Patent US5193545A successfully refreshed from Google Patents.
US5193545A
Expired / Lapsed
US
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Device for determining at least one medical variable
Assignee: AVL Medical Instruments AG
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Filing: 1990-02-07
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Granted: 1993-03-16
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Expires: 2010-02-07
Abstract
Abstract A device designed for determining one or more medical variables in living organisms, comprises a part to be inserted into the tissue of the organism, which has an exchange channel with openings into the tissue. The device comprising a delivery unit connected with the exchange channel for the delivery of a perfusion fluid and its drainage after partial equilibration with the medical variable or quantity to be measured, i.e., preferably glucose concentration, and comparatively constant endogenous or exogenous marker variables. The device further comprising an analyzing unit for measuring the medical variable and one marker variable, and an evaluation unit for determining the actual concentration of the medical variable with the use of the marker variables. The proposal is put forward that the part to be inserted into the tissue is configured as a flexible plastic cannula, and that this cannula is provided with a puncturing needle on one end, and that the two ends of the cannula are connected to feeder and drainage tubes of the delivery unit both on the pressure and suction side.
Inventors
- 👤 Hermann Marsoner
- 👤 Falko Skrabal
- 👤 Helmut List
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:34
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/14542; A61B5/14525; A61B5/14528; A61B5/14532; A61B5/1468; A61B5/1473; A61B5/68; A61B5/6846; A61B5/6847; A61B5/686; Y; Y10; Y10S; Y10S128/00; Y10S128/13
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
133 words
A device for determining the concentration of at least one substance in organic tissue, comprising: a flexible plastic cannula, for insertion into said organic tissue, said cannula having an exchange channel with perforations, a feeder end having a feeder end connection and a drainage end having a drainage end connection; a delivery unit having a feeder tube comprising a connection which mates with the feeder end connection, said delivery unit providing a perfusion fluid which travels through said feeder end and into said exchange channel; an analyzing unit having a drainage tube which comprises a connection mating with said drainage end connection; and an evaluation unit connected to said delivery unit and said analyzing unit, said plastic cannula having a puncturing needle connected to one of said feeder end and said drainage end.
Claim 2
Independent Claim
133 words
A device for determining the concentration of at least one substance in organic tissue, comprising: a flexible plastic cannula, for insertion into said organic tissue, said cannula having an exchange channel with perforations, a feeder end having a feeder end connection and a drainage end having a drainage end connection; a delivery unit having a feeder tube comprising a connection which mates with the feeder end connection, said delivery unit providing a perfusion fluid which travels through said feeder end and into said exchange channel; an analyzing unit having a drainage tube which comprises a connection mating with said drainage end connection; and an evaluation unit connected to said delivery unit and said analyzing unit, said plastic cannula having a puncturing needle connected to one of said feeder end and said drainage end.
Claim 3
Dependent Claim
20 words
A device according to claim 1, wherein a smooth transition is provided from said puncturing needle to said plastic cannula.
Claim 4
Dependent Claim
37 words
A device according to claim 1, wherein said puncturing needle comprises said drainage end of said plastic cannula and said connection of said drainage tube, is provided with a pierceable septum for connection with said puncturing needle.
Claim 5
Dependent Claim
22 words
A device according to claim 1, wherein a mandrin is disposed within said exchange channel for mechanical cleaning of said exchange channel.
Claim 6
Independent Claim
208 words
A device for determining the concentration of at least one substance in organic tissue, comprising: a flexible cannula inserted into said organic tissue, said cannula having a feeder end, a drainage end, and an exchange channel, said exchange channel having perforations between said feeder and drainage ends, said perforations being in contact with said tissue; a delivery means having a feeder tube connected to the feeder end of the plastic cannula for feeding a perfusion fluid through said feeder end into said exchange channel and into contact with said tissue through said perforations; a collecting vessel for draining said perfusion fluid from said drainage end after partial equilibration with said substance to be determined, where the degree of equilibration is indicated by one of endogenous and exogenous marker variables; an analyzing means for measuring the concentration of said substance to be determined and at least one of said marker variables, said analyzing means having drainage tube means for connecting to said drainage end and for connecting to said collecting vessel; and an evaluation means connected to the delivery unit, the collecting vessel and the analyzing means, said evaluation means for determining an actual concentration of said substance to be determined using at least one of said marker variables.
Claim 7
Independent Claim
208 words
A device for determining the concentration of at least one substance in organic tissue, comprising: a flexible cannula inserted into said organic tissue, said cannula having a feeder end, a drainage end, and an exchange channel, said exchange channel having perforations between said feeder and drainage ends, said perforations being in contact with said tissue; a delivery means having a feeder tube connected to the feeder end of the plastic cannula for feeding a perfusion fluid through said feeder end into said exchange channel and into contact with said tissue through said perforations; a collecting vessel for draining said perfusion fluid from said drainage end after partial equilibration with said substance to be determined, where the degree of equilibration is indicated by one of endogenous and exogenous marker variables; an analyzing means for measuring the concentration of said substance to be determined and at least one of said marker variables, said analyzing means having drainage tube means for connecting to said drainage end and for connecting to said collecting vessel; and an evaluation means connected to the delivery unit, the collecting vessel and the analyzing means, said evaluation means for determining an actual concentration of said substance to be determined using at least one of said marker variables.
Claim 8
Dependent Claim
45 words
A device according to claim 5, wherein the feeder end of said plastic cannula has a Luer connection to be coupled to said feeder tube of said delivery unit, and wherein said drainage end of said plastic cannula is also provided with a Luer connection.
Claim 9
Dependent Claim
30 words
A device according to claim 5, wherein said substance to be determined is glucose and wherein at least one of the marker variables is a conductivity of said perfusion fluid.
Claim 10
Dependent Claim
99 words
A device according to claim 5, wherein said plastic cannula comprises a fixed stop at one of said feeder and drainage ends of said exchange channel, and a movable stop at the other of said feeder and drainage ends of said exchange channel, said movable stop being slipped over one of said feeder end and said drainage end of said plastic cannula after the same end has been threaded through said tissue, said perforations of said exchange channel being situated between said fixed and movable stops and held in contact with said tissue by said fixed and movable stops.
Claim 11
Dependent Claim
33 words
A device according to claim 5, wherein said exchange channel enters said tissue at one location and exits said tissue at a different location so that a loop is formed through said tissue.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-03-15 | 1996-09-14 | 1997-03-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-03-15 | 2000-09-14 | 2001-03-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-03-15 | 2004-09-14 | 2005-03-16 | $7700.00 | Window Closed / Lapsed |