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US5228438A Expired / Lapsed US ⏱️ 0.0 years remaining

Implantable pacemaker including means and method of terminating a pacemaker-mediated tachycardia during rate adaptive pacing

Assignee: Pacesetter Inc
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Filing: 1991-10-08
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Granted: 1993-07-20
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Expires: 2011-10-08
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Abstract

Abstract An atrial tracking dual-chamber pacemaker and method of use thereof for terminating a pacemaker-mediated tachycardia (PMT). The pacemaker includes means for determining whether the present heart rate exceeds a tachycardia reference rate, and if so, whether a PMT-indicating sequence of a tracked P-wave, including a retrograde P-wave followed by a V-pulse, occurs repetitiously for at least a predetermined number of cardiac cycles. The pacemaker includes means for measuring the interval between a P-wave and a V-pulse (PVI) and sets the PVI to 250 milliseconds when the measured value is less than 250 milliseconds. The pacemaker issues a PMT-terminating timed atrial pulse which is timed from a retrograde P-wave by a time equal to the PVI, plus a delay of about 25-100 milliseconds. In the event the atrial pulse fails to terminate the PMT, the process is repeated after a fixed number of cardiac cycles has occurred. An alternate embodiment includes determining a ventricular escape interval (VEI) which is equal to the AEI plus the PVI. Upon the delivery of the timed atrial pulse, the pacemaker changes to the VDD mode of operation, and immediately upon the occurrence of the following V-pulse which is a VEI displaced from the prior pulse, the pacemaker reverts to the DDD mode of operation.

Inventors

  • 👤 Stuart W. Buchanan

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 23:03
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/362; A61N1/3621; A61N1/3622

Claims Analysis

Total Claims: 50
Claim 1
Independent Claim 130 words
An implantable pacemaker including means for terminating a pacemaker-mediated tachycardia (PMT) comprising: detection means within said implantable pacemaker for detecting heart rate and for detecting P-waves and V-pulses and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of said prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between said P-wave and said V-pulse of each cardiac cycle comprising a P-V interval (PVI), a time interval between successive V-pulses comprising a V-V interval, the detection means further comprising means for timing a timed atrial pulse from a detected P-wave occurring in a corresponding one of the cycles in the sequence of cardiac cycles; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse for terminating a PMT.
Claim 2
Dependent Claim 130 words
An implantable pacemaker including means for terminating a pacemaker-mediated tachycardia (PMT) comprising: detection means within said implantable pacemaker for detecting heart rate and for detecting P-waves and V-pulses and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of said prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between said P-wave and said V-pulse of each cardiac cycle comprising a P-V interval (PVI), a time interval between successive V-pulses comprising a V-V interval, the detection means further comprising means for timing a timed atrial pulse from a detected P-wave occurring in a corresponding one of the cycles in the sequence of cardiac cycles; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse for terminating a PMT.
Claim 3
Dependent Claim 23 words
The pacemaker of claim 1, wherein the stimulation means includes means for stimulating the atrium after the heart rate exceeds a prescribed rate.
Claim 4
Dependent Claim 29 words
The pacemaker of claim 2, wherein the stimulation includes means for stimulating the atrium after a P-wave followed by a V-pulse occurs successively in the sequence of cardiac cycles.
Claim 5
Dependent Claim 32 words
The pacemaker of claim 3, wherein the stimulation means includes means for stimulating the atrium after the occurrence of a prescribed number of successive V-V intervals in the sequence of cardiac cycles.
Claim 6
Dependent Claim 27 words
The pacemaker of claim 4, wherein the stimulation means includes means for stimulating the atrium with a timed atrial pulse when the PVI exceeds a prescribed amount.
Claim 7
Dependent Claim 20 words
The pacemaker of claim 5, wherein the timing means times the timed atrial pulse, a prescribed delay from said P-wave.
Claim 8
Dependent Claim 26 words
The pacemaker of claim 6, wherein the prescribed delay comprises the PVI plus a delay interval, such delay interval comprising a range of about 25-100 milliseconds.
