US5151655A
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Magnetic resonance imaging using a back-to-back pulse sequence
Assignee: Baylor Research Institute
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Filing: 1990-08-17
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Granted: 1992-09-29
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Expires: 2010-08-17
Abstract
Abstract Methods for improved MR imaging of an object by the use of back-to-back adiabatic RF pulse sequences. In one embodiment, a selective component suppressed MR image of the internal structure of an object is produced from a series of gradient echoes received in response to the generation of back-to-back opposing adiabatic half passage selective component suppressive RF pulses separated by 180 degrees in phase. In another embodiment, an enhanced MR image of the internal structure of an object is produced from a series of gradient echoes received in response to the generation of back-to-back opposing adiabatic half passage selective component suppressive RF pulses separated by 90 degrees in phase.
Inventors
- 👤 Steven E. Harms
- 👤 Duane P. Flamig
- 👤 Richard H. Griffey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 16:29
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/483; G01R33/4833; G01R33/54; G01R33/56; G01R33/561
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
126 words
For a three dimensional object comprised of at least two components and having an x-axis, a y-axis and a z-axis, a method of producing a selective component suppressed MR image of the internal structure of said object comprising the steps of: generating a uniform magnetic field to magnetize said object; generating a first, second, and third changing magnetic fields along said x-axis, y-axis, and z-axis, respectively; generating a series of back-to-back selective component suppressive RF pulses to produce transverse magnetization in said components of said object other than said component to be suppressed; receiving a series of gradient echoes in response to said generated series of back-to-back selective component suppressive RF pulses; and producing an image of said object in which said selected component is suppressed.
Claim 2
Dependent Claim
126 words
For a three dimensional object comprised of at least two components and having an x-axis, a y-axis and a z-axis, a method of producing a selective component suppressed MR image of the internal structure of said object comprising the steps of: generating a uniform magnetic field to magnetize said object; generating a first, second, and third changing magnetic fields along said x-axis, y-axis, and z-axis, respectively; generating a series of back-to-back selective component suppressive RF pulses to produce transverse magnetization in said components of said object other than said component to be suppressed; receiving a series of gradient echoes in response to said generated series of back-to-back selective component suppressive RF pulses; and producing an image of said object in which said selected component is suppressed.
Claim 3
Dependent Claim
83 words
A method of producing a selective component suppressed MR image according to claim 1 wherein the step of generating said series of back-to-back selective component suppressive RF pulses further comprises the steps of: generating a first selective component suppressive RF pulse, said first RF pulse having an amplitude and a phase; and immediately generating a second selective component suppressive RF pulse after completing the generation of said first RF pulse, said second RF pulse produced by shifting said phase by approximately 180 degrees.
Claim 4
Dependent Claim
37 words
A method of producing a selective component suppressed MR image according to claim 1 wherein said series of back-to-back selective component suppressive RF pulses generates a net tip angle of zero degrees in said component being suppressed.
Claim 5
Dependent Claim
40 words
A method of producing a selective component suppressed MR image according to claim 1 wherein said series of back-to-back selective component suppressive RF pulses are generated at a frequency range corresponding to the resonant frequency for said component being suppressed.
Claim 6
Dependent Claim
35 words
A method of producing a selective component suppressed MR image according to claim 1 wherein interference between RF and gradient echoes are minimized, thereby minimizing the production of artifacts during the production of said image.
Claim 7
Dependent Claim
30 words
A method of producing a selective component suppressed MR image according to claim 1 wherein the production of artifacts is prevented by jittering successive pairs of back-to-back opposing RF pulses.
Claim 8
Dependent Claim
38 words
A method of producing a selective component suppressed MR image according to claim 1 wherein successive pairs of back-to-back opposing RF pulses are shifted by a quantitized amount to maximize the signal intensity of the produced MR image.
Claim 9
Dependent Claim
36 words
A method of producing a selective component suppressed MR image according to claim 1 wherein said series of back-to-back selective component suppressive RF pulses is comprised of a series of back-to-back opposing adiabatic half passage pulses.
Claim 10
Dependent Claim
88 words
A method of producing a selective component suppressed MR image according to claim 8 wherein the step of generating said series of back-to-back opposing adiabatic half passage pulses further comprises the steps of: generating a first selective component suppressive adiabatic RF pulse, said first adiabatic RF pulse having an amplitude and a phase; and immediately generating a second selective component suppressive adiabatic RF pulse after completing the generation of said first adiabatic RF pulse, said second adiabatic RF pulse produced by shifting said phase by approximately 180 degrees.
Claim 11
Dependent Claim
30 words
A method of producing a selective component suppressed MR image according to claim 9 wherein each of said selective component suppressive adiabatic RF pulses are generated for approximately 200 microseconds.
Claim 12
Dependent Claim
20 words
A method of producing a selective component suppressed MR image according to claim 10 wherein said suppressed component is water.
