US4146029A — Self-powered implanted programmable medication sy…

Claim 1

Independent Claim 265 words

A self-powered programmable apparatus adapted to be totally received within a selected animal body, including human, for periodically dispensing selected medication therein according to a selected program coordinated with need while leaving the body ambulatory at all times, comprising: (a) a storage member mounted within the body for storing selected medication to be dispensed therein; (b) a micro size power source mounted within implanted housing means and having a useful working life in terms of at least several days; (c) miniaturized dispensing means mounted within implanted housing means and adapted to be operated under programmed electrical control to cause selected said medication to be discharged from the implanted storage member into said body; and (d) miniaturized programmable electrical control circuit means mounted within implanted housing means and connected to be energized by said power source, said electrical control means being adapted for performing control operations according to program instructions for actuation of said dispensing means, said control means embodying selectable and resettable plural program configurations, each program configuration providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and medical dispensation therefor, thereby providing in singular and plural programs assocated therewith a complex programming capability accommodating differential times and rates, means for extracting said data and means for applying said data to operate said dispensing means, said circuit means being set in a configuration corresponding to one of such programs and being adapted to actuate said dispensing means according to the selected program to dispense said medication within said body at times and rates determined by said program.

Claim 2

Dependent Claim 265 words

A self-powered programmable apparatus adapted to be totally received within a selected animal body, including human, for periodically dispensing selected medication therein according to a selected program coordinated with need while leaving the body ambulatory at all times, comprising: (a) a storage member mounted within the body for storing selected medication to be dispensed therein; (b) a micro size power source mounted within implanted housing means and having a useful working life in terms of at least several days; (c) miniaturized dispensing means mounted within implanted housing means and adapted to be operated under programmed electrical control to cause selected said medication to be discharged from the implanted storage member into said body; and (d) miniaturized programmable electrical control circuit means mounted within implanted housing means and connected to be energized by said power source, said electrical control means being adapted for performing control operations according to program instructions for actuation of said dispensing means, said control means embodying selectable and resettable plural program configurations, each program configuration providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and medical dispensation therefor, thereby providing in singular and plural programs assocated therewith a complex programming capability accommodating differential times and rates, means for extracting said data and means for applying said data to operate said dispensing means, said circuit means being set in a configuration corresponding to one of such programs and being adapted to actuate said dispensing means according to the selected program to dispense said medication within said body at times and rates determined by said program.

Claim 3

Dependent Claim 22 words

An apparatus as claimed in claim 1 wherein said circuit means further includes pacemaking circuit means operationally associated and functionally coordinated therewith.

Claim 4

Dependent Claim 36 words

An apparatus as claimed in claim 1 including means incorporating said logic stored control data arranged for being reprogrammed to selectively alter corresponding logic operating instructions and thereby provide the capability for simple to complex reprogramming.

Claim 5

Dependent Claim 22 words

An apparatus as claimed in claim 3 wherein said circuit means further includes pacemaking circuit means operationally associated and functionally coordinated therewith.

Claim 6

Dependent Claim 57 words

An apparatus as claimed in claim 3 wherein said evaluation, timing and associated circuit means include and operate with memory means to store selected said data from said sensing means and said memory in conjunction with said timing means provide the capability for evaluating said sensed body condition data selectively in real or historical or abstract time.

Claim 7

Dependent Claim 129 words

An apparatus as claimed in claim 1 including: (a) sensing means selectively placed within said body for producing sensed signals convertible to electrical data corresponding to a sensed condition within said body; (b) connector means within said body and connected to said sensing means for transferring such signals to said circuit means to be processed therein; and (c) within said circuit means data evaluation means connected through said connector means to said sensing means and adapted to receive selected data from said sensing means and convert such data into an electrically processable form and adapted for electrically evaluating such sensed data at selected times wherein actuation of said dispensing means is coordinated with evaluations of said data by said circuit means and as regulated by the selected said program.

Claim 8

Dependent Claim 20 words

An apparatus as claimed in claim 6 wherein said sensing means is operative both for said medication dispensing and pacemaking.

Claim 9

Dependent Claim 38 words

An apparatus as claimed in claim 1 including extracorporeal operator means operationally associated with said circuit means and operable extracorporeally to selectively select and set within said circuit means a particular configuration corresponding to a selected said program.

