Patent US4650501A successfully refreshed from Google Patents.
Patent US5267940A successfully refreshed from Google Patents.
US5267940A
Expired / Lapsed
US
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Cardiovascular flow enhancer and method of operation
Assignee: Tulane University
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Filing: 1991-05-06
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Granted: 1993-12-07
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Expires: 2011-05-06
Abstract
Abstract An implanted cardiovascular assist pump is connected with the proximal descending thoracic aorta. The pump inlet is connected with the aorta at substantially the site of the first pressure/flow node from the heart. The pump outlet is connected at substantially the site of the last pressure/flow antinode before the heart. Control of pump speed varies blood flow through the pump. As a fail-safe mechanism, a pump shunt flow path is provided, through one of a variety of disclosed structures.
Inventors
- 👤 Peter V. Moulder
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 16:53
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61M; A61M60/00; A61M60/10; A61M60/122; A61M60/126; A61M60/152; A61M60/20; A61M60/205; A61M60/216; A61M60/226; A61M60/232; A61M60/40; A61M60/403; A61M60/408; A61M60/411; A61M60/50; A61M60/508; A61M60/515; A61M60/538; A61M60/546; A61M60/80; A61M60/802; A61M60/833; A61M60/855; A61M60/861; A61M60/871; A61M60/873; A61M60/89; A61M60/894; A61M60/896; A61M2205/00; A61M2205/33; A61M2205/3303; A61M2205/3331; A61M2205/3334; A61M2205/3337; A61M2205/82; A61M2205/8237; A61M2205/8243; A61M39/00; A61M39/22; A61M39/227; A61M39/228; A61M60/148
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
101 words
A method of implanting a cardiovascular flow enhancer comprising the steps of: providing an implantable centrifugal pump having an inlet and an outlet; providing an inlet conduit; providing an outlet conduit; connecting the inlet conduit with the pump inlet and with the descending thoracic aorta at substantially the site of the pressure node for blood from the heart to receive blood from the descending thoracic aorta and direct blood to the pump; and connecting the outlet conduit with the pump outlet and with the descending thoracic aorta at a point downstream from the inlet connection to discharge blood into the aorta.
Claim 2
Independent Claim
101 words
A method of implanting a cardiovascular flow enhancer comprising the steps of: providing an implantable centrifugal pump having an inlet and an outlet; providing an inlet conduit; providing an outlet conduit; connecting the inlet conduit with the pump inlet and with the descending thoracic aorta at substantially the site of the pressure node for blood from the heart to receive blood from the descending thoracic aorta and direct blood to the pump; and connecting the outlet conduit with the pump outlet and with the descending thoracic aorta at a point downstream from the inlet connection to discharge blood into the aorta.
Claim 3
Dependent Claim
41 words
The method of implanting a cardiovascular flow enhancer as claimed in claim 1 wherein the outlet conduit is connected with the descending thoracic aorta at substantially the last blood flow and pressure antinode before the heart of the descending thoracic aorta.
Claim 4
Dependent Claim
31 words
The method of implanting a cardiovascular flow enhancer as claimed in claim 1 in which the pump is located above the diaphragm in the lower left hemithorax of the posterior chest.
Claim 5
Dependent Claim
28 words
The method of implanting a cardiovascular flow enhancer as claimed in claim 1 in which the pump is located in the upper left hemithorax of the posterior chest.
Claim 6
Independent Claim
123 words
A method of implanting a cardiovascular flow enhancer comprising the steps of: providing an implantable centrifugal pump having an inlet and an outlet; providing an inlet conduit; providing an inlet conduit; providing an outlet conduit; connecting the inlet conduit with the pump inlet and with the descending thoracic aorta at substantially the site of the pressure node for blood from the heart to receive blood from the aorta and direct blood to the pump; and connecting the outlet conduit with the pump outlet and with the descending thoracic aorta at a point downstream from the inlet connection to discharge blood into the aorta; providing an alternative flow path in shunt with the pump to provide an emergency blood flow path around the pump.
Claim 7
Independent Claim
123 words
A method of implanting a cardiovascular flow enhancer comprising the steps of: providing an implantable centrifugal pump having an inlet and an outlet; providing an inlet conduit; providing an inlet conduit; providing an outlet conduit; connecting the inlet conduit with the pump inlet and with the descending thoracic aorta at substantially the site of the pressure node for blood from the heart to receive blood from the aorta and direct blood to the pump; and connecting the outlet conduit with the pump outlet and with the descending thoracic aorta at a point downstream from the inlet connection to discharge blood into the aorta; providing an alternative flow path in shunt with the pump to provide an emergency blood flow path around the pump.
