US5198210A
Expired / Lapsed
US
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Cosmetic composition
Assignee: FD Management Inc
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Filing: 1991-10-21
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Granted: 1993-03-30
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Expires: 2011-10-21
Abstract
Abstract Novel pseudoceramides are defined, together with their synthesis and compositions comprising them for topical application to human skin, hair and nails.
Inventors
- 👤 Peter Critchley
- 👤 Desmond B. Hagan
- 👤 Susan E. Kirsch
- 👤 David T. Parrot
- 👤 Anthony V. Rawlings
- 👤 Ian R. Scott
- 👤 Anthony P. Taylor
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 13:14
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; C; C07; C07C; C07C235/00; C07C235/02; C07C235/04; C07C235/08; A61K8/68; A61Q; A61Q19/00; A61Q5/00; A61Q19/007; A61Q3/00
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
278 words
A composition suitable for topical application to skin, hair or nails, which comprises: (i) an amount of from 0.0001 to 20% by weight of a pseudoceramide having the structure (2): ##STR13## where R represents a linear or branched, saturated or unsaturated, hydroxylated or non-hydroxylated, phosphorylated or non-phosphorylated, sulphated or non-sulphated aliphatic hydrocarbon group having from 1 from 49 carbon atoms or the sub-group Y--O--(C a H b )--; R 1 represents a linear or branched, saturated or unsaturated, hydroxylated or non-hydroxylated, phosphorylated or non-phosphorylated, sulphated or non-sulphated aliphatic hydrocarbon group having from 1 to 28 carbon atoms; R 2 represents H, a sugar residue, a sulphate residue or a phosphate residue P i ; P i represents the group: ##STR14## R 3 represents H, or the sub group (3): ##STR15## X 1 , X 2 and X 3 each individually represent H, C 1-5 alkyl or C 1-5 hydroxyalkyl; Y represents H or a residue of a C 14-22 fatty acid having the structure (4): ##STR16## z represents --OH --OP i , --OSO 3 .sup.⊖ or an epoxy oxygen, a is an integer of from 7 to 49 b is an integer of from 10 to 98 c is 0 or an integer of from 1 to 4 d is 0 or 1 x is an integer of from 12 to 20 y is an integer of from 20 to 40 z is 0 or an integer of from 1 to 4 n is 0 or 1 m is 1 provided that when the R group has from 9 to 49 carbon atoms, then n+m is 1 or 2; and (ii) a cosmetically acceptable vehicle for the pseudoceramide.
Claim 2
Dependent Claim
278 words
A composition suitable for topical application to skin, hair or nails, which comprises: (i) an amount of from 0.0001 to 20% by weight of a pseudoceramide having the structure (2): ##STR13## where R represents a linear or branched, saturated or unsaturated, hydroxylated or non-hydroxylated, phosphorylated or non-phosphorylated, sulphated or non-sulphated aliphatic hydrocarbon group having from 1 from 49 carbon atoms or the sub-group Y--O--(C a H b )--; R 1 represents a linear or branched, saturated or unsaturated, hydroxylated or non-hydroxylated, phosphorylated or non-phosphorylated, sulphated or non-sulphated aliphatic hydrocarbon group having from 1 to 28 carbon atoms; R 2 represents H, a sugar residue, a sulphate residue or a phosphate residue P i ; P i represents the group: ##STR14## R 3 represents H, or the sub group (3): ##STR15## X 1 , X 2 and X 3 each individually represent H, C 1-5 alkyl or C 1-5 hydroxyalkyl; Y represents H or a residue of a C 14-22 fatty acid having the structure (4): ##STR16## z represents --OH --OP i , --OSO 3 .sup.⊖ or an epoxy oxygen, a is an integer of from 7 to 49 b is an integer of from 10 to 98 c is 0 or an integer of from 1 to 4 d is 0 or 1 x is an integer of from 12 to 20 y is an integer of from 20 to 40 z is 0 or an integer of from 1 to 4 n is 0 or 1 m is 1 provided that when the R group has from 9 to 49 carbon atoms, then n+m is 1 or 2; and (ii) a cosmetically acceptable vehicle for the pseudoceramide.
Claim 3
Dependent Claim
39 words
A composition according to claim 1 wherein R is at least 8 carbon atoms or is the subgroup Y--O--(C a H b )--, the group R 1 containing at least 8 carbon atoms and n+m is 1 or 2.
Claim 4
Dependent Claim
19 words
A method of treating skin, hair or nails which comprises applying topically thereto a composition according to claim 1.
Claim 5
Dependent Claim
12 words
A method according to claim 3 wherein the application is to skin.
Claim 6
Dependent Claim
19 words
A method of treating skin, hair or nails which comprises applying topically thereto a composition according to claim 2.
Claim 7
Dependent Claim
12 words
A method according to claim 5 wherein the application is to skin.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-03-29 | 1996-09-28 | 1997-03-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-03-29 | 2000-09-28 | 2001-03-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-03-29 | 2004-09-28 | 2005-03-30 | $7700.00 | Window Closed / Lapsed |