Claim 10

Dependent Claim 40 words

An apparatus as claimed in claim 8 wherein said circuit means includes means adapted to store selected said information in electrically retrievable form and said operator circuit means includes means to readout selected said information stored in said circuit means.

Claim 11

Dependent Claim 42 words

An apparatus as claimed in claim 8 wherein said operator means and circuit means are operatively associated through a rotary needle connector means adapted to electrically mate with and provide rotatable electrical hardwire connection with said circuit means for plural functions therein.

Claim 12

Dependent Claim 380 words

A self-powered programmable apparatus adapted to be totally received within a selected animal body, including human, for periodically evaluating selected internal physiological states of such body and for periodically dispensing selected medication substance therein according to such states while leaving the body ambulatory at all times, comprising: (a) a storage member mounted within the body for storing selected substance to be dispensed therein; (b) a micro size power source mounted within implanted means and having a useful working life in terms of at least several days; (c) miniaturized implanted dispensing means connected to receive said substance from said storage member and adapted to be operated at selected times and being adapted when so operated to cause selected said substance to be discharged from the storage member into said body; (d) sensing means selectively placed within said body for providing sensed signals convertible to electrical data corresponding to a sensed condition within said body; (e) connector means connected to said sensing means for transferring such signals for processing; (f) miniaturized electrical data evaluation and timing means mounted within implanted housing means and connected to be energized by said power source and comprising: (i) miniaturized electrical evaluation circuit means connected through said connector means to said sensing means and adapted to receive selected data from said sensing means and convert such data into an electrically processable form and adapted for electrically evaluating such sensed data; (ii) timing means operatively connected to said circuit means and providing both long term and short term electrical time base information thereto whereby said dispensing means is operated in coordination with selected evaluations; and (iii) associated circuit means responsive to external signal control enabling selected elements of said evaluation circuit and timing means to be selected and set in or to be reset to a selected operational program configuration selected from plural potential configurations therein, each program configuration providing a selection of logic stored digital control data accommodating for differential times and rates corresponding to a set of predetermined body conditions and needed substance dispensation therefor, thereby providing a complex programming capability determinative of the manner and mode of operation of said evaluation circuit and timing means; and (g) control means located external of said body for producing said signal control to select said program or programs.

Claim 13

Dependent Claim 380 words

A self-powered programmable apparatus adapted to be totally received within a selected animal body, including human, for periodically evaluating selected internal physiological states of such body and for periodically dispensing selected medication substance therein according to such states while leaving the body ambulatory at all times, comprising: (a) a storage member mounted within the body for storing selected substance to be dispensed therein; (b) a micro size power source mounted within implanted means and having a useful working life in terms of at least several days; (c) miniaturized implanted dispensing means connected to receive said substance from said storage member and adapted to be operated at selected times and being adapted when so operated to cause selected said substance to be discharged from the storage member into said body; (d) sensing means selectively placed within said body for providing sensed signals convertible to electrical data corresponding to a sensed condition within said body; (e) connector means connected to said sensing means for transferring such signals for processing; (f) miniaturized electrical data evaluation and timing means mounted within implanted housing means and connected to be energized by said power source and comprising: (i) miniaturized electrical evaluation circuit means connected through said connector means to said sensing means and adapted to receive selected data from said sensing means and convert such data into an electrically processable form and adapted for electrically evaluating such sensed data; (ii) timing means operatively connected to said circuit means and providing both long term and short term electrical time base information thereto whereby said dispensing means is operated in coordination with selected evaluations; and (iii) associated circuit means responsive to external signal control enabling selected elements of said evaluation circuit and timing means to be selected and set in or to be reset to a selected operational program configuration selected from plural potential configurations therein, each program configuration providing a selection of logic stored digital control data accommodating for differential times and rates corresponding to a set of predetermined body conditions and needed substance dispensation therefor, thereby providing a complex programming capability determinative of the manner and mode of operation of said evaluation circuit and timing means; and (g) control means located external of said body for producing said signal control to select said program or programs.

Claim 14

Dependent Claim 57 words

An apparatus as claimed in claim 11 wherein said evaluation, timing and associated circuit means include and operate with memory means to store selected said data from said sensing means and said memory in conjunction with said timing means provide the capability for evaluating said sensed body condition data selectively in real or historical or abstract time.

