US5152784A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Prosthetic devices coated with a polypeptide with type IV collagen activity
Assignee: University of Minnesota System
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Filing: 1991-05-22
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Granted: 1992-10-06
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Expires: 2011-05-22
Abstract
Abstract A polypeptide having the following formula is provided: gly-glu-phe-tyr-phe-asp-leu-arg-leu-lys-gly-asp-lys which can bind heparin and promote cellular adhesion. Medical devices such as prosthetic implants, percutaneous devices and cell culture substrates coated with a composition including the polypeptide are also provided.
Inventors
- 👤 Photini-Effie C. Tsilibary
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 13:12
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/78
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
22 words
A prosthetic device designed for placement in vivo, comprising a surface coated with a composition comprising a polypeptide of the formula: gly-glu-phe-tyr-phe-asp-leu-arg-leu-lys-gly-asp-lys.
Claim 2
Dependent Claim
22 words
A prosthetic device designed for placement in vivo, comprising a surface coated with a composition comprising a polypeptide of the formula: gly-glu-phe-tyr-phe-asp-leu-arg-leu-lys-gly-asp-lys.
Claim 3
Dependent Claim
16 words
The prosthetic device of claim 1, wherein said surface constitutes a portion of a vascular graft.
Claim 4
Dependent Claim
16 words
The prosthetic device of claim 1, wherein said surface is made of a synthetic resin fiber.
Claim 5
Dependent Claim
17 words
The prosthetic device of claim 1, wherein said surface constitutes a portion of an intraocular contact lens.
Claim 6
Dependent Claim
17 words
The prosthetic device of claim 1, wherein said surface constitutes a portion of a hip replacement implant.
Claim 7
Dependent Claim
16 words
The prosthetic device of claim 1, wherein said surface constitutes a portion of a percutaneous device.
Claim 8
Dependent Claim
23 words
A prosthetic device in accordance with claim 3, wherein said synthetic resin fiber is selected from the group consisting of nitrocellulose or polyester.
Claim 9
Dependent Claim
17 words
A prosthetic device in accordance with claim 3, wherein said synthetic resin fiber is a polyethylene terephthalate.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-10-06 | 1996-04-06 | 1996-10-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-10-06 | 2000-04-06 | 2000-10-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-10-06 | 2004-04-06 | 2004-10-06 | $7700.00 | Window Closed / Lapsed |