-07-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-07-11 2002-01-10 2002-07-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-07-11 2006-01-10 2006-07-12 $7700.00 Window Closed / Lapsed

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