Patent US5324481A successfully refreshed from Google Patents.
US5324481A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Carousel for assay specimen carrier
Assignee: Abbott Laboratories
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Filing: 1991-06-03
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Granted: 1994-06-28
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Expires: 2011-06-03
Abstract
Abstract An assay carrier for carrying and positioning a plurality of reaction cells each carrying a single assay, and for carrying and positioning a plurality of reagent packs, for use in selectively performing any one of a plurality of immunoassays on each of the plurality of cells in the carrier.
Inventors
- 👤 Chadwick M. Dunn
- 👤 Cass J. Grandone
- 👤 Stephen L. Herchenbach
- 👤 Robert J. Nelson
- 👤 James T. Tyranski
- 👤 Gary L. Zuck
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-10 01:05
CPC Classifications
B; B01; B01L; B01L9/00; B01L9/06; G; G01; G01N; G01N35/00; G01N35/02; G01N35/025; G01N35/10; G01N35/1002; B01L3/00; B01L3/50; B01L3/508; B01L3/5082; B01L3/50825; G01N2035/00346; G01N2035/00356; G01N2035/00386; G01N35/00584; G01N35/00722; G01N35/00732; G01N2035/00742; G01N2035/00752; G01N35/04; G01N2035/0401; G01N2035/0429; G01N2035/0436; G01N2035/0439; G01N2035/0446; G01N2035/0451; G01N35/1081; G01N35/1083; G01N2035/1086; Y; Y10; Y10T; Y10T436/00; Y10T436/11; Y10T436/113332
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
288 words
An apparatus for use in a biological sample analyzer, said apparatus comprising: a. an outer, compartmentalized ring having inner and outer perimeters for defining a carousel with a plurality of compartments, each compartment adapted for receiving a cartridge for holding a test sample, wherein said ring includes an upstanding inner side wall about said inner perimeter, said ring inner side wall having a top edge and a bottom edge; b. a centralized hub disposed inwardly of the outer ring c. a plurality of ribs radiating outwardly from said hub and supporting said ring above and concentric with said hub, d. a carousel carrier disposed above said hub and concentric with the inner perimeter of the ring, wherein said carrier comprises a well adapted for receiving a plurality of reagent packs, said well having an upstanding circular outer side wall having a top edge and a bottom edge, said outer side wall spaced radially outward from the hub and common with and forming a boundary with the carrier, said carrier further comprises: (i) a flange extending about a periphery of the top edge of said outer side wall and radiating outwardly therefrom; and (ii) resilient mounting tabs located on said side wall and movable between an extended position and a retracted position, wherein said carrier may be installed in said ring by withdrawing the tabs to the retracted position and inserting said carrier axially in said ring with said flange engaging a top edge of said ring inner side wall and, when said tabs are moved to the extended position, the tabs engaging a bottom edge of said ring inner side wall; and e. a drive plate for communicating with a motive means for driving and indexing the apparatus.
Claim 2
Independent Claim
288 words
An apparatus for use in a biological sample analyzer, said apparatus comprising: a. an outer, compartmentalized ring having inner and outer perimeters for defining a carousel with a plurality of compartments, each compartment adapted for receiving a cartridge for holding a test sample, wherein said ring includes an upstanding inner side wall about said inner perimeter, said ring inner side wall having a top edge and a bottom edge; b. a centralized hub disposed inwardly of the outer ring c. a plurality of ribs radiating outwardly from said hub and supporting said ring above and concentric with said hub, d. a carousel carrier disposed above said hub and concentric with the inner perimeter of the ring, wherein said carrier comprises a well adapted for receiving a plurality of reagent packs, said well having an upstanding circular outer side wall having a top edge and a bottom edge, said outer side wall spaced radially outward from the hub and common with and forming a boundary with the carrier, said carrier further comprises: (i) a flange extending about a periphery of the top edge of said outer side wall and radiating outwardly therefrom; and (ii) resilient mounting tabs located on said side wall and movable between an extended position and a retracted position, wherein said carrier may be installed in said ring by withdrawing the tabs to the retracted position and inserting said carrier axially in said ring with said flange engaging a top edge of said ring inner side wall and, when said tabs are moved to the extended position, the tabs engaging a bottom edge of said ring inner side wall; and e. a drive plate for communicating with a motive means for driving and indexing the apparatus.
Claim 3
Dependent Claim
43 words
The apparatus of claim 1, wherein said apparatus is a circular carousel having a center hub and an outer perimeter and wherein said compartments are angularly spaced about the outer perimeter and said carrier is mounted in axial alignment with the center hub.
