Patent US5322689A successfully refreshed from Google Patents.
US5322689A
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Topical aromatic releasing compositions
Assignee: Richardson Vicks Inc
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Filing: 1992-03-10
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Granted: 1994-06-21
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Expires: 2012-03-10
Abstract
Abstract The present invention relates to topical aromatic releasing compositions substantially free from petrolatum and containing one or more volatile aromatic compounds selected from the group consisting of menthol, camphor and eucalyptus oil and mixtures thereof. In further embodiments, these compositions contain one or more topical actives, and are also useful for providing relief from symptoms associated with respiratory disorders.
Inventors
- 👤 Timothy J. Hughes
- 👤 George E. Deckner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 11:33
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/72; A61K8/81; A61K8/8141; A61K8/8147; A61K45/00; A61K45/06; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K47/12; A61K47/30; A61K47/32; A61K9/00; A61K9/0012; A61K9/0014; A61K9/007; A61K9/10; A61K9/107; A61P; A61P11/00; A61P29/00; A61P31/00; A61P31/04; A61Q; A61Q13/00
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
161 words
A topical composition useful for releasing an aromatic decongestant composition substantially free from petrolatum comprising: (a) from about 0.025% to about 3% of a carboxylic copolymer comprising polymers of a monomeric mixture selected from the group consisting of acrylic, methacrylic and ethacrylic acids, about 1 to about 3.5 weight percent of an acrylate ester of the formula: ##STR5## wherein R is hydrogen or an alkyl radical containing 10 to 30 carbon atoms and R 1 is hydrogen, methyl or ethyl, and 0.1 to 0.6 weight percent of a polymerizable cross-linking polyalkenyl polyether of a polyhydric alcohol containing more than one alkenyl ether group per molecule wherein the parent polyhydric alcohol contains at least 3 carbon atoms and at least 3 hydroxyl groups, (b) from about 0.1% to about 30% of one or more volatile aromatic compounds selected from the group consisting of menthol, camphor and eucalyptus oil and mixtures thereof wherein said composition is in the form of an oil-in-water emulsion.
Claim 2
Dependent Claim
161 words
A topical composition useful for releasing an aromatic decongestant composition substantially free from petrolatum comprising: (a) from about 0.025% to about 3% of a carboxylic copolymer comprising polymers of a monomeric mixture selected from the group consisting of acrylic, methacrylic and ethacrylic acids, about 1 to about 3.5 weight percent of an acrylate ester of the formula: ##STR5## wherein R is hydrogen or an alkyl radical containing 10 to 30 carbon atoms and R 1 is hydrogen, methyl or ethyl, and 0.1 to 0.6 weight percent of a polymerizable cross-linking polyalkenyl polyether of a polyhydric alcohol containing more than one alkenyl ether group per molecule wherein the parent polyhydric alcohol contains at least 3 carbon atoms and at least 3 hydroxyl groups, (b) from about 0.1% to about 30% of one or more volatile aromatic compounds selected from the group consisting of menthol, camphor and eucalyptus oil and mixtures thereof wherein said composition is in the form of an oil-in-water emulsion.
Claim 3
Dependent Claim
51 words
A topical aromatic releasing composition according to claim 1 the polymer component contains from about 96 to about 97.9 weight percent of acrylic acid and from about 2.5 to about 3.5 weight percent of acrylic esters wherein the alkyl group contains 12 to 22 carbon atoms, and R 1 is methyl.
Claim 4
Dependent Claim
49 words
A topical aromatic releasing composition according to claim 2 wherein the acrylate ester of the carboxylic copolymer is stearyl methacrylate, and wherein the copolymer comprises from about 0.2 to 0.4 weight percent of the crosslinking monomer selected from the group consisting of allyl pentaerythritol, trimethylolpropane diallylether or allyl sucrose.
Claim 5
Dependent Claim
21 words
A topical aromatic releasing composition according to claim 3 which further comprises from about 0.1% to about 20% of a humectant.
Claim 6
Dependent Claim
22 words
A topical aromatic releasing composition according to claim 4 which further comprises from about 0.1% to about 20% of a pharmaceutical active.