Claim 15

Dependent Claim 51 words

An apparatus as claimed in claim 11 wherein said associated circuit means includes switch contact means adapted to receive a needle connector for transmitting signal control through a hardwire connection and wherein said control means includes needle connector means enabling said signal control to pass therethrough to select a said program.

Claim 16

Dependent Claim 30 words

An apparatus as claimed in claim 1 wherein said storage member, dispensing means, sensing means and data evaluation and timing means are adapted for selectively dispensing plural sources of medication.

Claim 17

Dependent Claim 34 words

An apparatus as claimed in claim 11 wherein said storage member, sensing means, dispensing means and evaluation and timing means are adapted to storing, sensing the need for and dispensing doses of plural medications.

Claim 18

Dependent Claim 26 words

An apparatus as claimed in claim 15 wherein said dispensing means is adapted to dispensing said doses of plural medications to separate sites within said body.

Claim 19

Dependent Claim 16 words

An apparatus as claimed in claim 15 wherein said dispensing is according to plural sensing schedules.

Claim 20

Dependent Claim 47 words

An apparatus as claimed in claim 1 wherein said sensing means is adapted to sense and develop electrical signals corresponding to plural medical factors and said data evaluation and timing means is adapted to electrically evaluate said factors and dispense said substance medication according to such evaluation.

Claim 21

Dependent Claim 69 words

In an apparatus as claimed in claim 1 wherein said storage member stores a single medication, said dispensing member comprises plural dispensing means connected to a common said storage member and said data and evaluation timing means is adapted to evaluate the need for and to separately operate each such dispensing means to cause said medication to be dispensed independently through one or the other of said dispensing means.

Claim 22

Dependent Claim 46 words

In an apparatus as in claim 1 wherein said storage member, sensing means, dispensing means, data evaluation and housing means are adapted to sense the need for and to dispense a first medication on a regular timed basis and a second medication on a special basis.

Claim 23

Dependent Claim 43 words

An apparatus as claimed in claim 11 wherein said storage member, sensing means, dispensing means and evaluation and timing means are adapted to dispensing medication in a wide range of combinations of single and plural doses, medications, sensed conditions, sites, and timing schedules.

Claim 24

Dependent Claim 141 words

An apparatus as claimed in claim 11 adapted to dispense medication for prevention of recurrent tachycardias and arrhythmias and wherein said sensing means comprises a cardiac-type sensor and said data evaluation and timing means includes an amplifying circuit connected to said sensing means, a first QRS detector circuit connected to said amplifier, a second QRS period analysis and control value comparison circuit connected to said first QRS detector circuit, an R-R interval analysis and control value comparison circuit connected to said first QRS detector circuit and said QRS period analysis circuit, an evaluating logic circuitry connected to said second QRS period analysis and said R-R interval analysis circuit, a timing circuit connected to time said second QRS period circuit, said R-R interval analysis circuit and said logic evaluation circuit and wherein said dispensing means is controlled by said logic evaluation circuit.

Claim 25

Dependent Claim 351 words

A self-powered programmable apparatus adapted to be totally received within a selected animal body, including human, for periodically evaluating selected internal physiological states of such body and for periodically dispensing selected medication substance therein according to such states while leaving the body ambulatory at all times, comprising: (a) a storage member mounted within the body for storing selected substance to be dispensed therein; (b) a micro size power source mounted within implanted means and having a useful working life in terms of at least several days; (c) miniaturized dispensing means connected to receive said substance from said storage member and adapted to be operated at selected times and being adapted when so operated to cause selected said substance to be discharged from the storage member into said body; (d) sensing means selectively placed within said body for providing sensed signals convertible to electrical data corresponding to a sensed condition within said body; (e) connector means connected to said sensing means for transferring such signals for processing; (f) miniaturized electrical data evaluation and timing means and connected to be energized by said power source and comprising: (i) miniaturized electrical evaluation circuit means connected through said connector means to said sensing means and adapted to receive selected data from said sensing means and convert such data into an electrically processable form and adapted for electrically evaluating such sensed data; (ii) timing means operatively connected to said circuit means and providing electrical time base information thereto whereby said dispensing means is operated in coordination with selected evaluations; and (iii) associated circuit means responsive to external signal control enabling selected elements of said evaluation circuit and timing means to be set in a selected operational program configuration selected from plural potential configurations therein, said associated circuit means including switch contact means adapted to receive a needle connector for transmitting signal control reprogramming data through a hardwire connection and wherein said control means includes needle connector means enabling said signal control to pass therethrough to reprogram; and (g) control means located external of said body for producing said signal control to vary said program or programs.

