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US5254594A Expired / Lapsed US ⏱️ 0.0 years remaining

Remedies for bone diseases

Assignee: Astellas Deutschland GmbH
•
Filing: 1992-04-08
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Granted: 1993-10-19
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Expires: 2012-04-08
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Abstract

Abstract Remedies for bone diseases comprising, as active ingredient, droloxifene or a salt thereof.

Inventors

  • 👤 Kazuaki Niikura
  • 👤 Yoshimitsu Nakajima
  • 👤 Yoshitada Notsu
  • 👤 Ryuji Ono
  • 👤 Osamu Nakayama

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:37
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/02; A61K31/025; A61K31/03; A61K31/13; A61K31/135; A61P; A61P19/00; A61P19/08; A61P19/10; A61P3/00; A61P3/02; A61P3/12; A61P3/14; A61P43/00; A61P5/00; A61P5/24; A61P5/30

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 33 words
A method of treating bone diseases characterized by abnormalities in bone metabolism comprising administering to a patient suffering from bone disease a therapeutically effective amount of droloxifene or a pharmaceutically acceptable salt thereof.
Claim 2
Independent Claim 33 words
A method of treating bone diseases characterized by abnormalities in bone metabolism comprising administering to a patient suffering from bone disease a therapeutically effective amount of droloxifene or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim 22 words
A method according to claim 1, wherein droloxifene is administered in an amount of from 1 mg to 100 mg per day.
Claim 4
Dependent Claim 29 words
A method according to claim 1, wherein the bone disease is selected from the group consisting of osteoporosis, Paget's bone disease, bone dissolution, malignant hypercalcemia and chronic articular rheumatism.

References Cited (Backward Citations)

US4206234A Cited
US4623660A Cited
EP0054168A1 Cited
US5047431A Cited
US4729999A Cited
US4894373A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-10-18 1997-04-19 1997-10-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-10-18 2001-04-19 2001-10-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-10-18 2005-04-19 2005-10-19 $7700.00 Window Closed / Lapsed

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