US5282950A
Expired / Lapsed
US
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Electrochemical analysis system
Assignee: Roche Diagnostics GmbH
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Filing: 1992-07-14
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Granted: 1994-02-01
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Expires: 2012-07-14
Abstract
Abstract An electrochemical analysis system for analytical determination of a constituent of a sample includes a disposable analysis element and an evaluation unit. The disposable analysis element includes an isolating carrier with a sample application device for applying a sample thereto for analysis, and at least one sensor with a working electrode and a reference electrode for sensing electrical properties of the sample. The analysis element also includes a connection zone with connecting contacts which are connected to the electrodes via connecting leads. The evaluation unit includes an analysis element connector for electrically connecting to the connecting contacts of the analysis element, and a measuring and evaluation circuit for measuring electrical variation characteristics of the electrical properties sensed by the sensor on the analysis element. This circuit also converts a measured value into an analytical value, and includes a changeover device for changing over connection of an electrical power source with a current measuring device or a voltage measuring device to different connecting contacts of the analysis element.
Inventors
- 👤 Werner Dietze
- 👤 Hans-Peter Haar
- 👤 Wolfgang Obermeier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 23:12
CPC Classifications
G; G01; G01N; G01N27/00; G01N27/26; G01N27/28; G01N27/30; G01N27/327; G01N27/3271; G01N27/3273
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
236 words
An electrochemical analysis system for the analytical determination of a constituent of a sample, said system comprising: a disposable analysis element which includes an isolating carrier with a sample application means for applying a sample thereto for analysis, at least one sensor means with a working electrode and a reference electrode for sensing electrical properties of the sample on the sample application means, and a connection zone with element connecting contacts which are connected to the electrodes via connecting leads; and an evaluation unit which includes an analysis element connector means with unit contacts for electrically connecting to the element connecting contacts of said analysis element, and a measuring and evaluation circuit means for measuring electrical variation characteristics of the electrical properties sensed by the at least one sensor means on said analysis element and for converting a measured value into an analytical value, the measuring and evaluation circuit means including an electrical power source with a current measuring device, a voltage measuring device, and a changeover unit connected on one side to the electrical power source with said current measuring device and said voltage measuring device and another side of said changeover unit connected to said connector means with said unit contacts, said changeover unit comprising switching means for selectively connecting said electrical power source with said current measuring device and said voltage measuring device to different pairs of unit contacts in said connector means.
Claim 2
Dependent Claim
236 words
An electrochemical analysis system for the analytical determination of a constituent of a sample, said system comprising: a disposable analysis element which includes an isolating carrier with a sample application means for applying a sample thereto for analysis, at least one sensor means with a working electrode and a reference electrode for sensing electrical properties of the sample on the sample application means, and a connection zone with element connecting contacts which are connected to the electrodes via connecting leads; and an evaluation unit which includes an analysis element connector means with unit contacts for electrically connecting to the element connecting contacts of said analysis element, and a measuring and evaluation circuit means for measuring electrical variation characteristics of the electrical properties sensed by the at least one sensor means on said analysis element and for converting a measured value into an analytical value, the measuring and evaluation circuit means including an electrical power source with a current measuring device, a voltage measuring device, and a changeover unit connected on one side to the electrical power source with said current measuring device and said voltage measuring device and another side of said changeover unit connected to said connector means with said unit contacts, said changeover unit comprising switching means for selectively connecting said electrical power source with said current measuring device and said voltage measuring device to different pairs of unit contacts in said connector means.
Claim 3
Dependent Claim
16 words
An electrochemical analysis system according to claim 1, wherein the changeover unit incorporates a switching matrix.
Claim 4
Dependent Claim
24 words
An electrochemical analysis system according to claim 1, wherein the changeover unit, the voltage measuring device and the power source are integrated together monolithically.
Claim 5
Dependent Claim
64 words
An electrochemical analysis system according to claim 1, wherein said evaluation unit further includes discriminator means for determining an electrical resistance based on a voltage of the power source and a measured signal of the current measuring device, and for generating a fault signal based on whether the determined electrical resistance is at least one of below and above a predetermined resistance limit value.
Claim 6
Dependent Claim
47 words
An electrochemical analysis system according to claim 1, wherein the measuring and evaluation circuit further includes a microprocessor-controlled digital signal processing unit operatively connected to the current measuring device and the voltage measuring device so as to digitally control the electrical power source and the changeover unit.
Claim 7
Dependent Claim
27 words
An electrochemical analysis system according to claim 1, wherein each of the voltage measuring device and the current measuring device include means for determining complex signal components.
Claim 8
Dependent Claim
47 words
An electrochemical analysis system according to claim 1, wherein said evaluation unit further includes clocking means operatively connected to the changeover unit, the voltage measuring device and the current measuring device, for clocking the changeover unit, the voltage measuring device and the current measuring device in synchrony.
Claim 9
Dependent Claim
30 words
An electrochemical analysis system according to claim 1, wherein said evaluation unit further includes a sample and hold circuit operatively connected between the changeover unit and the voltage measuring device.
Claim 10
Dependent Claim
29 words
An electrochemical analysis system according to claim 1, wherein said evaluation unit further includes a sample and hold circuit operatively connected between the changeover unit and the measuring device.