Claim 9
Dependent Claim 13 words
The pacemaker of claim 7, wherein the prescribed amount comprises approximately 250 milliseconds.
Claim 10
Dependent Claim 58 words
The pacemaker of claim 7, wherein the implantable pacemaker further comprises means for providing an atrial escape interval (AEI), the AEI comprising the interval from a V-pulse to the following atrial pulse, wherein the AEI comprises a time interval ranging from 275-600 milliseconds, and wherein the PVI comprises approximately 100 milliseconds, for maintaining a corresponding ventricular pulsing rate.
Claim 11
Dependent Claim 30 words
The pacemaker of claim 9 wherein the stimulation means includes means for stimulating the atrium by a timed atrial pulse upon the occurrence of a prescribed number of V-V intervals.
Claim 12
Dependent Claim 15 words
The pacemaker of claim 10, wherein the prescribed number of V-V intervals comprises about 128.
Claim 13
Dependent Claim 17 words
The pacemaker of claim 1, wherein the P-wave detected by said detecting means comprises a retrograde P-wave.
Claim 14
Dependent Claim 166 words
An implantable pacemaker for terminating a pacemaker-mediated tachycardia (PMT) in a patient comprising: detection means within the implantable pacemaker for detecting P-waves and V-pulses, the P-waves including retrograde P-waves, and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of the prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between the P-wave and the V-pulse of each cardiac cycle comprising a P-V interval (PVI), said PVI also being adjustable to at least an original value and a prescribed value, the time interval between successive V-pulses comprising a V-V interval, said detection means further comprising means for timing a timed atrial pulse from a detected retrograde P-wave occurring in the sequence of cardiac cycles; means for determining the duration of the PVI and for adjusting the PVI to the prescribed value when the PVI is less than the prescribed value; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse for terminating a PMT.
Claim 15
Dependent Claim 166 words
An implantable pacemaker for terminating a pacemaker-mediated tachycardia (PMT) in a patient comprising: detection means within the implantable pacemaker for detecting P-waves and V-pulses, the P-waves including retrograde P-waves, and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of the prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between the P-wave and the V-pulse of each cardiac cycle comprising a P-V interval (PVI), said PVI also being adjustable to at least an original value and a prescribed value, the time interval between successive V-pulses comprising a V-V interval, said detection means further comprising means for timing a timed atrial pulse from a detected retrograde P-wave occurring in the sequence of cardiac cycles; means for determining the duration of the PVI and for adjusting the PVI to the prescribed value when the PVI is less than the prescribed value; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse for terminating a PMT.
Claim 16
Dependent Claim 13 words
The pacemaker of claim 13, wherein the prescribed value comprises approximately 250 milliseconds.
Claim 17
Dependent Claim 21 words
The pacemaker of claim 13, wherein the timing means times the timed atrial pulse a prescribed delay from said retrograde P-wave.
Claim 18
Dependent Claim 26 words
The pacemaker of claim 15, wherein the prescribed delay comprises the PVI plus a delay interval, such delay interval comprising a range of about 25-100 milliseconds.
Claim 19
Dependent Claim 38 words
The pacemaker of claim 16 including means for retaining prior PVI values; means for comparing consecutive PVI values to detect a change thereof; and means for adjusting the PVI to the original value when such change is detected.
Claim 20
Dependent Claim 59 words
The pacemaker of claim 16, wherein the implantable pacemaker includes the DDD and VDD modes of operation, the pacemaker further comprising means for pacing in the VDD mode at least immediately after the occurrence of the timed atrial pulse, and for pacing in the DDD mode upon the occurrence of a V-pulse immediately subsequent to the timed atrial pulse.
