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US5276136A
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Laminin A chain polypeptides from the amino terminal globular domain
Assignee: University of Minnesota System
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Filing: 1992-06-08
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Granted: 1994-01-04
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Expires: 2012-06-08
Abstract
Abstract Polypeptides derived from domain VI of the amino terminal globule of the A chain of laminin and having sequences of at least about 5 amino acids, and which exhibit cell adhesion and cell spreading capacity are described. Medical devices such as prosthetic implants, percutaneous devices and cell culture substrates coated with a composition including the described polypeptides are also provided.
Inventors
- 👤 Amy P. N. Skubitz
- 👤 Leo T. Furcht
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:07
CPC Classifications
C; C12; C12N; C12N5/00; C12N5/0068; A; A61; A61L; A61L27/00; A61L27/28; A61L27/34; A61P; A61P43/00; C07; C07K; C07K14/00; C07K14/435; C07K14/78; C12N2533/00; C12N2533/50; C12N2533/52; Y; Y10; Y10S; Y10S977/00; Y10S977/70; Y10S977/734; Y10S977/735; Y10S977/737; Y10S977/738; Y10S977/813; Y10S977/84; Y10S977/895; Y10S977/902; Y10S977/904; Y10S977/915; Y10S977/923
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
10 words
A polypeptide of the formula: lys-leu-val-glu-his-val-pro-gly-arg-pro-val-arg-his-ala-gln-cys-arg [SEQ. ID. NO: 1].
Claim 2
Dependent Claim
10 words
A polypeptide of the formula: lys-leu-val-glu-his-val-pro-gly-arg-pro-val-arg-his-ala-gln-cys-arg [SEQ. ID. NO: 1].
Claim 3
Dependent Claim
10 words
A polypeptide of the formula: arg-pro-val-arg-his-ala-gln-cys-arg-val-cys-asp-gly-asn-ser-thr-asn-pro-arg-glu-arg-his [SEQ. ID. NO: 2].
Claim 4
Dependent Claim
10 words
A polypeptide of the formula: arg-pro-val-arg-his-ala-gln-cys-arg-val-cys-asp-gly-asn-ser-thr-asn-pro-arg-glu-arg-his [SEQ. ID. NO: 2].
Claim 5
Dependent Claim
10 words
A polypeptide of the formula: arg-tyr-lys-ile-thr-pro-arg-arg-gly-pro-pro-thr-tyr-arg [SEQ. ID. NO: 3].
Claim 6
Dependent Claim
10 words
A polypeptide of the formula: arg-tyr-lys-ile-thr-pro-arg-arg-gly-pro-pro-thr-tyr-arg [SEQ. ID. NO: 3].
Claim 7
Dependent Claim
10 words
A polypeptide of the formula: ala-arg-tyr-ile-arg-leu-arg-leu-gln-=arg-ile-arg-thr-leu [SEQ. ID. NO: 4].
Claim 8
Dependent Claim
10 words
A polypeptide of the formula: ala-arg-tyr-ile-arg-leu-arg-leu-gln-=arg-ile-arg-thr-leu [SEQ. ID. NO: 4].
Claim 9
Dependent Claim
10 words
A polypeptide of the formula: his-arg-asp-leu-arg-asp-leu-asp-pro-ile-val-thr-arg-arg-tyr-tyr-tyr-ser-ile-lys [SEQ. ID NO: 5].
Claim 10
Dependent Claim
10 words
A polypeptide of the formula: his-arg-asp-leu-arg-asp-leu-asp-pro-ile-val-thr-arg-arg-tyr-tyr-tyr-ser-ile-lys [SEQ. ID NO: 5].
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-01-03 | 1997-07-05 | 1998-01-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-01-03 | 2001-07-05 | 2002-01-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-01-03 | 2005-07-05 | 2006-01-04 | $7700.00 | Window Closed / Lapsed |