Claim 11
Dependent Claim
203 words
An electrochemical analysis system for the analytical determination of a constituent of a sample, said system comprising: a disposable analysis element which includes an isolating carrier with a sample application means for applying a sample thereto for analysis, at least one sensor means with a working electrode and a reference electrode for sensing electrical properties of the sample on the sample application means, and a connection zone with connecting contacts which are connected to the electrodes via connecting leads, wherein at least one of the electrodes is connected to at least two of said connecting contacts via at least two connecting leads; and an evaluation unit which includes an analysis element connector means for electrically connecting to the connecting contacts of said analysis element, and a measuring and evaluation circuit means for measuring electrical variation characteristics of the electrical properties sensed by the at least one sensor means on said analysis element and for converting a measured value into an analytical value, the measuring and evaluation circuit means including a changeover means for changing over connection of at least one of an electrical power source with a current measuring device and a voltage measuring device to different connecting contacts of the analysis element.
Claim 12
Dependent Claim
203 words
An electrochemical analysis system for the analytical determination of a constituent of a sample, said system comprising: a disposable analysis element which includes an isolating carrier with a sample application means for applying a sample thereto for analysis, at least one sensor means with a working electrode and a reference electrode for sensing electrical properties of the sample on the sample application means, and a connection zone with connecting contacts which are connected to the electrodes via connecting leads, wherein at least one of the electrodes is connected to at least two of said connecting contacts via at least two connecting leads; and an evaluation unit which includes an analysis element connector means for electrically connecting to the connecting contacts of said analysis element, and a measuring and evaluation circuit means for measuring electrical variation characteristics of the electrical properties sensed by the at least one sensor means on said analysis element and for converting a measured value into an analytical value, the measuring and evaluation circuit means including a changeover means for changing over connection of at least one of an electrical power source with a current measuring device and a voltage measuring device to different connecting contacts of the analysis element.
Claim 13
Dependent Claim
23 words
An electrochemical analysis system according to claim 10, wherein the electrode to which the additional connecting lead is connected is the working electrode.
Claim 14
Dependent Claim
22 words
An electrochemical analysis system according to any one of claim 10, wherein the at least one sensor includes an additional auxiliary electrode.
Claim 15
Dependent Claim
25 words
An electrochemical analysis system according to claim 12, wherein a composition of the auxiliary electrode and a composition of the reference electrode are the same.
Claim 16
Dependent Claim
22 words
An electrochemical analysis system according to claim 11, wherein the working electrode is arranged between the reference electrode and the auxiliary electrode.
Claim 17
Dependent Claim
239 words
An electrochemical analysis system for the analytical determination of a constituent of a sample, comprising: disposable analysis elements, which comprise on an isolating carrier in a sample application zone at least one sensor with a working electrode and a reference electrode and in a connection zone connecting contacts, wherein the electrodes and the connecting contacts are connected via connecting leads and the electrical properties of the analysis elements measurable from the connecting contacts vary on contact with the sample in a manner characteristic of the analysis, and an evaluation unit, which comprises an analysis element connection with unit contacts for the electrical connection to the connecting contacts of the analysis elements, and a measuring and evaluation circuit for measuring the electrical variation characteristic of the analysis and conversion of the measured value into an analytical value, wherein the analysis element connection comprises a direct plug connector with two plugging zones, wherein the first plugging zone serves for the connection of the analysis element and the second plugging zone for the connection to plugs of a printed circuit board, which contains at least a part of the measuring and evaluation circuit, the plugging zones are connected to one another by contact spring parts, which comprise respectively outside contact springs in the first plugging zone for the contacting of the connecting contacts of the analysis element and inside contact springs for the contacting of the plugs of the printed circuit board.
Claim 18
Dependent Claim
239 words
An electrochemical analysis system for the analytical determination of a constituent of a sample, comprising: disposable analysis elements, which comprise on an isolating carrier in a sample application zone at least one sensor with a working electrode and a reference electrode and in a connection zone connecting contacts, wherein the electrodes and the connecting contacts are connected via connecting leads and the electrical properties of the analysis elements measurable from the connecting contacts vary on contact with the sample in a manner characteristic of the analysis, and an evaluation unit, which comprises an analysis element connection with unit contacts for the electrical connection to the connecting contacts of the analysis elements, and a measuring and evaluation circuit for measuring the electrical variation characteristic of the analysis and conversion of the measured value into an analytical value, wherein the analysis element connection comprises a direct plug connector with two plugging zones, wherein the first plugging zone serves for the connection of the analysis element and the second plugging zone for the connection to plugs of a printed circuit board, which contains at least a part of the measuring and evaluation circuit, the plugging zones are connected to one another by contact spring parts, which comprise respectively outside contact springs in the first plugging zone for the contacting of the connecting contacts of the analysis element and inside contact springs for the contacting of the plugs of the printed circuit board.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-01-31 | 1997-08-02 | 1998-02-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-01-31 | 2001-08-02 | 2002-02-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-01-31 | 2005-08-02 | 2006-02-01 | $7700.00 | Window Closed / Lapsed |