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Method for the delivery of compositions to the ocular tissues

Assignee: Weill Medical College of Cornell University
•
Filing: 1991-04-26
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Granted: 1993-05-04
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Expires: 2011-04-26
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Abstract

Abstract Therapeutic compositions are administered to the ocular tissues by positioning a balloon catheter having an illuminating fiberoptic stylette therein in the retrobulbar or parabulbar space of a patient. After the catheter is properly positioned, the composition is sequentially injected at predetermined intervals over a period of time. A variety of compositions can be administered including corticosteroids, antibiotics, macular degeneration alleviating compositions and inflammation alleviating compositions. Such administration of the therapeutic composition sustains appropriate levels of the composition in the ocular tissues without inducing toxic effects in unaffected tissues.

Inventors

  • 👤 Harvey A. Lincoff

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 21:15
CPC Classifications
A; A61; A61F; A61F9/00; A61F9/0008; A61F9/0017; A61M; A61M25/00; A61M25/10

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 49 words
A method for administering a composition to the ocular tissues, comprising: positioning a balloon catheter in the retrobulbar space by expanding the balloon to maintain the position of the catheter in the retrobulbar space; and sequentially injecting through the catheter a predetermined amount of the composition at predetermined intervals.
Claim 2
Independent Claim 49 words
A method for administering a composition to the ocular tissues, comprising: positioning a balloon catheter in the retrobulbar space by expanding the balloon to maintain the position of the catheter in the retrobulbar space; and sequentially injecting through the catheter a predetermined amount of the composition at predetermined intervals.
Claim 3
Dependent Claim 32 words
The method according to claim 1, wherein said catheter includes an illuminating fiberoptic stylette and said positioning includes guiding said catheter into the retrobulbar space by observing said catheter using an ophthalmoscope.
Claim 4
Dependent Claim 12 words
The method according to claim 1, wherein the composition is a corticosteroid.
Claim 5
Dependent Claim 12 words
The method according to claim 1, wherein the composition is an antibiotic.
Claim 6
Dependent Claim 12 words
The method according to claim 1, wherein the composition alleviates macular degeneration.
Claim 7
Dependent Claim 11 words
The method according to claim 1, wherein the composition alleviates inflammation.
Claim 8
Independent Claim 49 words
A method for administering a composition to the ocular tissues, comprising: positioning a balloon catheter in the parabulbar space by expanding the balloon to maintain the position of the catheter in the parabulbar space; and sequentially injecting through the catheter a predetermined amount of the composition at predetermined intervals.
Claim 9
Independent Claim 49 words
A method for administering a composition to the ocular tissues, comprising: positioning a balloon catheter in the parabulbar space by expanding the balloon to maintain the position of the catheter in the parabulbar space; and sequentially injecting through the catheter a predetermined amount of the composition at predetermined intervals.
Claim 10
Dependent Claim 32 words
The method according to claim 7, wherein said catheter includes an illuminating fiberoptic stylette and said positioning includes guiding said catheter into the parabulbar space by observing said catheter using an ophthalmoscope.
Claim 11
Dependent Claim 12 words
The method according to claim 7, wherein the composition is a corticosteriod.
Claim 12
Dependent Claim 12 words
The method according to claim 7, wherein the composition is an antibiotic.
Claim 13
Dependent Claim 12 words
The method according to claim 7, wherein the composition alleviates macular degeneration.
Claim 14
Dependent Claim 11 words
The method according to claim 7, wherein the composition alleviates inflammation.

References Cited (Backward Citations)

US3788327A Cited
US3954110A Cited
US4299227A Cited
US4454151A Cited
US4820270A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-05-03 1996-11-02 1997-05-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-05-03 2000-11-02 2001-05-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-05-03 2004-11-02 2005-05-04 $7700.00 Window Closed / Lapsed

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