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US5209978A
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US
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Seamless soft capsule and production thereof
Assignee: Taisho Pharmaceutical Co Ltd
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Filing: 1991-10-10
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Granted: 1993-05-11
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Expires: 2011-10-10
Abstract
Abstract A soft capsule composed of a plurality of cells coalesced to each other and filling substances encapsulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least one of the other cells, and said capsule being seamless. The soft capsule can be produced by (a) preparing a plurality of composite jet streams each consisting of a stream of a film-forming liquid substance for forming a cell wall and within said stream of a film-forming liquid substance a single stream, or a plurality of independent streams, of a filling substance having flowability, the film-forming liquid substance in at least one of the composite jet streams being different from the film-forming liquid substance in at least one of the other composite jet streams, (b) advancing the plurality of composite jet streams in closely spaced relationship into and through a stream of a liquid medium substantially incapable of dissolving the film-forming liquid substance in the flowing direction of the liquid medium stream, (c) coalescing the adjacent composite jet streams to each other to form a single composite jet stream in the liquid medium stream, (d) cutting the single composite jet stream to a predetermined length successively from its leading end in the liquid medium stream, and (e) solidifying the cell walls of the resulting soft capsule.
Inventors
- 👤 Tadashi Kosaka
- 👤 Kazuki Omata
- 👤 Tatsuo Hashimoto
- 👤 Teruaki Yamazaki
- 👤 Kazuo Hayashi
- 👤 Tomiya Hosoi
- 👤 Kenichi Ikuta
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 07:46
CPC Classifications
A; A61; A61J; A61J3/00; A61J3/07; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2984
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
262 words
A process for producing a soft capsule composed of a plurality of cells coalesced to each other and filling substances encapsulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least a second of the cells, and said capsule being seamless, said method comprising: (a) preparing a plurality of parallel, side by side composite jet streams, each of said composite jet streams having a central longitudinal axis and forming one of said plurality of cells, each of said composite jet streams consisting of a stream of a film-forming liquid substance for forming a cell wall and, within and surrounded by said stream of a film-forming liquid substance, a single stream, or a plurality of independent streams, of a filling substance, the film-forming liquid substance in at least one of the composite jet streams being different from the film-forming liquid substance in at least one of the other composite jet streams, (b) advancing the plurality of composite jet streams, with their respective central longitudinal axes in a spaced and parallel relationship, into and through a liquid medium substantially incapable of dissolving the film-forming liquid substance, (c) coalescing the film-forming streams of adjacent composite jet streams to each other to form a unitary composite jet stream in the liquid medium, (d) cutting the unitary composite jet stream to a predetermined length successively from its leading end in the liquid medium and, (e) solidifying the cell walls of the resulting cut pieces to form the soft capsule.
Claim 2
Dependent Claim
262 words
A process for producing a soft capsule composed of a plurality of cells coalesced to each other and filling substances encapsulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least a second of the cells, and said capsule being seamless, said method comprising: (a) preparing a plurality of parallel, side by side composite jet streams, each of said composite jet streams having a central longitudinal axis and forming one of said plurality of cells, each of said composite jet streams consisting of a stream of a film-forming liquid substance for forming a cell wall and, within and surrounded by said stream of a film-forming liquid substance, a single stream, or a plurality of independent streams, of a filling substance, the film-forming liquid substance in at least one of the composite jet streams being different from the film-forming liquid substance in at least one of the other composite jet streams, (b) advancing the plurality of composite jet streams, with their respective central longitudinal axes in a spaced and parallel relationship, into and through a liquid medium substantially incapable of dissolving the film-forming liquid substance, (c) coalescing the film-forming streams of adjacent composite jet streams to each other to form a unitary composite jet stream in the liquid medium, (d) cutting the unitary composite jet stream to a predetermined length successively from its leading end in the liquid medium and, (e) solidifying the cell walls of the resulting cut pieces to form the soft capsule.
Claim 3
Dependent Claim
37 words
A soft capsule produced by the process of claim 1 wherein the wall of said one cell is adhered to the wall of said second cell to define an interface traversing the entire width of the capsule.
Claim 4
Dependent Claim
26 words
A soft capsule in accordance with claim 2 produced by said process using two of said composite jet streams and wherein said interface bisects said capsule.
Claim 5
Dependent Claim
31 words
A soft capsule produced by the process of claim 1 which is oblong in shape and has, in cross-section, one dimension equal to the corresponding dimension of one of said cells.
Claim 6
Dependent Claim
54 words
A soft capsule, triangular in cross-section, produced by the process of claim 1 utilizing three of said composite jet streams, said capsule consisting of three cells, each of said three cells being joined to the two other cells along an interface running from one triangular surface to a second triangular surface of said cross-section.
Claim 7
Dependent Claim
91 words
A unitary seamless capsule containing plural cells coalesced together, each of said cells containing a filling substance encapsulated by a cell wall completely surrounding the filling substance, the cell wall of at least one of the cells being formed of a material different from a material forming the wall of at least a second of said cells, said cell walls being melded together with each of said cell walls defining in part the outermost surface of said seamless capsule, said capsule having one cross-section cutting through all of said plural cells.
Claim 8
Dependent Claim
91 words
A unitary seamless capsule containing plural cells coalesced together, each of said cells containing a filling substance encapsulated by a cell wall completely surrounding the filling substance, the cell wall of at least one of the cells being formed of a material different from a material forming the wall of at least a second of said cells, said cell walls being melded together with each of said cell walls defining in part the outermost surface of said seamless capsule, said capsule having one cross-section cutting through all of said plural cells.
Claim 9
Dependent Claim
22 words
The unitary capsule of claim 6 wherein all of said plural cells are arranged in a linear array to define said cross-section.
Claim 10
Dependent Claim
22 words
The unitary capsule of claim 6 wherein all of said plural cells are arranged in a triangular array to define said cross-section.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-05-10 | 1996-11-09 | 1997-05-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-05-10 | 2000-11-09 | 2001-05-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-05-10 | 2004-11-09 | 2005-05-11 | $7700.00 | Window Closed / Lapsed |