Claim 8
Dependent Claim
27 words
The method of implanting a cardiovascular flow enhancer as claimed in claim 5 wherein a section of the thoracic aorta is connected in shunt with the pump.
Claim 9
Dependent Claim
70 words
The method of implanting a cardiovascular flow enhancer as claimed in claim 5 further comprising providing a controllable occluder operatively associated with the alternate flow path, the occluder being operable to minimize blood flow through the flow path in shunt with the pump during normal operation of the pump and to allow greater blood flow through the shunt conduit when blood flow through the pump falls below a minimum level.
Claim 10
Dependent Claim
67 words
The method of implanting a cardiovascular flow enhancer as claimed in claim 5 wherein the alternate flow path comprises an expandable graft conduit having an inner diameter permitting minimal blood flow through the shunt conduit when the pump is in normal operation, the expandable graft conduit being expandable to allow greater blood flow through the conduit when blood flow through the pump falls below a minimum level.
Claim 11
Dependent Claim
59 words
The method of implanting a cardiovascular flow enhancer as claimed in claim 5 wherein the alternate flow path includes a check valve to prevent back flow through the alternate flow path, and wherein the check valve is openable to allow blood flow through the alternate flow path when pressure upstream of the check valve reaches a predetermined maximum level.
Claim 12
Independent Claim
74 words
A method of implanting a cardiovascular flow enhancer comprising the steps of: providing a centrifugal pump having an inlet and an outlet; connecting the pump inlet to receive blood from the descending thoracic aorta from a site at substantially the first quiescent section of the descending thoracic aorta downstream from the brachiocephalic arteries; and connecting the pump outlet to discharge blood to the descending thoracic aorta at a point downstream from the inlet connection.
Claim 13
Independent Claim
74 words
A method of implanting a cardiovascular flow enhancer comprising the steps of: providing a centrifugal pump having an inlet and an outlet; connecting the pump inlet to receive blood from the descending thoracic aorta from a site at substantially the first quiescent section of the descending thoracic aorta downstream from the brachiocephalic arteries; and connecting the pump outlet to discharge blood to the descending thoracic aorta at a point downstream from the inlet connection.
Claim 14
Independent Claim
56 words
A method of implanting a cardiovascular flow enhancer comprising the steps of: providing a centrifugal pump having an inlet and an outlet; connecting the pump inlet to receive blood from the proximal descending thoracic aorta; and connecting the pump outlet to discharge blood to the descending thoracic aorta at a point downstream from the inlet connection.
Claim 15
Independent Claim
56 words
A method of implanting a cardiovascular flow enhancer comprising the steps of: providing a centrifugal pump having an inlet and an outlet; connecting the pump inlet to receive blood from the proximal descending thoracic aorta; and connecting the pump outlet to discharge blood to the descending thoracic aorta at a point downstream from the inlet connection.
Claim 16
Dependent Claim
42 words
The method of implanting a cardiovascular flow enhancer as claimed in claim 11 wherein the pump inlet is connected to receive blood from a site about one to twelve centimeters downstream from the juncture of the left subclavian artery and the aorta.
Claim 17
Independent Claim
60 words
A method of improving cardiovascular performance comprising the steps of: providing a centrifugal pump having an inlet and an outlet; connecting the pump inlet to receive blood from the first pressure and flow node of the descending thoracic aorta; and connecting the pump outlet to discharge blood to the descending thoracic aorta at a point downstream of the first connection.
Claim 18
Independent Claim
60 words
A method of improving cardiovascular performance comprising the steps of: providing a centrifugal pump having an inlet and an outlet; connecting the pump inlet to receive blood from the first pressure and flow node of the descending thoracic aorta; and connecting the pump outlet to discharge blood to the descending thoracic aorta at a point downstream of the first connection.
Claim 19
Dependent Claim
88 words
The method of improving cardiovascular performance of claim 13 further comprising: providing an inlet conduit having one end in fluid communication with the pump inlet; providing an outlet conduit having one end in fluid communication with the pump outlet; connecting the other end of the inlet conduit to the descending thoracic aorta substantially at the first nodal point; and connecting the other end of the outlet conduit to the descending thoracic aorta at a point downstream of the connection of the inlet conduit to the descending thoracic aorta.
