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US5214028A
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Lactoferrin hydrolyzate for use as an antibacterial agent and as a tyrosinase inhibition agent
Assignee: Morinaga Milk Industry Co Ltd
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Filing: 1990-12-27
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Granted: 1993-05-25
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Expires: 2010-12-27
Abstract
Abstract Lactoferrin hydrolyzates, having a decomposition rate between 6%-20% as measured by formol titration, for use as an antibacterial agent and which have remarkly more potent activity than unhydrolyzed lactoferrin; and lactoferrin hydrolyzates, having a decomposition rate between 4-50% as measured by formol titration, for use as a tyrosinase inhibition agent, are obtainable by conventional methods for hydrolysis with acids or enzymes, and are stable to heating.
Inventors
- 👤 Mamoru Tomita
- 👤 Kouzou Kawase
- 👤 Yoshitaka Tamura
- 👤 Mitsunori Takase
- 👤 Hiroshi Miyakawa
- 👤 Koji Yamauchi
- 👤 Hitoshi Saito
- 👤 Hiroaki Abe
- 👤 Seiichi Shimamura
- 👤 Susumu Kobayashi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 17:51
CPC Classifications
A; A61; A61Q; A61Q17/00; A61Q17/005; A01; A01N; A01N63/00; A01N63/10; A23; A23B; A23B2/00; A23B2/70; A23B2/725; A23B2/729; A23B2/762; A23J; A23J3/00; A23J3/30; A23J3/32; A23J3/34; A23J3/341; A23J3/343; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/40; A61K8/00; A61K8/18; A61K8/30; A61K8/64; A61Q19/00; A61Q19/02; A61K2800/00; A61K2800/74; A61K2800/78; A61K2800/782
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
32 words
A method of tyrosinase inhibition comprising administering an amount of lactoferrin hydrolyzate having a decomposition rate of 4-50% effective for the inhibition of tyrosinase to a human or animal in need thereof.
Claim 2
Independent Claim
32 words
A method of tyrosinase inhibition comprising administering an amount of lactoferrin hydrolyzate having a decomposition rate of 4-50% effective for the inhibition of tyrosinase to a human or animal in need thereof.
Claim 3
Independent Claim
28 words
A method of tyrosinase inhibition comprising mixing an amount of lactoferrin hydrolyzate having a decomposition rate of 4-50% effective for the inhibition of tyrosinase with a food product.
Claim 4
Independent Claim
28 words
A method of tyrosinase inhibition comprising mixing an amount of lactoferrin hydrolyzate having a decomposition rate of 4-50% effective for the inhibition of tyrosinase with a food product.
Claim 5
Dependent Claim
13 words
The method of claim 1 or 2, wherein said decomposition rate is 6-40%.
Claim 6
Independent Claim
33 words
A method for the treatment and prevention of bacterial infection comprising administering an antibacterially effective amount of lactoferrin hydrolyzate having a decomposition rate of 6-20% to a human or animal in need thereof.
Claim 7
Independent Claim
33 words
A method for the treatment and prevention of bacterial infection comprising administering an antibacterially effective amount of lactoferrin hydrolyzate having a decomposition rate of 6-20% to a human or animal in need thereof.
Claim 8
Independent Claim
29 words
A method for the treatment and prevention of bacterial infection comprising mixing an antibacterially effective amount of lactoferrin hydrolyzate having a decomposition rate of 6-20% with a food product.
Claim 9
Independent Claim
29 words
A method for the treatment and prevention of bacterial infection comprising mixing an antibacterially effective amount of lactoferrin hydrolyzate having a decomposition rate of 6-20% with a food product.
Claim 10
Dependent Claim
13 words
The method of claim 4 or 5, wherein said decomposition rate is 7-15%.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1996-05-24 | 1996-11-23 | 1997-05-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-05-24 | 2000-11-23 | 2001-05-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-05-24 | 2004-11-23 | 2005-05-25 | $7700.00 | Window Closed / Lapsed |