Claim 7
Dependent Claim
35 words
The composition of claim 5 wherein said pharmaceutical active is selected from the group consisting of antimicrobials, wound healing agents, vitamins, antiviral agents, analgesics, anti-inflammatory agents, antipuritics, antipyretics, anesthetic agents, antifungals, antimicrobials and mixtures thereof.
Claim 8
Dependent Claim
55 words
The composition of claim 5 wherein said antimicrobial drug is selected from the group consisting of β-lactam drugs, quinolone drugs, ciprofloxacin, norfloxacin, tetracycline, erythromycin, amikacin, triclosan, doxycycline, capreomycin, chlorhexidine, chlortetracycline, oxytetracycline, clindamycin, ethambutol, metronidazole, pentamidine, gentamicin, kanamycin, lineomycin, methacycline, methenamine, minocycline, neomycin, netilmicin, paromomycin, streptomycin, tobramycin, miconazole and amanfadine, pharmaceutically-acceptable salts thereof and mixtures thereof.
Claim 9
Dependent Claim
66 words
The composition of claim 5 wherein said anesthetic or antipruritic drug is selected from the group consisting of lidocaine, lidocaine hydrochloride, bupivacaine hydrochloride, chlorprocaine hydrochloride, dibucaine hydrochloride, etidocaine hydrochloride, mepivacaine hydrochloride, tetracaine, tetracaine hydrochloride, dyclonine hydrochloride and hexylcaine hydrochloride, benzocaine, benzyl alcohol, butamben picrate, camphor, camphorated metacresol, dibucaine, dibucaine hydrochloride, dimethisoquin hydrochloride, diphenhydramine hydrochloride, juniper tar, menthol, phenol, phenolate sodium, pramoxine hydrochloride, resorcinol and mixtures thereof.
Claim 10
Dependent Claim
34 words
The composition of claim 5 wherein said non-steroidal anti-inflammatory drug is selected from the group consisting of propionic acid derivatives, acetic acid derivatives, fenamic acid derivatives, biphenylcarboxylic acid derivatives, and oxicams and mixtures thereof.
Claim 11
Dependent Claim
48 words
The composition of claim 5 wherein said non-steroidal anti-inflammatory drug is a propionic acid derivatives selected from the group consisting of aspirin, acetaminophen, ibuprofen, naproxen, benoxaprofen, flurbiprofen, fenoprofen, fenbufen, ketoprofen, indoprofen, pirprofen, carprofen, oxaprozin, pranoprofen, miroprofen, tioxaprofen, suprofen, alminoprofen, tiaprofenic acid, fluprofen and bucloxic acid and mixtures thereof.
Claim 12
Dependent Claim
34 words
The composition of claim 5 wherein said vitamin is selected from the group consisting of Vitamin A, and derivatives thereof, ascorbic acid, Vitamin B, biotin, panthothenic acid, Vitamin D, Vitamin E and mixtures thereof.
Claim 13
Dependent Claim
33 words
The composition of claim 5 which further comprises an additional aromatic from the group consisting of benzaldehyde, citral, neral, decanal, aldehyde C-8, aldehyde C-9, aldehyde C-12, tolylaldehyde, 2,6-dimethyl-octanal and 2-dodecenal and mixtures thereof.
Claim 14
Dependent Claim
28 words
A method for treatment of cough, cold, cold-like and/or flu symptoms comprising administering a safe and effective amount of the topical aromatic releasing decongestant composition of claim 1.
Claim 15
Dependent Claim
28 words
A method for treatment of cough, cold, cold-like and/or flu symptoms comprising administering a safe and effective amount of the topical aromatic releasing decongestant composition of claim 2.
Claim 16
Dependent Claim
28 words
A method for treatment of cough, cold, cold-like and/or flu symptoms comprising administering a safe and effective amount of the topical aromatic releasing decongestant composition of claim 5.
Claim 17
Dependent Claim
28 words
A method for treatment of cough, cold, cold-like and/or flu symptoms comprising administering a safe and effective amount of the topical aromatic releasing decongestant composition of claim 8.
Claim 18
Dependent Claim
28 words
A method for treatment of cough, cold, cold-like and/or flu symptoms comprising administering a safe and effective amount of the topical aromatic releasing decongestant composition of claim 10.
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