Claim 21
Dependent Claim 209 words
An implantable pacemaker for terminating a pacemaker-mediated tachycardia (PMT) in a patient, wherein the pacemaker includes DDD and VDD modes of operation, the pacemaker comprising: detection means within the implantable pacemaker for detecting P-waves and V-pulses, the P-waves including retrograde P-waves and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of the prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between the P-wave and the V-pulse of each cardiac cycle comprising a P-V interval (PVI), the time interval between successive V-pulses comprising a V-V interval, the time interval between successive V-V pulses with an A-pulse therebetween comprising a VEI interval, the time interval between a V-pulse and the following retrograde P-wave comprising an atrial escape interval (AEI); the prescribed sequence of cardiac cycles includes at least four cycles comprising a first, a second, a third and a fourth cycle, the four cycles occurring successively, wherein the detection means measures the V-V interval in the first and second cycles for comparison to a tachycardia recognition rate (TRR), and further measures the PVI in the second cycle for comparison to a prescribed value; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse, for terminating a PMT.
Claim 22
Dependent Claim 209 words
An implantable pacemaker for terminating a pacemaker-mediated tachycardia (PMT) in a patient, wherein the pacemaker includes DDD and VDD modes of operation, the pacemaker comprising: detection means within the implantable pacemaker for detecting P-waves and V-pulses, the P-waves including retrograde P-waves and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of the prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between the P-wave and the V-pulse of each cardiac cycle comprising a P-V interval (PVI), the time interval between successive V-pulses comprising a V-V interval, the time interval between successive V-V pulses with an A-pulse therebetween comprising a VEI interval, the time interval between a V-pulse and the following retrograde P-wave comprising an atrial escape interval (AEI); the prescribed sequence of cardiac cycles includes at least four cycles comprising a first, a second, a third and a fourth cycle, the four cycles occurring successively, wherein the detection means measures the V-V interval in the first and second cycles for comparison to a tachycardia recognition rate (TRR), and further measures the PVI in the second cycle for comparison to a prescribed value; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse, for terminating a PMT.
Claim 23
Dependent Claim 67 words
The pacemaker of claim 19, including means for timing the timed atrial pulse from a retrograde P-wave detected in the third cycle and wherein the time to the timed atrial pulse comprises the PVI plus a delay interval, such delay interval being in the range of about 25-100 milliseconds, and wherein the stimulation means stimulates the atrium by a timed atrial pulse occurring in the fourth cycle.
Claim 24
Dependent Claim 52 words
The pacemaker of claim 20, further comprising means for adjusting the AEI and the PVI, wherein the adjusting means adjusts the AEI in the fourth cycle in the range of approximately 275-600 milliseconds, and the PVI to approximately 100 milliseconds for maintaining the V-V interval in the range of about 275-700 milliseconds.
Claim 25
Dependent Claim 36 words
The pacemaker of claim 19 further comprising means for adjusting the PVI in the third cycle to a prescribed value when the PVI is less than the prescribed value, such prescribed value comprising approximately 250 milliseconds.
Claim 26
Dependent Claim 20 words
The pacemaker of claim 22, including means for pacing in the VDD mode immediately subsequent to the timed atrial pulse.
Claim 27
Dependent Claim 19 words
The pacemaker of claim 23, including means for pacing in the DDD mode upon termination of the fourth cycle.
Claim 28
Dependent Claim 208 words
An implantable pacemaker for terminating a pacemaker-mediated tachycardia (PMT) in a patient comprising: detection means within the implantable pacemaker for detecting P-waves and V-pulses, the P-waves including retrograde P-waves, and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of the prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between the P-wave and the V-pulse of each cardiac cycle comprising a P-V interval (PVI), the time interval between successive V-pulses comprising a V-V interval, the time interval between successive V-V pulses with an A-pulse therebetween comprising a VEI interval, the time interval between a V-pulse and the following retrograde P-wave comprising an atrial escape interval (AEI), the detection means further comprising means for timing a timed atrial pulse from a detected retrograde P-wave occurring in the sequence of cardiac cycles and for detecting the value of the AEI and the PVI in one cycle of the sequence of cardiac cycles and for timing a timed atrial pulse from a retrograde P-wave occurring in another one of the cycles in the sequence, and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse in still another one of the cycles in the sequence for terminating a PMT.
