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US5276136A Expired / Lapsed US ⏱️ 0.0 years remaining

Laminin A chain polypeptides from the amino terminal globular domain

Assignee: University of Minnesota System
•
Filing: 1992-06-08
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Granted: 1994-01-04
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Expires: 2012-06-08
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Abstract

Abstract Polypeptides derived from domain VI of the amino terminal globule of the A chain of laminin and having sequences of at least about 5 amino acids, and which exhibit cell adhesion and cell spreading capacity are described. Medical devices such as prosthetic implants, percutaneous devices and cell culture substrates coated with a composition including the described polypeptides are also provided.

Inventors

  • 👤 Amy P. N. Skubitz
  • 👤 Leo T. Furcht

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 06:37
CPC Classifications
C; C12; C12N; C12N5/00; C12N5/0068; A; A61; A61L; A61L27/00; A61L27/28; A61L27/34; A61P; A61P43/00; C07; C07K; C07K14/00; C07K14/435; C07K14/78; C12N2533/00; C12N2533/50; C12N2533/52; Y; Y10; Y10S; Y10S977/00; Y10S977/70; Y10S977/734; Y10S977/735; Y10S977/737; Y10S977/738; Y10S977/813; Y10S977/84; Y10S977/895; Y10S977/902; Y10S977/904; Y10S977/915; Y10S977/923

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 10 words
A polypeptide of the formula: lys-leu-val-glu-his-val-pro-gly-arg-pro-val-arg-his-ala-gln-cys-arg [SEQ. ID. NO: 1].
Claim 2
Dependent Claim 10 words
A polypeptide of the formula: lys-leu-val-glu-his-val-pro-gly-arg-pro-val-arg-his-ala-gln-cys-arg [SEQ. ID. NO: 1].
Claim 3
Dependent Claim 10 words
A polypeptide of the formula: arg-pro-val-arg-his-ala-gln-cys-arg-val-cys-asp-gly-asn-ser-thr-asn-pro-arg-glu-arg-his [SEQ. ID. NO: 2].
Claim 4
Dependent Claim 10 words
A polypeptide of the formula: arg-pro-val-arg-his-ala-gln-cys-arg-val-cys-asp-gly-asn-ser-thr-asn-pro-arg-glu-arg-his [SEQ. ID. NO: 2].
Claim 5
Dependent Claim 10 words
A polypeptide of the formula: arg-tyr-lys-ile-thr-pro-arg-arg-gly-pro-pro-thr-tyr-arg [SEQ. ID. NO: 3].
Claim 6
Dependent Claim 10 words
A polypeptide of the formula: arg-tyr-lys-ile-thr-pro-arg-arg-gly-pro-pro-thr-tyr-arg [SEQ. ID. NO: 3].
Claim 7
Dependent Claim 10 words
A polypeptide of the formula: ala-arg-tyr-ile-arg-leu-arg-leu-gln-=arg-ile-arg-thr-leu [SEQ. ID. NO: 4].
Claim 8
Dependent Claim 10 words
A polypeptide of the formula: ala-arg-tyr-ile-arg-leu-arg-leu-gln-=arg-ile-arg-thr-leu [SEQ. ID. NO: 4].
Claim 9
Dependent Claim 10 words
A polypeptide of the formula: his-arg-asp-leu-arg-asp-leu-asp-pro-ile-val-thr-arg-arg-tyr-tyr-tyr-ser-ile-lys [SEQ. ID NO: 5].
Claim 10
Dependent Claim 10 words
A polypeptide of the formula: his-arg-asp-leu-arg-asp-leu-asp-pro-ile-val-thr-arg-arg-tyr-tyr-tyr-ser-ile-lys [SEQ. ID NO: 5].

References Cited (Backward Citations)

US4565789A Cited
EP0244688A2 Cited
US4870160A Cited
US4876332A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-01-03 1997-07-05 1998-01-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-01-03 2001-07-05 2002-01-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-01-03 2005-07-05 2006-01-04 $7700.00 Window Closed / Lapsed

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