Patent US5309649A successfully refreshed from Google Patents.
US5309649A
Expired / Lapsed
US
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Process and container for freeze drying under sterile conditions
Assignee: Roche Diagnostics GmbH
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Filing: 1992-09-03
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Granted: 1994-05-10
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Expires: 2012-09-03
Abstract
Abstract The present invention provides a process for freeze drying of especially biologically or pharmaceutical material under sterile conditions, wherein the material to be dried is introduced into a container the sides of which consist at least partly of a hydrophobic, porous, micro-organism-impermeable, water vapor-permeable membrane, the container is tightly closed and the material is subsequently freeze dried in the closed container under the usual conditions. The present invention also provides a container for freeze drying materials under sterile conditions, wherein the sides of the container consist at least partly of a hydrophobic, porous, germ-impermeable, water vapor-permeable membrane.
Inventors
- 👤 Thomas Bergmann
- 👤 Herbert Brustmann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 10:43
CPC Classifications
F; F26; F26B; F26B5/00; F26B5/04; F26B5/06; A; A01; A01N; A01N1/00; A01N1/10; A01N1/14; A01N1/146; A01N1/16; A01N1/162; A01N1/165; A61; A61L; A61L2202/00; A61L2202/10; A61L2202/18; A61L2202/181
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
58 words
The method of freeze drying biological or pharmaceutical material under sterile conditions, which comprises introducing said material into a container the sides of which consist at least partly of a hydrophobic, porous, microorganism-impermeable and water vapor-permeable membrane, tightly closing the container and freeze drying said material under sterile conditions inside the closed container in a non-sterile ambient environment.
Claim 2
Independent Claim
58 words
The method of freeze drying biological or pharmaceutical material under sterile conditions, which comprises introducing said material into a container the sides of which consist at least partly of a hydrophobic, porous, microorganism-impermeable and water vapor-permeable membrane, tightly closing the container and freeze drying said material under sterile conditions inside the closed container in a non-sterile ambient environment.
Claim 3
Dependent Claim
16 words
The method of claim 1, wherein the membrane has pores with a size of <0.5 μm.
Claim 4
Dependent Claim
16 words
The method of claim 2, wherein the membrane has pores with a size of <0.2 μm.
Claim 5
Dependent Claim
11 words
The method of claim 1, wherein said membrane is semi-permeable paper.
Claim 6
Dependent Claim
17 words
The method of claim 4, wherein the semi-permeable paper is made of cellulose or a cellulose derivative.
Claim 7
Dependent Claim
13 words
The method of claim 5, wherein a membrane of cellulose acetate is used.
Claim 8
Dependent Claim
15 words
The method of claim 1, wherein the membrane is a film of a polymer compound.
Claim 9
Dependent Claim
13 words
The method of claim 7, wherein the polymer compound is polytetrafluoroethylene or polypropylene.
Claim 10
Dependent Claim
17 words
The method of claim 1, wherein the container is in the form of a tube or bag.
Claim 11
Dependent Claim
26 words
The method of claim 9, wherein the tube or bag comprises a water-impermeable wall which is tightly connected with a further wall formed by the membrane.
Claim 12
Dependent Claim
20 words
The method of claim 1, wherein the container is a flask, ampule or vial which is closed with the membrane.
Claim 13
Dependent Claim
20 words
The method of claim 1, wherein the container is a trough which is tightly connected with the membrane as covering.
References Cited (Backward Citations)
GB995930A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-05-09 | 1997-11-08 | 1998-05-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-05-09 | 2001-11-08 | 2002-05-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-05-09 | 2005-11-08 | 2006-05-10 | $7700.00 | Window Closed / Lapsed |