US5237997A
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Method of continuous measurement of blood pressure in humans
Assignee: Vectron Gesellschaft fuer Technologieentwicklung und Systemforschung mbH
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Filing: 1989-03-09
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Granted: 1993-08-24
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Expires: 2009-03-09
Abstract
Abstract In a process for continuous measurement of blood pressure, the mean blood essure is derived from the measured pulse wave duration. The other blood pressure parameters are obtained by combination with an optoelectrical determination of blood volume density in a typical manner at the ear lobes. An initial individual basic calibration of the blood pressure values is carried out by a conventional method. In addition, a continuous automatic optoelectronic post-calibration is carried out. The measuring sensors are preferably a pair of ear clips and ECG electrodes or a photoelectric sensor. The method can be used to particular advantage in prevention and diagnosis.
Inventors
- 👤 Waldemar Greubel
- 👤 Albrecht A. C. von Muller
- 👤 Hubertus von Stein
- 👤 Rudolf Wieczorek
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 19:17
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/02; A61B5/021; A61B5/02108; A61B5/02125; A61B5/022; A61B5/0225; A61B5/02255; A61B5/026; A61B5/0285; A61B5/68; A61B5/6801; A61B5/6813; A61B5/6814; A61B5/6815; A61B5/6816; A61B5/72; A61B5/7203; A61B5/7207; A61B5/7214
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
293 words
A method of continuously measuring blood pressure in humans, and permanently measuring a pulse-wave running time of every pulse wave of a pateint's body, comprising the steps of: determining one of three blood pressure values comprising systolic, diastolic or mean blood pressure by measuring the pulse-wave running time; fixing an ear pulse measuring instrument to the patient's ear lobe and using the ear pulse measuring instrument to measure the pulse-wave running time between the patient's heart and the ear lobe; converting the pulse-wave running time into blood pressure values by using a calibration curve specific of each patient, which indicates the pulse-wave running time as a function method for measuring the blood pressure in order to establish this calibration curve; continuously determining an arterial blood volume density proportional to the blood pressure by means of an output signal of the ear pulse measuring instrument; determining the blood pressure using the output signal of the ear pulse measuring instrument after the output signal has been calibrated by comparing it with the blood-pressure measuring process according to Riva-Rocci; continuously recalibrating the output signal of the ear pulse measuring instrument in order to take into account vasomotoric and other regulations within the body, with the continuous recalibration step performed by electronic means permanently correlating the blood pressure value determined by measuring the pulse-wave running time to the respective output signal of the ear pulse measuring instrument, and thus permanently recalibrating the output signal of the ear pulse measuring instrument as a whole into blood pressure values; providing the patient's other ear lobe with a second ear pulse measuring instrument having an output signal; and comparing the output signals of the two pulse measuring instruments with each other electronically in order to eliminate disturbances of various kinds.
Claim 2
Independent Claim
293 words
A method of continuously measuring blood pressure in humans, and permanently measuring a pulse-wave running time of every pulse wave of a pateint's body, comprising the steps of: determining one of three blood pressure values comprising systolic, diastolic or mean blood pressure by measuring the pulse-wave running time; fixing an ear pulse measuring instrument to the patient's ear lobe and using the ear pulse measuring instrument to measure the pulse-wave running time between the patient's heart and the ear lobe; converting the pulse-wave running time into blood pressure values by using a calibration curve specific of each patient, which indicates the pulse-wave running time as a function method for measuring the blood pressure in order to establish this calibration curve; continuously determining an arterial blood volume density proportional to the blood pressure by means of an output signal of the ear pulse measuring instrument; determining the blood pressure using the output signal of the ear pulse measuring instrument after the output signal has been calibrated by comparing it with the blood-pressure measuring process according to Riva-Rocci; continuously recalibrating the output signal of the ear pulse measuring instrument in order to take into account vasomotoric and other regulations within the body, with the continuous recalibration step performed by electronic means permanently correlating the blood pressure value determined by measuring the pulse-wave running time to the respective output signal of the ear pulse measuring instrument, and thus permanently recalibrating the output signal of the ear pulse measuring instrument as a whole into blood pressure values; providing the patient's other ear lobe with a second ear pulse measuring instrument having an output signal; and comparing the output signals of the two pulse measuring instruments with each other electronically in order to eliminate disturbances of various kinds.
Claim 3
Dependent Claim
40 words
Method according to claim 1, characterised in that recalibration is carried out in that for certain constant blood pressure values the corresponding measurement signals are recorded and the blood pressure values corrected on the basis of alterations of these signals.
Claim 4
Dependent Claim
80 words
A method according to claim 1, further including the steps of: before the beginning of the continuous blood-pressure measurement, measuring the systolic and diastolic blood pressure values according to the Riva-Rocci method; calculating a pressure difference Δp from the measured systolic and diastolic blood pressure values; and correlating the pressure difference Δp to the difference Δi of the output signal corresponding to he diastolic value and the output signal corresponding to the systolic value of the ear pulse measuring instrument.
Claim 5
Dependent Claim
41 words
A method according to claim 1 further including the step of before the beginning of the continuous blood-pressure measurement, measuring the pulse-wave running time depending on several blood pressure values in order to establish the calibration curve specific of the patient.
Claim 6
Dependent Claim
54 words
A method according to claim 1 further including the step of using for measuring the pulse-wave running time a photo-electric sensor, which is placed on an area of the skin at the patient's chest or back which is near the heart and is supplied with blood by an intercostal artery close to the heart.
Claim 7
Dependent Claim
23 words
A method according to claim 1 further including the step of using ECG electrodes over the heart to measure the pulse-wave running time.
Claim 8
Dependent Claim
31 words
A method according to claim 1 further including the step of using for measuring the pulse-wave running time a miniature microphone fixed over the heart to sense a first cardiac sound.
Claim 9
Dependent Claim
37 words
A method according to claim 1 wherein the fixing step comprises using a pulsed infra-red light diode to send light through the ear lobe and that the transmission of the ear lobe is measured by a photodiode.
Claim 10
Dependent Claim
37 words
A method according to claim 8 further including the step of avoiding influences due to variable oxygen saturation of the blood by choosing a wave length of IR-light near an isometric point for the infra-red light diode.
Claim 11
Dependent Claim
50 words
A method according to claim 1, further including the steps of: receiving the two measurement signals of the two pulse measuring instruments with a coincidence circuit; and suppressing with the coincidence circuit all signals not measured at both ear lobes at the same time and thus rating them as artefacts.
Claim 12
Dependent Claim
19 words
A method according to claim 1 further including the step of continuously taking the body-temperature at the ear lobe.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-08-23 | 1997-02-22 | 1997-08-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-08-23 | 2001-02-22 | 2001-08-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-08-23 | 2005-02-22 | 2005-08-24 | $7700.00 | Window Closed / Lapsed |