Claim 20
Dependent Claim
51 words
The method of improving cardiovascular performance of claim 14 further comprising providing an inlet chamber in fluid connection with the pump inlet and the inlet conduit, an outlet chamber in fluid communication with the outlet conduit and the pump outlet, and a housing holding the pump, inlet chamber and outlet chamber.
Claim 21
Dependent Claim
35 words
The method of improving cardiovascular performance of claim 15 further comprising providing an emergency shunt flow path between the inlet chamber and the outlet chamber, the emergency shunt flow path being held within said housing.
Claim 22
Dependent Claim
22 words
The method of improving cardiovascular performance of claim 15 further comprising providing a drive motor within the housing to drive the pump.
Claim 23
Dependent Claim
34 words
The method of improving cardiovascular performance of claim 13 further comprising the steps of: sensing physiological conditions of the subject; and varying pump speed in accordance with the sensed physiological conditions of the subject.
Claim 24
Dependent Claim
162 words
A cardiovascular flow enhancer comprising: a centrifugal pump having an inlet and an outlet; an inlet conduit having one end in fluid communication with the pump inlet; an outlet conduit having one end in fluid communication with the pump outlet; the centrifugal pump, inlet conduit and outlet conduit defining a primary blood flow path; and a parallel flow conduit extending between the inlet and outlet conduits to provide an emergency blood flow path for a level of blood flow when blood flow through the pump falls below a minimum level and to provide a secondary blood flow path for a lower level of blood flow during normal operation of the pump, the parallel flow conduit being in parallel with the primary blood flow path the cardiovascular flow enhancer further comprising a housing made of a biologically inert material within which the centrifugal pump and parallel flow conduit are held, said housing being configured and sized to be implanted in a living body.
Claim 25
Dependent Claim
162 words
A cardiovascular flow enhancer comprising: a centrifugal pump having an inlet and an outlet; an inlet conduit having one end in fluid communication with the pump inlet; an outlet conduit having one end in fluid communication with the pump outlet; the centrifugal pump, inlet conduit and outlet conduit defining a primary blood flow path; and a parallel flow conduit extending between the inlet and outlet conduits to provide an emergency blood flow path for a level of blood flow when blood flow through the pump falls below a minimum level and to provide a secondary blood flow path for a lower level of blood flow during normal operation of the pump, the parallel flow conduit being in parallel with the primary blood flow path the cardiovascular flow enhancer further comprising a housing made of a biologically inert material within which the centrifugal pump and parallel flow conduit are held, said housing being configured and sized to be implanted in a living body.
Claim 26
Dependent Claim
56 words
The cardiovascular flow enhancer of claim 19 further comprising a controllable occluder operatively associated with the parallel flow conduit to limit blood flow through the parallel flow conduit during normal operation of the pump and to allow greater blood flow through the parallel flow conduit when blood flow through the pump falls below a minimum level.
Claim 27
Dependent Claim
59 words
The cardiovascular flow enhancer of claim 19 wherein the parallel flow conduit is expandable and has an inner diameter permitting minimal blood flow through the shunt conduit when the pump is in normal operation, the parallel flow conduit being expandable to allow greater blood flow through the conduit when blood flow through the pump falls below a minimum level.
Claim 28
Dependent Claim
47 words
The cardiovascular flow enhancer of claim 19 further comprising a flap valve to limit blood flow through the parallel flow conduit, the flap valve being openable to allow blood flow through the parallel flow conduit when pressure upstream of the flap valve reaches a predetermined maximum level.
Claim 29
Dependent Claim
61 words
The cardiovascular flow enhancer of claim 19 wherein the inlet conduit defines an inlet chamber in fluid communication with the pump inlet and the outlet conduit defines an outlet chamber in fluid communication with the pump outlet, the inlet and outlet chambers being held within the housing and the parallel flow conduit extending between the inlet chamber and the outlet chamber.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-12-06 | 1997-06-07 | 1997-12-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-12-06 | 2001-06-07 | 2001-12-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-12-06 | 2005-06-07 | 2005-12-07 | $7700.00 | Window Closed / Lapsed |