Claim 29
Dependent Claim 208 words
An implantable pacemaker for terminating a pacemaker-mediated tachycardia (PMT) in a patient comprising: detection means within the implantable pacemaker for detecting P-waves and V-pulses, the P-waves including retrograde P-waves, and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of the prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between the P-wave and the V-pulse of each cardiac cycle comprising a P-V interval (PVI), the time interval between successive V-pulses comprising a V-V interval, the time interval between successive V-V pulses with an A-pulse therebetween comprising a VEI interval, the time interval between a V-pulse and the following retrograde P-wave comprising an atrial escape interval (AEI), the detection means further comprising means for timing a timed atrial pulse from a detected retrograde P-wave occurring in the sequence of cardiac cycles and for detecting the value of the AEI and the PVI in one cycle of the sequence of cardiac cycles and for timing a timed atrial pulse from a retrograde P-wave occurring in another one of the cycles in the sequence, and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse in still another one of the cycles in the sequence for terminating a PMT.
Claim 30
Independent Claim 261 words
A method for terminating a PMT in a patient having an implanted pacemaker, said method comprising the steps of: (a) sensing a V-pulse followed by a P-wave in a plurality of successive cardiac cycles to thereby sense an atrial escape interval AEI; (b) sensing a P-wave followed by a V-pulse in a plurality of successive cardiac cycles to thereby sense a PVI; (c) sensing a first V-pulse followed by a second V-pulse in a plurality of successive cardiac cycles to thereby sense a V-V interval, the V-V interval comprising the elapsed time between the first V-pulse and the second V-pulse; (d) sensing if the plurality of successive cardiac cycles sensed in step (c) occurs at a rate in excess of a tachycardia reference rate (TRR); (e) sensing if the sequence of a P-wave followed by a V-pulse sensed in step (b) or a V-pulse followed by a P-wave sensed in step (a) continues repetitiously for a prescribed number of sequences; (f) sensing if the number of V-V intervals exceeds a prescribed number wherein the rate sensed in step (d) exceeds the TRR and wherein the sequence of P-waves and V-pulses sensed in step (e) continues repetitiously; (g) sensing if the PVI is less than a prescribed value and adjusting the PVI to the prescribed value when the PVI is less than the prescribed value; (h) stimulating the atrium with an atrial pulse timed from a P-wave, a prescribed delay, the delay comprising the PVI of step (g) plus a delay interval, the delay interval comprising a range of approximately 25-100 milliseconds.
Claim 31
Independent Claim 261 words
A method for terminating a PMT in a patient having an implanted pacemaker, said method comprising the steps of: (a) sensing a V-pulse followed by a P-wave in a plurality of successive cardiac cycles to thereby sense an atrial escape interval AEI; (b) sensing a P-wave followed by a V-pulse in a plurality of successive cardiac cycles to thereby sense a PVI; (c) sensing a first V-pulse followed by a second V-pulse in a plurality of successive cardiac cycles to thereby sense a V-V interval, the V-V interval comprising the elapsed time between the first V-pulse and the second V-pulse; (d) sensing if the plurality of successive cardiac cycles sensed in step (c) occurs at a rate in excess of a tachycardia reference rate (TRR); (e) sensing if the sequence of a P-wave followed by a V-pulse sensed in step (b) or a V-pulse followed by a P-wave sensed in step (a) continues repetitiously for a prescribed number of sequences; (f) sensing if the number of V-V intervals exceeds a prescribed number wherein the rate sensed in step (d) exceeds the TRR and wherein the sequence of P-waves and V-pulses sensed in step (e) continues repetitiously; (g) sensing if the PVI is less than a prescribed value and adjusting the PVI to the prescribed value when the PVI is less than the prescribed value; (h) stimulating the atrium with an atrial pulse timed from a P-wave, a prescribed delay, the delay comprising the PVI of step (g) plus a delay interval, the delay interval comprising a range of approximately 25-100 milliseconds.