Claim 26

Dependent Claim 351 words

A self-powered programmable apparatus adapted to be totally received within a selected animal body, including human, for periodically evaluating selected internal physiological states of such body and for periodically dispensing selected medication substance therein according to such states while leaving the body ambulatory at all times, comprising: (a) a storage member mounted within the body for storing selected substance to be dispensed therein; (b) a micro size power source mounted within implanted means and having a useful working life in terms of at least several days; (c) miniaturized dispensing means connected to receive said substance from said storage member and adapted to be operated at selected times and being adapted when so operated to cause selected said substance to be discharged from the storage member into said body; (d) sensing means selectively placed within said body for providing sensed signals convertible to electrical data corresponding to a sensed condition within said body; (e) connector means connected to said sensing means for transferring such signals for processing; (f) miniaturized electrical data evaluation and timing means and connected to be energized by said power source and comprising: (i) miniaturized electrical evaluation circuit means connected through said connector means to said sensing means and adapted to receive selected data from said sensing means and convert such data into an electrically processable form and adapted for electrically evaluating such sensed data; (ii) timing means operatively connected to said circuit means and providing electrical time base information thereto whereby said dispensing means is operated in coordination with selected evaluations; and (iii) associated circuit means responsive to external signal control enabling selected elements of said evaluation circuit and timing means to be set in a selected operational program configuration selected from plural potential configurations therein, said associated circuit means including switch contact means adapted to receive a needle connector for transmitting signal control reprogramming data through a hardwire connection and wherein said control means includes needle connector means enabling said signal control to pass therethrough to reprogram; and (g) control means located external of said body for producing said signal control to vary said program or programs.

Claim 27

Independent Claim 399 words

The method for periodically evaluating selected internal physiological states of an animal body, including human, and for periodically dispensing selected medication substance therein according to such states while leaving the body ambulatory at all times, comprising: (a) implanting a storage member within the body and storing therein a selected substance to be dispensed therefrom; (b) implanting a micro size power source having a useful working life in terms of at least several days; (c) implanting miniaturized dispensing means connected to receive said substance from said storage member and adapted to be operated at selected times to cause selected said substance to be discharged from the storage member into said body; (d) implanting sensing means for providing sensed signals convertible to electrical data corresponding to a sensed condition within said body; (e) implanting connector means connected to said sensing means for transferring such signals for processing; (f) implanting miniaturized electrical data evaluation and timing means and connected to be energized by said power source and comprising: (i) miniaturized electrical evaluation circuit means connected through said connector means to said sensing means and adapted to receive selected data from said sensing means and convert such data into an electrically processable form and adapted for electrically evaluating such sensed data; (ii) timing means operatively connected to said circuit means and providing electrical time base information thereto whereby said dispensing means is operated in coordination with selected evaluations; and (iii) associated circuit means responsive to external signal control enabling selected elements of said evaluation circuit and timing means to be set in a selected operational program configuration selected from plural potential configurations therein, each program configuration providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and needed substance dispensation therefor, thereby providing a complex programming capability determinative of the manner and mode of operation of said evaluation circuit and timing means; and (g) positioning control means external of said body for producing said signal control to select said program or programs; and (h) allowing said sensing means to operate, to produce signals corresponding to physiological states within the said body and allowing said substance to be dispensed to a selected site within the body on a schedule and program as determined by said data evaluation and timing means over a long period of time and by the program signal control established by said control means.

