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US5170805A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of destroying tissue such as a gall bladder utilizing a sclerosing agent alone or with a symphysis agent

Assignee: DSM Biomedical Inc
•
Filing: 1990-12-11
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Granted: 1992-12-15
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Expires: 2010-12-11
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Abstract

Abstract A method of destroying tissue such as a gall bladder located within the body of a living. A sclerosing agent is introduced into the body in a volume contiguous with the surface of the tissue to be destroyed. The sclerosing agent comprises a flowable material made up of a liquid carrier and a large plurality of abrasive particles, e.g., acicular particles of carborundum, silicon carbide, etc., Optionally, a symphysis agent, such as an antibiotic, may be introduced into the volume. Once the agent is introduced, it is caused to circulate therein whereupon its scrapes across the surface of the tissue to effect the sclerosing thereof.

Inventors

  • 👤 Kenneth Kensey
  • 👤 John Nash

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 12:15
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61B; A61B17/00; A61B17/32; A61B17/3205; A61B17/3207; A61B17/320758; A61K31/33; A61K31/395; A61K31/41; A61K31/425; A61K31/429; A61K31/43; A61K31/65; A61K31/695; A61K33/00; A61K33/06; A61K33/08; A61B17/22; A61B2017/22082; A61B2017/22084; A61B2017/320004; A61B2217/00; A61B2217/002; A61B2217/005; A61B2217/007

