Patent FR834704A successfully refreshed from Google Patents.
Patent US5207226A successfully refreshed from Google Patents.
US5207226A
Expired / Lapsed
US
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Device and method for measurement of blood flow
Assignee: University of Minnesota System
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Filing: 1991-01-25
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Granted: 1993-05-04
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Expires: 2011-01-25
Abstract
Abstract A device and method for measuring fluid flow within a vessel having fluctuating elastic walls, such as, for example, an artery. The device includes a catheter; an internal stablizer or frame for establishing an invariant cross-section in the vessel wall; and a fluid velocity detecting system, such as, for example, a Doppler crystal transducer. The method for measuring includes the steps of stabilizing the vessel wall and measuring the velocity of fluid passing through the stabilized cross-section of the vessel wall. A method of treating and a method of diagnosing vascular disease by employing the device of this invention is also part of the invention.
Inventors
- 👤 Steven J. Bailin
- 👤 Robert F. Wilson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 22:32
CPC Classifications
A; A61; A61B; A61B8/00; A61B8/06; A61B8/12; A61B8/44; A61B8/4444; A61B8/445
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
105 words
A device, suitable for measuring fluid flow within a vessel characterized by generally tubular segments or elastic wall, each of the wall segments having an internal circumference which is normally fluctuating and defining a variable cross-section for the segment, the device comprising: a catheter having a distal end suitable for insertion into the means, carried by the catheter adjacent the distal end, for internally stabilizing by engaging the entire internal circumference of one of the segments in order to maintain a constant cross-sectional area of the segment; and means, carried by the catheter adjacent the distal end, for detecting fluid velocity within the engaged segment.
Claim 2
Independent Claim
105 words
A device, suitable for measuring fluid flow within a vessel characterized by generally tubular segments or elastic wall, each of the wall segments having an internal circumference which is normally fluctuating and defining a variable cross-section for the segment, the device comprising: a catheter having a distal end suitable for insertion into the means, carried by the catheter adjacent the distal end, for internally stabilizing by engaging the entire internal circumference of one of the segments in order to maintain a constant cross-sectional area of the segment; and means, carried by the catheter adjacent the distal end, for detecting fluid velocity within the engaged segment.
Claim 3
Dependent Claim
44 words
The device of claim 1, and wherein the means for stabilizing a segment of vessel wall comprises a reinforcement frame of rigidity and perimeter sufficient to engage the segment and secure a constant geometry and dimension without substantially obstructing fluid flow through the segment.
Claim 4
Dependent Claim
34 words
The device of claim 2 and wherein the reinforcement frame has a generally annular shape and is oriented with the axis of the annular frame substantially parallel to the longitudinal axis of the catheter.
Claim 5
Dependent Claim
39 words
The device of claim 3, and wherein the catheter is connected to the periphery of the annular structure and the means for measuring velocity includes at least one piezoelectric crystal transducer mounted on the catheter adjacent the annular structure.
Claim 6
Dependent Claim
20 words
The device of claim 1, and wherein the means for stabilizing includes a means for retracting the means for stabilizing.
Claim 7
Dependent Claim
36 words
The device of claim 5, and wherein the means for stabilizing comprises: a temperature transformable super-elastic material in a fine crystal structure; and wherein temperature transformation of the super elastic material retracts the means for stabilizing.
Claim 8
Dependent Claim
44 words
The device of claim 5, and wherein the means for stabilizing a portion of vessel wall includes: an inflatable torus connected to the catheter; a channel extending longitudinally within the catheter and continuing into the torus structure to provide fluid communication with the torus.
Claim 9
Dependent Claim
52 words
The device of claim 5, and wherein the means for stabilizing further comprises: a channel longitudinally extending within the catheter; and wherein the means for retracting comprises: a guide wire longitudinally slidable within the channel; and wherein pressure of the guide wire within the portion of the channel retracts the stabilizing means.
Claim 10
Dependent Claim
30 words
The device of claim 1, and wherein the means for measuring velocity include a single piezoelectric crystal transducer capable of ultrasonic velocity measurement by a pulsed Doppler flow measuring system.
Claim 11
Dependent Claim
32 words
The device of claim 1, and wherein the means for measuring flow include a pair of piezoelectric crystal transducers capable of ultrasonic velocity measurement by a continuous wave Doppler flow measuring system.
