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US5200414A
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Methods for the treatment of cognitive disorders
Assignee: Glaxo Group Ltd
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Filing: 1992-07-27
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Granted: 1993-04-06
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Expires: 2012-07-27
Abstract
Abstract The invention relates to the use of certain compounds which act as antagonists of 5-hydroxytryptamine (5-HT) at 5-HT 3 receptors for the treatment of cognitive disorders such as attentional and memory deficits and dementia states.
Inventors
- 👤 Michael B. Tyers
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 20:43
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/41; A61K31/415; A61K31/44; A61K31/445; A61K31/46; A61K31/495; A61K31/50; A61K31/55
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
45 words
A method of improving cognition in a patient suffering from dementia or other cognitive disorder which comprises administering to the patient an effective amount of endo-N-(8-methyl-8-azabicyclooct-3-yl)-2,3-dihydro-3,3-dimethylindole-1-carboxamide, or a physiologically acceptable salt or solvate thereof, which compound acts as a 5-HT antagonist at 5-HT 3 receptors.
Claim 2
Independent Claim
45 words
A method of improving cognition in a patient suffering from dementia or other cognitive disorder which comprises administering to the patient an effective amount of endo-N-(8-methyl-8-azabicyclooct-3-yl)-2,3-dihydro-3,3-dimethylindole-1-carboxamide, or a physiologically acceptable salt or solvate thereof, which compound acts as a 5-HT antagonist at 5-HT 3 receptors.
References Cited (Backward Citations)
GB2125398A
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GB2153821A
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GB2169292A
Cited
EP0190920A2
Cited
US4624961A
Cited
EP0200444A2
Cited
GB2193633A
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US4845115A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-04-05 | 1996-10-05 | 1997-04-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-04-05 | 2000-10-05 | 2001-04-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-04-05 | 2004-10-05 | 2005-04-06 | $7700.00 | Window Closed / Lapsed |