Claim 28

Independent Claim 399 words

The method for periodically evaluating selected internal physiological states of an animal body, including human, and for periodically dispensing selected medication substance therein according to such states while leaving the body ambulatory at all times, comprising: (a) implanting a storage member within the body and storing therein a selected substance to be dispensed therefrom; (b) implanting a micro size power source having a useful working life in terms of at least several days; (c) implanting miniaturized dispensing means connected to receive said substance from said storage member and adapted to be operated at selected times to cause selected said substance to be discharged from the storage member into said body; (d) implanting sensing means for providing sensed signals convertible to electrical data corresponding to a sensed condition within said body; (e) implanting connector means connected to said sensing means for transferring such signals for processing; (f) implanting miniaturized electrical data evaluation and timing means and connected to be energized by said power source and comprising: (i) miniaturized electrical evaluation circuit means connected through said connector means to said sensing means and adapted to receive selected data from said sensing means and convert such data into an electrically processable form and adapted for electrically evaluating such sensed data; (ii) timing means operatively connected to said circuit means and providing electrical time base information thereto whereby said dispensing means is operated in coordination with selected evaluations; and (iii) associated circuit means responsive to external signal control enabling selected elements of said evaluation circuit and timing means to be set in a selected operational program configuration selected from plural potential configurations therein, each program configuration providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and needed substance dispensation therefor, thereby providing a complex programming capability determinative of the manner and mode of operation of said evaluation circuit and timing means; and (g) positioning control means external of said body for producing said signal control to select said program or programs; and (h) allowing said sensing means to operate, to produce signals corresponding to physiological states within the said body and allowing said substance to be dispensed to a selected site within the body on a schedule and program as determined by said data evaluation and timing means over a long period of time and by the program signal control established by said control means.

Claim 29

Dependent Claim 225 words

A self-powered programmable dispensing apparatus adapted to be totally received within a selected animal body, including human, for altering a selected internal state of such body and for periodically dispensing selected substance therein while leaving the body ambulatory at all times, comprising: (a) storage means received within the body for storing selected substance to be dispensed therein; (b) a micro size power source received within the body and having a useful working life in terms of at least several hours; (c) miniaturized dispensing means received within the body and communicating with said storage means and being adapted when operated to discharge said substance from the storage means into said body; and (d) miniaturized electrical control means received within the body and connected to be energized by said power source and comprising: (i) miniaturized electrical circuit means adapted to be selectively set and reset to any of various operating modes for establishing a control program for operating said dispensing means, each of said operating modes providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and appropriate substance dispensation therefor, means for extracting said data and means for applying said data to operate said dispensing means thereby providing a complex program capability; and (ii) timing means operatively connected to said circuit means and providing electrical time base information thereto.

Claim 30

Dependent Claim 225 words

A self-powered programmable dispensing apparatus adapted to be totally received within a selected animal body, including human, for altering a selected internal state of such body and for periodically dispensing selected substance therein while leaving the body ambulatory at all times, comprising: (a) storage means received within the body for storing selected substance to be dispensed therein; (b) a micro size power source received within the body and having a useful working life in terms of at least several hours; (c) miniaturized dispensing means received within the body and communicating with said storage means and being adapted when operated to discharge said substance from the storage means into said body; and (d) miniaturized electrical control means received within the body and connected to be energized by said power source and comprising: (i) miniaturized electrical circuit means adapted to be selectively set and reset to any of various operating modes for establishing a control program for operating said dispensing means, each of said operating modes providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and appropriate substance dispensation therefor, means for extracting said data and means for applying said data to operate said dispensing means thereby providing a complex program capability; and (ii) timing means operatively connected to said circuit means and providing electrical time base information thereto.

Claim 31

Dependent Claim 340 words

A self-powered combined medicating and cardiac pacer apparatus adapted to be totally received within a selected animal body, including human, for periodically dispensing selected medication therein and pacing the heart thereof through electrodes connected thereto while leaving the body ambulatory at all times, comprising: (a) a storage member received within the body and adapted to store selected medication to be dispensed therein; (b) a micro size power source mounted within implanted housing means and having a useful working life in terms of at least several days; (c) miniaturized electrical control means adapted to both provide controlled electrical impulses on electrode means for heart pacing purposes and electrical control for the operation of dispensing means, selectable and resettable circuit means within said control means providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and medication dispensation therefor, thereby providing in singular and plural programs associated therewith a complex programming capability, means for extracting said data and means for applying said data to operate said dispensing means and pace said heart according to the program mode in which said program circuit means has been set; (d) miniaturized dispensing means connected to said storage member and adapted to be operated by said control means to cause said medication to be discharged from the storage member into said body; (e) electrode means adapted to be connected to the heart of said body and having a connection to said control means for receiving electrical impulses for evaluation to pace said heart in coordination with dispensing of said medication; and (f) selectable and resettable circuit means within said control means providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and medication dispensation therefor, thereby providing in singular and plural programs associated therewith a complex programming capability, means for extracting said data and means for applying said data to operate said dispensing means and heart pacing means according to the program mode in which said program circuit means has been set.

