EP0097059B1
Expired / Lapsed
EP
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Skin treatment compositions
Assignee: Unilever NV
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Filing: 1983-06-15
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Granted: 1989-10-25
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Expires: 2003-06-15
Abstract
No abstract record available.
Inventors
- 👤 Paul Anthony Bowser
- 👤 Albert Fröling
- 👤 Lammert Heslinga
- 👤 Udo Marius Theodoor Houtsmuller
- 👤 Diederik Hendrik Nugteren
- 👤 Hendrik Jacob Johannes Pabon
- 👤 Colin Prottey
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-03 04:49
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/37; A61K8/68; A61Q; A61Q17/00; C; C07; C07C; C07C59/00; C07C59/40; C07C59/42; C07H; C07H13/00; C07H13/02; C07H13/04; C07H13/06; Y; Y10; Y10S; Y10S424/00; Y10S424/05
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
274 words
A composition suitable for topical application to human skin, which comprises a suitable vehicle, a perfume and, as an active ingredient, from 0.001 to 5% by weight of one or more compounds having the structure: in which X is H-, C 1 to C 10 alkyl, or . where R is chosen from HO-, C 1 to C 4 alkoxy, polyhydroxylalkoxy, N - sphingosyl and N - (glycosyl- sphinogosyl), a is an integer of from 7 to 49, and b is an integer of from 10 to 98; and in which Y is H-; or a residue of an (n-6-cis, 9-cis) unsaturated fatty acid or a residue of a derivative thereof, either residue having the structure: where Z is -OH or an epoxy oxygen x is an integer of from 16 to 20, y is an integer of from 24 to 36, and z is 0, or an integer of from 1 to 4; any such derivative having at least one olefinic double bond and at least one group Z located between the n-6 and n-10 positions inclusive, provided that: when z is 0 then y is an integer of from 26 to 36 or when z is an integer of from 1 to 4 then y is an integer of from 24 to 35 and provided also that: when X is H-, or C 1 to C 10 alkyl, then Y is and z is an integer of from 1 to 4 and provided also that: when Y is -H and R is -OH, a is an integer of from 23 to 49 and b is an integer of from 42 to 98.
Claim 2
Dependent Claim
274 words
A composition suitable for topical application to human skin, which comprises a suitable vehicle, a perfume and, as an active ingredient, from 0.001 to 5% by weight of one or more compounds having the structure: in which X is H-, C 1 to C 10 alkyl, or . where R is chosen from HO-, C 1 to C 4 alkoxy, polyhydroxylalkoxy, N - sphingosyl and N - (glycosyl- sphinogosyl), a is an integer of from 7 to 49, and b is an integer of from 10 to 98; and in which Y is H-; or a residue of an (n-6-cis, 9-cis) unsaturated fatty acid or a residue of a derivative thereof, either residue having the structure: where Z is -OH or an epoxy oxygen x is an integer of from 16 to 20, y is an integer of from 24 to 36, and z is 0, or an integer of from 1 to 4; any such derivative having at least one olefinic double bond and at least one group Z located between the n-6 and n-10 positions inclusive, provided that: when z is 0 then y is an integer of from 26 to 36 or when z is an integer of from 1 to 4 then y is an integer of from 24 to 35 and provided also that: when X is H-, or C 1 to C 10 alkyl, then Y is and z is an integer of from 1 to 4 and provided also that: when Y is -H and R is -OH, a is an integer of from 23 to 49 and b is an integer of from 42 to 98.
Claim 3
Dependent Claim
25 words
A composition according to claim 1, in which the active ingredient is an w-hydroxy fatty acid or a carboxy-substituted w-hydroxy fatty acid having the structure:
Claim 4
Dependent Claim
69 words
A composition according to claim 1 or 2, in which the active ingredient is an ω-hydroxy unsaturated fatty acid, or a carboxy-substituted w-hydroxy unsaturated fatty acid having the structure: where d is O or an integer of from 1 to 46 e is 0 or an integer of from 1 to 46 d+e is an integer of from 4 to 46 and f is the integer 1 or 2.
Claim 5
Dependent Claim
52 words
A composition according to any of claims 1, 2 or 3, in which the active ingredient is a mono-unsaturated w-hydroxy fatty acid or a carboxy-substituted mono-unsaturated w-hydroxy fatty acid having the structure: where p is an integer of from 21 to 23, and q is an integer of from 6 to 8.
Claim 6
Dependent Claim
19 words
A composition according to claim 4, in which the active ingredient is chosen from the w-hydroxy unsaturated fatty acids:
Claim 7
Dependent Claim
34 words
A composition according to claim 4, in which the active ingredient is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid wherein the substituent R is chosen from methoxy (14), ethoxy (15), propoxy (16) and butoxy (17).
Claim 8
Dependent Claim
36 words
A composition according to claim 4, in which the active ingredient is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid wherein the substituent R is chosen from mono-, di- and tri-substituted glycerols or acyl glycerols (18 to 22).
Claim 9
Dependent Claim
35 words
A composition according to claim 4, in which the active ingredient is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid wherein the substituent R is chosen from mono- and di- substituted glycols or acyl glycols (23, 24).
Claim 10
Dependent Claim
32 words
A composition according to claim 4, in which the active ingredient is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid wherein the substituent R is chosen from substituted inositol (25) or substituted glucose (26).
Claim 11
Dependent Claim
30 words
A composition according to claim 4, in which the active ingredient is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid wherein the substituent R is chosen from N-sphingosyl or N - (glycosylsphingosyl).
