US5269326A
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US
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Method for transvenously accessing the pericardial space via the right auricle for medical procedures
Assignee: Georgetown University
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Filing: 1991-10-24
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Granted: 1993-12-14
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Expires: 2011-10-24
Abstract
Abstract A method for placing various types of catheters into the pericardial space takes advantage of the fact that the right auricle is a thin-walled, low-pressure structure which can be readily penetrated without damaging the pericardium or the epicardium. The method avoids surgical trauma and the risks of general anesthesia and infection. A catheter is guided downstream through one of the venae cavae to the right atrium. Once inside the right atrium, the catheter is passed into the right auricle. The wall at the apex of the right auricle is then pierced to gain access to the pericardial space. The method can be used, for example, to provide electrical stimuli to the heart (e.g., for pacing, cardioversion, and defibrillation), to pick-up an ECG signal, to deliver pharmacologic agents to the heart, to improve vascularization, to remove pericardial fluid for analysis or pericardiocentesis, or to inject a radio-labelled or echo-sensitive dye into the pericardial space for precision fluid imaging.
Inventors
- 👤 Richard L. Verrier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:36
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/05; A61N1/0587; A61N1/18; A61N1/20; A61N1/30; A61N1/303; A61N1/306; A61P; A61P9/00; A61M; A61M2210/00; A61M2210/12; A61M2210/122; A61M25/00; A61M25/01
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
72 words
A method for transvenously accessing the pericardial space between a heart and its pericardium in preparation for a medical procedure, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; and (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle.
Claim 2
Independent Claim
72 words
A method for transvenously accessing the pericardial space between a heart and its pericardium in preparation for a medical procedure, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; and (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle.
Claim 3
Dependent Claim
17 words
The method of claim 1, wherein said one of the venae cavae is the superior vena cava.
Claim 4
Dependent Claim
19 words
The method of claim 2, wherein the catheter is introduced into the superior vena cava via a peripheral vein.
Claim 5
Dependent Claim
17 words
The method of claim 1, wherein said one of the venae cavae is the inferior vena cava.
Claim 6
Dependent Claim
19 words
The method of claim 4, wherein the catheter is introduced into the inferior vena cava via a peripheral vein.
Claim 7
Independent Claim
75 words
A method for transvenously delivering a pharmacologic agent to the heart, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle; and (d) introducing the pharmacologic agent into the pericardial space via said catheter.
Claim 8
Independent Claim
75 words
A method for transvenously delivering a pharmacologic agent to the heart, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle; and (d) introducing the pharmacologic agent into the pericardial space via said catheter.
Claim 9
Dependent Claim
43 words
The method of claim 6, further comprising the steps of: (e) passing an electrode through said catheter and into the pericardial space; and (f) delivering electrical energy to the heart muscle through said electrode to iontophoretically enhance the delivery of the pharmacologic agent.
Claim 10
Independent Claim
68 words
A method for monitoring electrical activity of the heart, said method comprising the following steps: (a) guiding an electrode downstream through one of the venae cavae to the right atrium; (b) guiding said electrode through the right atrium and into the right auricle; (c) inserting said electrode into the pericardial space by penetrating through the wall of the right auricle; and (d) detecting electrical energy with said electrode.
Claim 11
Independent Claim
68 words
A method for monitoring electrical activity of the heart, said method comprising the following steps: (a) guiding an electrode downstream through one of the venae cavae to the right atrium; (b) guiding said electrode through the right atrium and into the right auricle; (c) inserting said electrode into the pericardial space by penetrating through the wall of the right auricle; and (d) detecting electrical energy with said electrode.
Claim 12
Independent Claim
73 words
A method for delivering electrical stimuli to the heart, said method comprising the following steps: (a) guiding an electrode downstream through one of the venae cavae to the right atrium; (b) guiding said electrode through the right atrium and into the right auricle; (c) inserting said electrode into the pericardial space by penetrating through the wall of the right auricle; and (d) delivering the electrical stimuli to the heart muscle via said electrode.
Claim 13
Independent Claim
73 words
A method for delivering electrical stimuli to the heart, said method comprising the following steps: (a) guiding an electrode downstream through one of the venae cavae to the right atrium; (b) guiding said electrode through the right atrium and into the right auricle; (c) inserting said electrode into the pericardial space by penetrating through the wall of the right auricle; and (d) delivering the electrical stimuli to the heart muscle via said electrode.
Claim 14
Independent Claim
65 words
A method for performing pericardiocentesis, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle; and (d) withdrawing a fluid from the pericardial space.
Claim 15
Independent Claim
65 words
A method for performing pericardiocentesis, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle; and (d) withdrawing a fluid from the pericardial space.
Claim 16
Dependent Claim
76 words
A diagnostic method for use with the heart, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle; (d) sampling the pericardial fluid; and (e) analyzing said sample of the pericardial fluid for diagnostic purposes.
Claim 17
Dependent Claim
76 words
A diagnostic method for use with the heart, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle; (d) sampling the pericardial fluid; and (e) analyzing said sample of the pericardial fluid for diagnostic purposes.
Claim 18
Independent Claim
79 words
A method for diagnostic imaging of the heart, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle; (d) injecting an imaging fluid into the pericardial space; and (e) monitoring said imaging fluid with an external sensing device.
Claim 19
Independent Claim
79 words
A method for diagnostic imaging of the heart, said method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing the pericardial space with said catheter by penetrating through the wall of the right auricle; (d) injecting an imaging fluid into the pericardial space; and (e) monitoring said imaging fluid with an external sensing device.
Claim 20
Independent Claim
81 words
A method for transvenously performing a medical procedure on a heart, the method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing a pericardial space between the heart and its pericardium with said catheter by penetrating through the wall of the right auricle; and (d) performing the medical procedure on the heart via the pericardial space.
Claim 21
Independent Claim
81 words
A method for transvenously performing a medical procedure on a heart, the method comprising the following steps: (a) guiding a catheter downstream through one of the venae cavae to the right atrium; (b) guiding said catheter through the right atrium and into the right auricle; (c) accessing a pericardial space between the heart and its pericardium with said catheter by penetrating through the wall of the right auricle; and (d) performing the medical procedure on the heart via the pericardial space.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-12-13 | 1997-06-14 | 1997-12-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-12-13 | 2001-06-14 | 2001-12-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-12-13 | 2005-06-14 | 2005-12-14 | $7700.00 | Window Closed / Lapsed |