Claim 32
Dependent Claim 51 words
The method of terminating a PMT in a patient, as set forth in claim 26, further comprising the steps of: (i) adjusting the AEI in the range of about 275-600milliseconds; and (j) adjusting the PVI to about 100 milliseconds for maintaining the V-V interval in the range of about 375-700 milliseconds.
Claim 33
Dependent Claim 63 words
The method of terminating a PMT in a patient, as set forth in claim 27, further comprising the step of: (k) indicating the termination of a PMT when either the ventricular rate determined from the V-V interval falls below a tachycardia reference rate or the P-wave followed by a V-pulse sequence has terminated or a V-pulse followed by a P-wave sequence has terminated.
Claim 34
Dependent Claim 35 words
The method of terminating a PMT in a patient, as set forth in claim 28, further comprising the steps of repeating the steps (a)-(k) when termination of a PMT is not indicated in step (k).
Claim 35
Dependent Claim 33 words
The method of terminating a PMT in a patient, as set forth in claim 29, further comprising the step of: (l) counting a prescribed number of V-V intervals prior to repeating steps (a)-(k).
Claim 36
Dependent Claim 22 words
The method of terminating a PMT in a patient, as set forth in claim 30, wherein the prescribed number comprises about 128.
Claim 37
Dependent Claim 26 words
The method of terminating a PMT in a patient, as set forth in claim 26, wherein the prescribed value of step (g) comprises about 250 milliseconds.
Claim 38
Dependent Claim 48 words
The method of terminating a PMT in a patient, as set forth in claim 26, wherein the implanted pacemaker includes the VDD mode of operation, the method further comprising the step of: (n) commencing the VDD mode of operation immediately after the timed atrial pulse of step (h).
Claim 39
Dependent Claim 53 words
The method of terminating a PMT in a patient, as set forth in claim 26, wherein the implanted pacemaker includes the DDD mode of operation, the method further comprising the step of commencing the DDD mode of operation upon the occurrence of the V-pulse immediately following the timed atrial pulse of step (h).
Claim 40
Dependent Claim 140 words
An implantable pacemaker including means for terminating a pacemaker-mediated tachycardia (PMT) comprising: detection means within said implantable pacemaker for detecting heart rate and for detecting P-waves and V-pulses and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of said prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between said P-wave and said V-pulse of each cardiac cycle comprising a P-V interval (PVI), a time interval between successive V-pulses comprising a V-V interval, the detection means further comprises means for timing a timed atrial pulse from a detected P-wave occurring in a corresponding one of the cycles in the sequence of cardiac cycles; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse for terminating a PMT when the heart rate exceeds approximately 100 pulses per minute.
Claim 41
Dependent Claim 140 words
An implantable pacemaker including means for terminating a pacemaker-mediated tachycardia (PMT) comprising: detection means within said implantable pacemaker for detecting heart rate and for detecting P-waves and V-pulses and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of said prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between said P-wave and said V-pulse of each cardiac cycle comprising a P-V interval (PVI), a time interval between successive V-pulses comprising a V-V interval, the detection means further comprises means for timing a timed atrial pulse from a detected P-wave occurring in a corresponding one of the cycles in the sequence of cardiac cycles; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse for terminating a PMT when the heart rate exceeds approximately 100 pulses per minute.
Claim 42
Dependent Claim 149 words
An implantable pacemaker including means for terminating a pacemaker-mediated tachycardia (PMT) comprising: detection means within said implantable pacemaker for detecting heart rate and for detecting P-waves and V-pulses and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of said prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between said P-wave and said V-pulse of each cardiac cycle comprising a P-V interval (PVI), a time interval between successive V-pulses comprising a V-V interval, the detection means further comprises means for timing a timed atrial pulse from a detected P-wave occurring in a corresponding one of the cycles in the sequence of cardiac cycles; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse for terminating a PMT when the number of successive V-V intervals in the sequence of cardiac cycles comprises a number ranging from 2-20.
