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US5318014A Expired / Lapsed US ⏱️ 0.0 years remaining

Ultrasonic ablation/dissolution transducer

Assignee: Coraje Inc
•
Filing: 1992-09-14
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Granted: 1994-06-07
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Expires: 2012-09-14
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Abstract

Abstract Ultrasonic apparatus for clot dissolution includes a radiator for coupling ultrasonic waves and a piezoelectric crystal, connected with said radiator, for the intravascular generation of ultrasonic waves; said ultrasonic waves being propagated along a longitudinal axis of said piezoelectric crystal. A seed liquid is introduced proximate the radiator for promoting cavitation of intravascular fluid. In addition, enhancement of clot dissolution by chemical agents is shown to be significantly increased when combined with ultrasonic energy.

Inventors

  • 👤 Robert E. Carter

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:51
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/22; A61B17/22004; A61B17/22012; A61B17/2202; A61M; A61M37/00; A61M37/0092; A61B2017/22001; A61B2017/22002; A61B2017/22005; A61B2017/22007; A61B2017/22008; A61B2017/22021; A61B2017/22082

Claims Analysis

Total Claims: 25
Claim 1
Independent Claim 51 words
Ultrasonic apparatus for clot dissolution comprising: radiator means for coupling ultrasonic waves into intravascular fluids including clots, said radiator means being sized for intravascular insertion; means, connected with said radiator means, for the generation of ultrasonic waves; and separate means for promoting cavitation of the intravascular fluid proximate the radiator means.
Claim 2
Dependent Claim 51 words
Ultrasonic apparatus for clot dissolution comprising: radiator means for coupling ultrasonic waves into intravascular fluids including clots, said radiator means being sized for intravascular insertion; means, connected with said radiator means, for the generation of ultrasonic waves; and separate means for promoting cavitation of the intravascular fluid proximate the radiator means.
Claim 3
Dependent Claim 28 words
The apparatus according to claim 1 wherein the means for promoting cavitation comprises lumen means for introducing a seed fluid into the intravascular fluid proximate the radiator means.
Claim 4
Dependent Claim 33 words
The apparatus according to claim 1 further comprising a seed fluid and the means for causing cavitation comprises lumen means for introducing the seed fluid into the intravascular fluid proximate the radiator means.
Claim 5
Dependent Claim 18 words
The apparatus according to claim 3 wherein the seed fluid comprises an aqueous saline solution containing carbon dioxide.
Claim 6
Dependent Claim 27 words
The apparatus according to claim 4 wherein the carbon dioxide content in the aqueous saline solution is at most about 10 gms weight per liter of solution.
Claim 7
Dependent Claim 35 words
The apparatus according to claim 4 further comprising means for storing the aqueous saline solution at a pressure greater than atmospheric pressure and means for transferring the pressurized aqueous saline solution into the lumen means.
Claim 8
Dependent Claim 18 words
The apparatus according to claim 6 further comprising means, separate from said radiator means, for controlling clot dissolution.
Claim 9
Dependent Claim 30 words
The apparatus according to claim 7 wherein the means for controlling the clot dissolution rate comprises valve means for controlling the flow of the seed fluid into the lumen means.
Claim 10
Dependent Claim 34 words
The apparatus according to claim 7 wherein the means for controlling the clot dissolution rate comprises means for introducing a composition into the intravascular fluid proximate the radiator, said composition having clot dissolution activity.
Claim 11
Dependent Claim 101 words
Ultrasonic surgical apparatus for clot dissolution comprising: a catheter having at least one lumen therethrough and adapted for intravascular positioning; an ultrasonic transducer disposed in the catheter lumen at a distal end thereof, said ultrasonic transducer comprising: radiator means for coupling ultrasonic waves into clots; piezoelectric crystal means, connected with said radiator means, for generating ultrasonic waves; means for promoting cavitation of intravascular fluid proximate the radiator means; and power source means, disposed exterior to a proximate end of said catheter and electrically connected to said ultrasonic transducer through said catheter lumen, for causing said piezoelectric crystal to generate ultrasonic waves.