Claim 12
Dependent Claim
22 words
The device of claim 1, and wherein the means for detecting include an ultrasonic measurement by a multigating Doppler flow measuring system.
Claim 13
Dependent Claim
16 words
The device of claim 1, and further comprising: means for measuring pressure adjacent the distal end.
Claim 14
Dependent Claim
19 words
The device of claim 12, and wherein the means for measuring pressure comprises a hydraulic fluid pressure measurement system.
Claim 15
Dependent Claim
15 words
The device of claim 12, and wherein the means for measuring pressure include a micromanometer.
Claim 16
Dependent Claim
17 words
The device of claim 12, and wherein the means for measuring pressure comprises a solid state detector.
Claim 17
Dependent Claim
20 words
The device of claim 1 and further comprising: means for delivering a pharmaceutical or biological agent adjacent the distal end.
Claim 18
Dependent Claim
42 words
The device of claim 16 and wherein the means for delivering the pharmaceutical agent includes a longitudinal channel of the catheter extending between an outlet adjacent the distal end of the catheter and a fitting adjacent the proximal end of the catheter.
Claim 19
Dependent Claim
44 words
The device of claim 1, and wherein the means for stabilizing a portion of vessel wall includes a helical structure of resilient material and the helical structure is oriented such that the helical axis is substantially parallel to the longitudinal axis of the catheter.
Claim 20
Independent Claim
128 words
A method for measuring blood flow in an arterial vessel serving a selected section of vasculature, the method comprising the steps of: inserting the distal end of a catheter into the vessel, the catheter having means carried by the catheter adjacent the distal end for engaging the entire internal circumference of a tubular segment of the vessel in order to maintain a constant cross-section of the vessel segment, and having means, carried by the catheter adjacent the distal end, for detecting fluid velocity; stabilizing the cross-sectional area of a segment of the wall in the arterial vessel serving the section of pulmonary vasculature by engaging the entire internal circumference with the means for engaging; and measuring the velocity of blood flow passing within the stabilized portion of wall.
Claim 21
Independent Claim
128 words
A method for measuring blood flow in an arterial vessel serving a selected section of vasculature, the method comprising the steps of: inserting the distal end of a catheter into the vessel, the catheter having means carried by the catheter adjacent the distal end for engaging the entire internal circumference of a tubular segment of the vessel in order to maintain a constant cross-section of the vessel segment, and having means, carried by the catheter adjacent the distal end, for detecting fluid velocity; stabilizing the cross-sectional area of a segment of the wall in the arterial vessel serving the section of pulmonary vasculature by engaging the entire internal circumference with the means for engaging; and measuring the velocity of blood flow passing within the stabilized portion of wall.
Claim 22
Dependent Claim
25 words
The method of claim 19 wherein the vasculature is pulmonary vasculature and further comprising: advancing the stabilizer to the segment of wall to be stabilized.
Claim 23
Dependent Claim
16 words
The method of claim 20 and further comprising: withdrawing the stabilizing device subsequent to measuring flow.
Claim 24
Dependent Claim
23 words
The method of claim 20, wherein the measuring velocity of blood flow includes providing a piezoelectric transducer for ultrasonic Doppler measurement of velocity.
Claim 25
Dependent Claim
30 words
The method of claim 20 and further comprising the step of: computing the flow of blood based upon the flow velocity and the cross-sectional area within the stabilized wall segment.
References Cited (Backward Citations)
US3605726A
Cited
US3902501A
Cited
US4169464A
Cited
US4269198A
Cited
US4355643A
Cited
US4502488A
Cited
US4665911A
Cited
US4873989A
Cited
US4793825A
Cited
US4671295A
Cited
US4722347A
Cited
US4730619A
Cited
US4733669A
Cited
US4667678A
Cited
US4791935A
Cited
US4887996A
Cited
US4878898A
Cited
US4886059A
Cited
US4913642A
Cited
US5121749A
Cited
US4957110A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1996-05-03 | 1996-11-02 | 1997-05-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-05-03 | 2000-11-02 | 2001-05-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-05-03 | 2004-11-02 | 2005-05-04 | $7700.00 | Window Closed / Lapsed |