Claims Analysis

Total Claims: 42
Claim 1
Independent Claim 83 words
A method of destroying tissue located within the body of a living being, said tissue being located adjacent a volume into which a flowable material may be introduced, said tissue having a surface contiguous with said volume, said method comprising introducing a flowable material comprising a liquid carrier and a large plurality of abrasive particles into said volume, creating a circulating flow of said material within said volume whereupon said flowable material engages said surface of said tissue to effect the sclerosing thereof.
Claim 2
Independent Claim 83 words
A method of destroying tissue located within the body of a living being, said tissue being located adjacent a volume into which a flowable material may be introduced, said tissue having a surface contiguous with said volume, said method comprising introducing a flowable material comprising a liquid carrier and a large plurality of abrasive particles into said volume, creating a circulating flow of said material within said volume whereupon said flowable material engages said surface of said tissue to effect the sclerosing thereof.
Claim 3
Dependent Claim 19 words
The method of claim 1 wherein said liquid has a viscosity of at least 1 at 70 degrees Fahrenheit.
Claim 4
Dependent Claim 10 words
The method of claim 1 wherein said particles are acicular.
Claim 5
Dependent Claim 10 words
The method of claim 2 wherein said particles are acicular.
Claim 6
Dependent Claim 23 words
The method of claim 1 wherein said particles are of a size in the range of 5 microns to 1 mm in diameter.
Claim 7
Dependent Claim 23 words
The method of claim 2 wherein said particles are of a size in the range of 5 microns to 1 mm in diameter.
Claim 8
Dependent Claim 23 words
The method of claim 3 wherein said particles are of a size in the range of 5 microns to 1 mm in diameter.
Claim 9
Dependent Claim 23 words
The method of claim 5 wherein said particles are of a size in the range of 5 microns to 1 mm in diameter.
Claim 10
Dependent Claim 23 words
The method of claim 2 wherein said liquid has a viscosity in the range of 1 to 100 centipoise at 70 degrees Fahrenheit.
Claim 11
Dependent Claim 23 words
The method of claim 3 wherein said liquid has a viscosity in the range of 1 to 100 centipoise at 70 degrees Fahrenheit.
Claim 12
Dependent Claim 23 words
The method of claim 5 wherein said liquid has a viscosity in the range of 1 to 100 centipoise at 70 degrees Fahrenheit.
Claim 13
Dependent Claim 12 words
The method of claim 1 wherein said tissue is the gall bladder.
Claim 14
Dependent Claim 20 words
The method of claim 12 wherein said liquid has a viscosity of at least 1 centipoise at 70 degrees Fahrenheit.
Claim 15
Dependent Claim 10 words
The method of claim 12 wherein said particles are acicular.
Claim 16
Dependent Claim 10 words
The method of claim 13 wherein said particles are acicular.
Claim 17
Dependent Claim 20 words
The method of claim 1 wherein the liquid is selected from the group of ethanol, saline or a contrast media.
Claim 18
Dependent Claim 20 words
The method of claim 2 wherein the liquid is selected from the group of ethanol, saline or a contrast media.
Claim 19
Dependent Claim 20 words
The method of claim 3 wherein the liquid is selected from the group of ethanol, saline or a contrast media.
Claim 20
Dependent Claim 22 words
The method of claim 1 wherein the abrasive particles are chosen from the group of carborundum, silicon carbide, aluminum oxide and silica.
Claim 21
Dependent Claim 22 words
The method of claim 2 wherein the abrasive particles are chosen from the group of carborundum, silicon carbide, aluminum oxide and silica.
Claim 22
Dependent Claim 22 words
The method of claim 3 wherein the abrasive particles are chosen from the group of carborundum, silicon carbide, aluminum oxide and silica.
Claim 23
Dependent Claim 31 words
The method of claim 1 additionally comprising the step of introducing a fusing liquid into said volume and permitting said fusing liquid to remain therein for a predetermined period of time.
Claim 24
Dependent Claim 32 words
The method of claim 12 additionally comprising the step of introducing a fusing liquid into said gall bladder and permitting said fusing liquid to remain therein for a predetermined period of time.
Claim 25
Dependent Claim 12 words
The method of claim 22 wherein the fusing liquid comprises an antibiotic.
Claim 26
Dependent Claim 12 words
The method of claim 23 wherein the fusing liquid comprises an antibiotic.
Claim 27
Dependent Claim 19 words
The method of claim 24 wherein the antibiotic is chosen from the group of bleomycin, ampicillin, rolitetracycline and tetracycline.
Claim 28
Dependent Claim 16 words
The method of claim 26 wherein the rolitetracycline is introduced in combination with sodium tetradecyl sulfate.
Claim 29
Dependent Claim 23 words
The method of claim 11 wherein the concentration of rolitetracycline is approximately 3.5% and the concentration of sodium tetradecyl sulfate is approximately 3%.
Claim 30
Dependent Claim 19 words
The method of claim 25 wherein the antibiotic is chosen from the group of bleomycin, ampicillin, rolitetracycline and tetracycline.
Claim 31
Dependent Claim 16 words
The method of claim 29 wherein the rolitetracycline is introduced in combination with sodium tetradecyl sulfate.
Claim 32
Dependent Claim 23 words
The method of claim 30 wherein the concentration of rolitetracycline is approximately 3.5% and the concentration of sodium tetradecyl sulfate is approximately 3%.
Claim 33
Dependent Claim 12 words
The method of claim 22 wherein the fusing liquid comprises nitrogen mustard.
Claim 34
Dependent Claim 11 words
The method of claim 23 wherein the fusing liquid comprises quinacrine.
Claim 35
Dependent Claim 13 words
The method of claim 1 wherein the circulating flow is a vortex flow.
Claim 36
Dependent Claim 13 words
The method of claim 12 wherein the circulating flow is a vortex flow.
Claim 37
Dependent Claim 39 words
The method of claim 34 additionally comprising providing a device to be introduced into said volume, wherein the vortex flow is created by the device introduced into said volume and wherein said flowable material is introduced by said device.
Claim 38
Dependent Claim 39 words
The method of claim 35 additionally comprising providing a device to be introduced into said volume, wherein the vortex flow is created by the device introduced into said volume and wherein said flowable material is introduced by said device.
Claim 39
Dependent Claim 11 words
The method of claim 36 wherein the device is a catheter.
Claim 40
Dependent Claim 11 words
The method of claim 37 wherein the device is a catheter.
Claim 41
Dependent Claim 12 words
The method of claim 38 wherein the catheter has a working head.
Claim 42
Dependent Claim 12 words
The method of claim 39 wherein the catheter has a working head.

References Cited (Backward Citations)

US3316910A Cited
US3942519A Cited
US4601698A Cited
US4902276A Cited
US4857046A Cited
US5018508A Cited
US5037431A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-12-15 1996-06-15 1996-12-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-12-15 2000-06-15 2000-12-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-12-15 2004-06-15 2004-12-15 $7700.00 Window Closed / Lapsed

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