Claim 43
Dependent Claim 149 words
An implantable pacemaker including means for terminating a pacemaker-mediated tachycardia (PMT) comprising: detection means within said implantable pacemaker for detecting heart rate and for detecting P-waves and V-pulses and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of said prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between said P-wave and said V-pulse of each cardiac cycle comprising a P-V interval (PVI), a time interval between successive V-pulses comprising a V-V interval, the detection means further comprises means for timing a timed atrial pulse from a detected P-wave occurring in a corresponding one of the cycles in the sequence of cardiac cycles; and stimulation means responsive to the detection means for stimulating the atrium by said timed atrial pulse for terminating a PMT when the number of successive V-V intervals in the sequence of cardiac cycles comprises a number ranging from 2-20.
Claim 44
Dependent Claim 231 words
An implantable pacemaker for terminating a pacemaker-mediated tachycardia (PMT) in a patient comprising: detection means within the implantable pacemaker for detecting P-waves and V-pulses, the P-waves including retrograde P-waves, and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of the prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between the P-wave and the V-pulse of each cardiac cycle comprising a P-V interval (PVI), said PVI also being adjustable to at least a first prescribed value and a second prescribed value, the time interval between successive V-pulses comprising a V-V interval; means for timing a timed atrial pulse a prescribed delay from a detected P-wave occurring in the sequence of cardiac cycles; means for determining the duration of the PVI and for adjusting the PVI to the first prescribed value when the PVI is less than the first prescribed value; and stimulation means responsive to the detection means for stimulating the atrium by atrial pulses, such atrial pulses comprising at least said timed atrial pulse, the time interval between a V-pulse followed by the atrial pulse which immediately follows the timed atrial pulse comprising an atrial escape interval (AEI), said AEI also being adjustable to a third prescribed value, and means for adjusting the PVI to the second prescribed value and for adjusting the AEI to the third prescribed value for maintaining the V-V interval.
Claim 45
Dependent Claim 231 words
An implantable pacemaker for terminating a pacemaker-mediated tachycardia (PMT) in a patient comprising: detection means within the implantable pacemaker for detecting P-waves and V-pulses, the P-waves including retrograde P-waves, and for detecting a prescribed sequence of cardiac cycles, each cardiac cycle of the prescribed sequence comprising a P-wave followed by a V-pulse, the time interval between the P-wave and the V-pulse of each cardiac cycle comprising a P-V interval (PVI), said PVI also being adjustable to at least a first prescribed value and a second prescribed value, the time interval between successive V-pulses comprising a V-V interval; means for timing a timed atrial pulse a prescribed delay from a detected P-wave occurring in the sequence of cardiac cycles; means for determining the duration of the PVI and for adjusting the PVI to the first prescribed value when the PVI is less than the first prescribed value; and stimulation means responsive to the detection means for stimulating the atrium by atrial pulses, such atrial pulses comprising at least said timed atrial pulse, the time interval between a V-pulse followed by the atrial pulse which immediately follows the timed atrial pulse comprising an atrial escape interval (AEI), said AEI also being adjustable to a third prescribed value, and means for adjusting the PVI to the second prescribed value and for adjusting the AEI to the third prescribed value for maintaining the V-V interval.
Claim 46
Dependent Claim 17 words
The pacemaker of claim 37, wherein the P-wave detected by said detecting means is a retrograde P-wave.
Claim 47
Dependent Claim 14 words
The pacemaker of claim 37, wherein the first prescribed value comprises approximately 250 milliseconds.
Claim 48
Dependent Claim 14 words
The pacemaker of claim 37, wherein the second prescribed value comprises approximately 100 milliseconds.
Claim 49
Dependent Claim 17 words
The pacemaker of claim 37, wherein the third prescribed value comprises a range of about 275-600 milliseconds.
Claim 50
Dependent Claim 26 words
The pacemaker of claim 37, wherein the prescribed delay comprises the PVI plus a delay interval, such delay interval comprising a range of about 25-100 milliseconds.

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