Claim 4
Dependent Claim
32 words
The apparatus of claim 1, wherein said carousel carrier includes a lock mechanism movable between a cartridge engaging position and a cartridge non-engaging position for selectively locking said cartridges in said compartments.
Claim 5
Dependent Claim
42 words
The apparatus of claim 1, further including means for directing an air flow of predetermined temperature into communication with the cartridges and reagent packs for maintaining the sample within said cartridges and reagents in said reagent packs within a predetermined temperature range.
Claim 6
Dependent Claim
36 words
The apparatus of claim 1, further comprising reagent pack means for containing and isolating containers of test reagents associated with a predetermined immunoassay, wherein said reagent pack means is releasably retained within said carousel carrier well.
Claim 7
Dependent Claim
16 words
The apparatus of claim 1, further including means for biasing the tabs into the extended position.
Claim 8
Dependent Claim
72 words
The apparatus of claim 6, wherein said carrier is constructed of a semi-rigid, resilient material with integral, vertically extending leaf springs formed in said outer side wall, each spring having an elongate leg with opposite ends, one of said ends secured to said side wall and the other of said ends free of said side wall, wherein each of said tabs is secured to the free end of one of said springs.
Claim 9
Dependent Claim
36 words
The apparatus of claim 1, wherein each of said tabs includes an inclined edge to facilitate withdrawal of the tabs from the extended position to the retracted position as the carrier is inserted in the ring.
Claim 10
Dependent Claim
223 words
The apparatus of claim 1, wherein said ring includes an upstanding inner side wall about said inner perimeter, said ring inner side wall having a top edge including an annular recess extending thereabout for forming a recessed seat, and wherein each of said cartridges includes a radially extended support surface of predetermined size adapted to be received by and seated in the recessed seat on the inner ring side wall, said carrier further comprising: a. a flange extending about the periphery of the top edge of the carrier side wall and radiating outwardly therefrom, said flange adapted to be seated on the top edge of said inner ring side wall and said flange having an outer edge extending over said recessed seat and said cartridge support surface for locking said cartridges in said ring; b. notches in the outer edge of said flange and having opposite sides and an end wall for defining an enclosed area larger than the predetermined size of said cartridge support surface; c. means for selectively axially rotating said carrier between a first position, wherein when said notches are aligned with said cartridge support surfaces, said cartridges may be removed from or placed in said ring and a second position wherein when said notches are offset from said cartridge surfaces, whereby said flange retains the cartridges in said ring.
Claim 11
Dependent Claim
28 words
The apparatus of claim 9, further including locking means associated with said rotating means for selectively retaining the carrier in either the first position or the second position.
Claim 12
Dependent Claim
137 words
The apparatus of claim 1, said carrier further including an upstanding spindle concentric with and disposed inwardly of said carrier outer side wall, said spindle including an upper end having an enlarged locator surface extending radially outward from the spindle, and wherein there is further included a container means for containing test fluids associated with a predetermined analysis, the carrier adapted for receiving and carrying in said well a plurality of said container means, each of said container means comprising: a. an upstanding support having a top and bottom; b. a visual locator means at the top of said support and adapted to be aligned with the locator surface on said spindle, whereby said support is positioned in the well; and c. at least one fluid chamber mounted in said container means intermediate its top and bottom.
Claim 13
Dependent Claim
28 words
The apparatus of claim 11, wherein each of said container means includes a plurality of fluid chambers for isolating a plurality of fluids associated with a predetermined analysis.
Claim 14
Dependent Claim
31 words
The apparatus of claim 4, wherein said means for directing the air flow further comprises an annular deflector attached to and circumscribing said hub for directing air away from said hub.
Claim 15
Dependent Claim
81 words
The apparatus of claim 13, wherein said drive plate further comprises: a. a cylindrical outer wall having a top edge and a bottom edge; b. an annular flange around the top edge extending radially outward therefrom; c. means for securing the flange to the ring; and d. a bottom surface extending radially inwardly from the bottom edge, said bottom surface including a circular track adapted for engaging motive means and a central opening defining a passageway for said flow of air.
Claim 16
Dependent Claim
29 words
The apparatus of claim 14, wherein said ring further includes a deflector for directing the air flowing through said drive plate central opening toward the perimeter of the ring.