Claim 12
Dependent Claim 101 words
Ultrasonic surgical apparatus for clot dissolution comprising: a catheter having at least one lumen therethrough and adapted for intravascular positioning; an ultrasonic transducer disposed in the catheter lumen at a distal end thereof, said ultrasonic transducer comprising: radiator means for coupling ultrasonic waves into clots; piezoelectric crystal means, connected with said radiator means, for generating ultrasonic waves; means for promoting cavitation of intravascular fluid proximate the radiator means; and power source means, disposed exterior to a proximate end of said catheter and electrically connected to said ultrasonic transducer through said catheter lumen, for causing said piezoelectric crystal to generate ultrasonic waves.
Claim 13
Dependent Claim 28 words
The apparatus according to claim 10 wherein the means for promoting cavitation comprises lumen means for introducing a seed fluid into the intravascular fluid proximate the radiator means.
Claim 14
Dependent Claim 33 words
The apparatus according to claim 10 further comprising a seed fluid and the means for promoting cavitation comprises lumen means for introducing the seed fluid into the intravascular fluid proximate the radiator means.
Claim 15
Dependent Claim 18 words
The apparatus according to claim 12 wherein the seed fluid comprises an aqueous saline solution containing carbon dioxide.
Claim 16
Dependent Claim 27 words
The apparatus according to claim 13 wherein the carbon dioxide content in the aqueous saline solution is at most about 10 gms weight per liter of solution.
Claim 17
Dependent Claim 35 words
The apparatus according to claim 14 further comprising means for storing the aqueous saline solution at a pressure greater than atmospheric pressure and means for transferring the pressurized aqueous saline solution into the lumen means.
Claim 18
Dependent Claim 20 words
The apparatus according to claim 15 further comprising means, separate from said radiator mans, for controlling a clot dissolution rate.
Claim 19
Dependent Claim 29 words
The apparatus according to claim 16 wherein the means for controlling the clot dissolution comprises valve means for controlling the flow of the seed fluid into the lumen means.
Claim 20
Dependent Claim 35 words
The apparatus according to claim 16 wherein the means for controlling the clot dissolution rate comprises means for introducing a composition into the intravascular fluid proximate the radiator means, said composition having clot dissolution activity.
Claim 21
Independent Claim 55 words
A method for dissolving intravascular clots, said method comprising the steps of: introducing ultrasonic waves proximate intravascular clots comprising inserting a catheter, having an ultrasonic transducer on one end thereof, into a vessel and positioning the ultrasonic transducer proximate the intravascular clot; and providing means for promoting cavitation of intravascular fluid proximate the intravascular clots.
Claim 22
Independent Claim 55 words
A method for dissolving intravascular clots, said method comprising the steps of: introducing ultrasonic waves proximate intravascular clots comprising inserting a catheter, having an ultrasonic transducer on one end thereof, into a vessel and positioning the ultrasonic transducer proximate the intravascular clot; and providing means for promoting cavitation of intravascular fluid proximate the intravascular clots.
Claim 23
Dependent Claim 27 words
The method according to claim 19 wherein the step of providing mans for promoting cavitation comprises introducing a seed fluid into the intravascular fluid proximate the clot.
Claim 24
Dependent Claim 31 words
The method according to claim 19 wherein the step of providing means for promoting cavitation comprises introducing an aqueous saline solution, containing carbon dioxide, into the intravascular fluid, proximate the clots.
Claim 25
Dependent Claim 36 words
The method according to claim 19 wherein the step of providing means for promoting cavitation comprises introducing an aqueous saline solution, at a pressure greater than about 1 atmosphere, into the intravascular fluid proximate the clots.

References Cited (Backward Citations)

US4917095A Cited
US4931038A Cited
US5040537A Cited
US5018508A Cited
SU1671272A1 Cited
WO1991019529A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-06-06 1997-12-06 1998-06-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-06-06 2001-12-06 2002-06-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-06-06 2005-12-06 2006-06-07 $7700.00 Window Closed / Lapsed

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