Claim 32

Dependent Claim 340 words

A self-powered combined medicating and cardiac pacer apparatus adapted to be totally received within a selected animal body, including human, for periodically dispensing selected medication therein and pacing the heart thereof through electrodes connected thereto while leaving the body ambulatory at all times, comprising: (a) a storage member received within the body and adapted to store selected medication to be dispensed therein; (b) a micro size power source mounted within implanted housing means and having a useful working life in terms of at least several days; (c) miniaturized electrical control means adapted to both provide controlled electrical impulses on electrode means for heart pacing purposes and electrical control for the operation of dispensing means, selectable and resettable circuit means within said control means providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and medication dispensation therefor, thereby providing in singular and plural programs associated therewith a complex programming capability, means for extracting said data and means for applying said data to operate said dispensing means and pace said heart according to the program mode in which said program circuit means has been set; (d) miniaturized dispensing means connected to said storage member and adapted to be operated by said control means to cause said medication to be discharged from the storage member into said body; (e) electrode means adapted to be connected to the heart of said body and having a connection to said control means for receiving electrical impulses for evaluation to pace said heart in coordination with dispensing of said medication; and (f) selectable and resettable circuit means within said control means providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and medication dispensation therefor, thereby providing in singular and plural programs associated therewith a complex programming capability, means for extracting said data and means for applying said data to operate said dispensing means and heart pacing means according to the program mode in which said program circuit means has been set.

Claim 33

Dependent Claim 268 words

A self-powered combined medication dispensing and electrically stimulating apparatus adapted to be totally received within a selected animal body, including human, for periodically dispensing selected substance therein and electrically stimulating a selected organ thereof through electrodes connected thereto while leaving the body ambulatory at all times, comprising: (a) storage means received within the body for storing selected substance to be dispensed therein for treating said body; (b) a micro size power source mounted within implanted housing means and having a useful working life in terms of at least several days; (c) miniaturized electrical control means adapted to both provide controlled electrical impulses on electrode means for organ electrical stimulating purposes and electrical control for the operation of dispensing means; (d) miniaturized dispensing means connected to said storage means and adapted to be operated by said control means to cause said substance to be discharged from storage means into said body; (e) electrode means adapted to be connected to a selected organ of said body and having a connection to said control means for receiving electrical impulses to electrically stimulate said organ in coordination with dispensing of said substance; and (f) selectable and resettable program circuit means within said control means providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and substance dispensation therefor, thereby providing in singular and plural programs associated therewith a complex programming capability, means for extracting said data and means for applying said data to operate said dispensing means and stimulate said organ according to the program mode in which said program circuit means has been set.

Claim 34

Dependent Claim 268 words

A self-powered combined medication dispensing and electrically stimulating apparatus adapted to be totally received within a selected animal body, including human, for periodically dispensing selected substance therein and electrically stimulating a selected organ thereof through electrodes connected thereto while leaving the body ambulatory at all times, comprising: (a) storage means received within the body for storing selected substance to be dispensed therein for treating said body; (b) a micro size power source mounted within implanted housing means and having a useful working life in terms of at least several days; (c) miniaturized electrical control means adapted to both provide controlled electrical impulses on electrode means for organ electrical stimulating purposes and electrical control for the operation of dispensing means; (d) miniaturized dispensing means connected to said storage means and adapted to be operated by said control means to cause said substance to be discharged from storage means into said body; (e) electrode means adapted to be connected to a selected organ of said body and having a connection to said control means for receiving electrical impulses to electrically stimulate said organ in coordination with dispensing of said substance; and (f) selectable and resettable program circuit means within said control means providing a selection of logic stored digital control data corresponding to a set of predetermined body conditions and substance dispensation therefor, thereby providing in singular and plural programs associated therewith a complex programming capability, means for extracting said data and means for applying said data to operate said dispensing means and stimulate said organ according to the program mode in which said program circuit means has been set.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	1982-03-26	1982-09-25	1983-03-27	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	1986-03-26	1986-09-25	1987-03-27	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	1990-03-26	1990-09-25	1991-03-27	$7700.00	Window Closed / Lapsed

Self-powered implanted programmable medication system and method

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