Claim 17
Independent Claim
302 words
An apparatus for use in a biological sample analyzer and for holding a plurality of cartridges for holding samples to be analyzed, said apparatus comprising: a. a carousel having an outer compartmentalized ring having inner and outer perimeters and a plurality of annular spaced compartments in said ring, each compartment adapted for receiving one of a plurality of cartridges, a central hub disposed inwardly of the ring, and a plurality of ribs radiating outwardly from the hub and supporting said ring above and concentric with the hub; b. a carousel carrier comprising a well having an upstanding circular outer side wall with a top edge and a bottom edge, said carrier well positioned above said hub with the outer side wall inside and concentric with the inner perimeter of the ring, the carrier further including an upstanding spindle concentric with and disposed inwardly of said carrier outer side wall, said spindle including an upper end having an enlarged locator surface extending radially outwardly from the spindle; c. a reagent pack means for holding a plurality of test reagents, said carrier adapted for receiving and carrying in said well a plurality of said reagent pack means, each of said reagent pack means including an upstanding support having a top and bottom, a locator means at the top of said support for aligning the reagent pack means with the locator surface on said spindle, whereby the support is positioned in the well; d. a drive plate mounted on said carousel for communicating with a motive means for indexing said carousel and said carrier; and e. means associated with said carousel and said carrier for directing an air flow of predetermined temperature into communication with the cartridges and the reagent pack means for maintaining the samples and test reagents therein within a predetermined temperature range.
Claim 18
Independent Claim
302 words
An apparatus for use in a biological sample analyzer and for holding a plurality of cartridges for holding samples to be analyzed, said apparatus comprising: a. a carousel having an outer compartmentalized ring having inner and outer perimeters and a plurality of annular spaced compartments in said ring, each compartment adapted for receiving one of a plurality of cartridges, a central hub disposed inwardly of the ring, and a plurality of ribs radiating outwardly from the hub and supporting said ring above and concentric with the hub; b. a carousel carrier comprising a well having an upstanding circular outer side wall with a top edge and a bottom edge, said carrier well positioned above said hub with the outer side wall inside and concentric with the inner perimeter of the ring, the carrier further including an upstanding spindle concentric with and disposed inwardly of said carrier outer side wall, said spindle including an upper end having an enlarged locator surface extending radially outwardly from the spindle; c. a reagent pack means for holding a plurality of test reagents, said carrier adapted for receiving and carrying in said well a plurality of said reagent pack means, each of said reagent pack means including an upstanding support having a top and bottom, a locator means at the top of said support for aligning the reagent pack means with the locator surface on said spindle, whereby the support is positioned in the well; d. a drive plate mounted on said carousel for communicating with a motive means for indexing said carousel and said carrier; and e. means associated with said carousel and said carrier for directing an air flow of predetermined temperature into communication with the cartridges and the reagent pack means for maintaining the samples and test reagents therein within a predetermined temperature range.
Claim 19
Dependent Claim
149 words
The apparatus of claim 16, wherein said carousel ring includes an upstanding inner side wall about said inner perimeter, said inner side wall having a top edge and a bottom edge, and wherein said carrier further includes: a. a flange extending about the periphery of the top edge of the carrier outer side wall and radiating outwardly therefrom; b. resilient mounting tabs located on the outer side wall and movable between an extended position and a retracted position, wherein said carrier may be installed in said ring by withdrawing the tabs to the retracted position and inserting said carrier axially in said ring with said flange engaging the top edge of said ring inner side wall, and when said tabs are moved to the extended position, the tabs engaging the bottom edge of said ring inner side wall; and c. means for biasing the tabs into the extended position.
Claim 20
Dependent Claim
232 words
The apparatus of claim 16, wherein said ring includes an upstanding inner side wall about said inner perimeter, said ring inner side wall having a top edge including an annular recess for forming a recessed seat, and wherein each of said cartridges includes a radially extending support surface of predetermined size adapted to be received by and seated in the recessed seat, said carrier further comprising: a. a flange extending about the periphery of the top edge of the carrier side wall and radiating outwardly therefrom, said flange adapted to be seated on the top edge of said ring inner side wall, the flange having an outer edge extending over said recessed seat and said cartridge surface for locking said cartridges in said ring; b. notches in the outer edge of said ring, having opposite sides and an end wall for defining an enclosed area larger than the cartridge support surface; c. means for selectively axially rotating said carrier between a first position, wherein when said notches are aligned with said cartridge support surfaces, said cartridges may be removed from or placed in said ring and a second position wherein when said notches are offset from said cartridge support surfaces, whereby said flange retains the cartridges in said ring; d. locking means associated with said rotating means for selectively retaining the carrier flange in either the first position or the second position.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-06-27 | 1997-12-27 | 1998-06-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-06-27 | 2001-12-27 | 2002-06-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-06-27 | 2005-12-27 | 2006-06-28 | $7700.00 | Window Closed / Lapsed |