Claim 12
Dependent Claim
44 words
A composition according to claim 1, in which the active ingredient is chosen from hydroxy- or epoxy-derivatives of essential fatty acids having the structure: where z is an integer of from 1 to 4 or carboxy-substituted C 1 to C 10 alkyl derivatives thereof.
Claim 13
Dependent Claim
15 words
A composition according to claim 11, in which the hydroxy- or epoxy-derivatives are chosen from:
Claim 14
Dependent Claim
18 words
A composition according to claim 1, in which the active ingredient is chosen from esters having the structure:
Claim 15
Dependent Claim
49 words
A composition according to claim 13, in which the all cis n-6,9 fatty acid residue expressed as: where x is an integer of from 16 to 20 y is an integer of from 26 to 36, and z is O is derived from an essential fatty acid chosen from:
Claim 16
Dependent Claim
50 words
A composition according to claim 13, in which the ester is an w-(O-linoleoyl) fatty acid, or a carboxy-substituted derivative thereof, comprising from 30 to 34 carbon atoms, having the structure: where p is an integer of from 21 to 23 and q is an integer of from 6 to 8.
Claim 17
Dependent Claim
13 words
A composition according to claim 15, in which the ester is chosen from:
Claim 18
Dependent Claim
19 words
A composition according to any preceding claim in which the active ingredient forms from 0.01 to 0.1% by weight.
Claim 19
Dependent Claim
18 words
A composition according to any preceding claim in which the vehicle forms from 50 to 99.5% by weight.
Claim 20
Dependent Claim
18 words
A composition according to any preceding claim in which the perfume forms from 0.01 to 10% by weight.
Claim 21
Dependent Claim
27 words
A composition according to any preceding claim which further comprises an antoxidation inhibitor in an amount of from 0.005 to 5% by weight of the active ingredient.
Claim 22
Dependent Claim
161 words
A synthetic or purified fatty acid or fatty acid ester compound having a purity of at least 10% by weight and having the structure: where X is an unsaturated w-hydroxy fatty acid residue expressed as: where a' is an integer of from 27 to 33 b' is an integer of from 50 to 64, and R is chosen from HO-, C 1 to C 4 alkoxy, polyhydroxyalkoxy, N-sphingosyl, and N - (glycosylsphingosyl); and where Y is -H, or a residue of an (n-6-cis, 9-cis) unsaturated fatty acid or a residue of a derivative thereof, either residue having the structure: where Z is -OH or an epoxy oxygen x is an integer of from 16 to 20 y is an integer of from 24 to 36, and z is 0 or an integer of from 1 to 4, any such derivative having at least one olefinic double bond and at least one group Z located between the n-6 and n-10 positions inclusive.
Claim 23
Dependent Claim
161 words
A synthetic or purified fatty acid or fatty acid ester compound having a purity of at least 10% by weight and having the structure: where X is an unsaturated w-hydroxy fatty acid residue expressed as: where a' is an integer of from 27 to 33 b' is an integer of from 50 to 64, and R is chosen from HO-, C 1 to C 4 alkoxy, polyhydroxyalkoxy, N-sphingosyl, and N - (glycosylsphingosyl); and where Y is -H, or a residue of an (n-6-cis, 9-cis) unsaturated fatty acid or a residue of a derivative thereof, either residue having the structure: where Z is -OH or an epoxy oxygen x is an integer of from 16 to 20 y is an integer of from 24 to 36, and z is 0 or an integer of from 1 to 4, any such derivative having at least one olefinic double bond and at least one group Z located between the n-6 and n-10 positions inclusive.
Claim 24
Dependent Claim
55 words
A compound according to claim 21, which is an unsaturated fatty acid having the structure: where d' is O or an integer of from 1 to 30 e' is 0 or an integer of from 1 to 30 d'+e' is an integer of from 24 to 30, and f is the integer 1 or 2.
Claim 25
Dependent Claim
19 words
A compound according to claim 21 or 22, which is a mono-unsaturated w-hydroxy fatty acid having the structure: where
Claim 26
Dependent Claim
57 words
A compound according to claim 21, which is a carboxy-substituted w-hydroxy unsaturated fatty acid having the structure: where d is 0 or an integer of from 1 to 30 e is O or an integer of from 1 to 30 d+e is an integer of from 24 to 30, and f is the integer 1 or 2.
Claim 27
Dependent Claim
30 words
A compound according to claim 29, which is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid, wherein the substituent R is chosen from methoxy (14), ethoxy (15), propoxy (16) and butoxy (17).
Claim 28
Dependent Claim
32 words
A compound according to claim 29, which is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid, wherein the substituent R is chosen from mono-, di- and tri-substituted glycerols or acyl glycerols (18 to 22).
Claim 29
Dependent Claim
28 words
A compound according to claim 29, which is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid, wherein the substituent R is chosen from mono- and di-substituted glycols or acyl glycols.
Claim 30
Dependent Claim
28 words
A compound according to claim 29, which is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid, wherein the substituent R is chosen from substituted inositol (25) or substituted glucose (26).
Claim 31
Dependent Claim
28 words
A compound according to claim 29, which is a carboxy-substituted mono-unsaturated w-hydroxy fatty acid, wherein the substituent R is chosen from N - sphingosyl or N - (glycosylsphingosyl).
Claim 32
Dependent Claim
13 words
A compound according to claim 21, which is an ester having the structure:
Claim 33
Dependent Claim
23 words
Compounds as claimed in any of claims 21 to 53 for use in the topical treatment of pathologically dry, damaged or diseased skin.
References Cited (Backward Citations)
No citation records indexed.
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