Claim 13
Dependent Claim
20 words
A method of producing a selective component suppressed MR image according to claim 10 wherein said suppressed component is fat.
Claim 14
Dependent Claim
31 words
A method of producing a selective component suppressed MR image according to claim 12 wherein suppressing the fat component reduces the production of artifacts during the production of said MR image.
Claim 15
Dependent Claim
48 words
A method of producing a selective component suppressed MR image according to claim 12 and further comprising the step of providing an echo time T E between said generated back-to-back opposing adiabatic half passage pulses and said received gradient echoes on the order of 2.8 to 3.2 msec.
Claim 16
Dependent Claim
41 words
A method of producing a selective component suppressed MR image according to claim 14 and further comprising the step of providing a repetition time T R between the generation of successive back-to-back opposing adiabatic half passage pulses of approximately 20 msec.
Claim 17
Dependent Claim
31 words
A method of producing a selective component suppressed MR image according to claim 15 wherein said back-to-back opposing adiabatic half passage pulses are generated at a frequency of approximately 64 MHz.
Claim 18
Dependent Claim
28 words
A method of producing a selective component suppressed MR image according to claim 16 wherein an MR angiogram is produced from a ray tracing reformatting of the data.
Claim 19
Independent Claim
110 words
A method of producing an enhanced three dimensional magnetic resonance image of an object comprised of at least one component and having an x-axis, a y-axis and a z-axis, comprising the steps of: generating a uniform magnetic field to magnetize said object; generating a first, second, and third changing magnetic fields along said x-axis, y-axis, and z-axis, respectively; producing transverse magnetization in said object; maximizing uniform excitation of said at least one component of said object; receiving a series of gradient echoes in response to said maximized uniform excitation of said at least one component; and producing an enhanced image of said object from said series of received gradient echoes.
Claim 20
Independent Claim
110 words
A method of producing an enhanced three dimensional magnetic resonance image of an object comprised of at least one component and having an x-axis, a y-axis and a z-axis, comprising the steps of: generating a uniform magnetic field to magnetize said object; generating a first, second, and third changing magnetic fields along said x-axis, y-axis, and z-axis, respectively; producing transverse magnetization in said object; maximizing uniform excitation of said at least one component of said object; receiving a series of gradient echoes in response to said maximized uniform excitation of said at least one component; and producing an enhanced image of said object from said series of received gradient echoes.
Claim 21
Dependent Claim
63 words
A method of producing an enhanced three dimensional magnetic resonance image of an object according to claim 18 wherein the step of producing transverse magnetization in said object further comprises the step of generating a series of back-to-back RF pulses to produce transverse magnetization in said object, said series of back-to-back RF pulses maximizing said uniform excitation of said at least one component.
Claim 22
Dependent Claim
78 words
A method of producing an enhanced three dimensional magnetic resonance image of an object according to claim 19 wherein the step of generating said series of back-to-back RF pulses further comprises the steps of: generating a first RF pulse, said first RF pulse having an amplitude and a phase; and immediately generating a second RF pulse after completing the generation of said first RF pulse, said second RF pulse produced by shifting said phase by approximately 90 degrees.
Claim 23
Dependent Claim
34 words
A method of producing a selective component suppressed MR image according to claim 20 wherein the production of artifacts from steady state magnetization is prevented by jittering successive pairs of back-to-back opposing RF pulses.
Claim 24
Dependent Claim
38 words
A method of producing a selective component suppressed MR image according to claim 20 wherein successive pairs of back-to-back opposing RF pulses are shifted by a quantitized amount to maximize the signal intensity of the produced MR image.
Claim 25
Dependent Claim
35 words
A method of producing an enhanced three dimensional magnetic resonance image of an object according to claim 21 wherein said back-to-back RF pulses is comprised of a series of back-to-back opposing adiabatic half passage pulses.
Claim 26
Dependent Claim
31 words
A method of producing an enhanced three dimensional magnetic resonance image of an object according to claim 23 wherein each of said adiabatic RF pulses are generated for approximately 200 microseconds.
Claim 27
Dependent Claim
52 words
A method of producing an enhanced three dimensional magnetic resonance image of an object according to claim 24 and further comprising the step of providing an echo time T E between said generated back-to-back opposing adiabatic half passage pulses and said received gradient echoes on the order of 2.8 to 3.2 msec.
Claim 28
Dependent Claim
45 words
A method of producing an enhanced three dimensional magnetic resonance image of an object according to claim 25 and further comprising the step of providing a repetition time T R between the generation of successive back-to-back opposing adiabatic half passage pulses of approximately 20 msec.
Claim 29
Dependent Claim
35 words
A method of producing an enhanced three dimensional magnetic resonance image of an object according to claim 26 wherein said back-to-back opposing adiabatic half passage pulses are generated at a frequency of approximately 64 MHz.
References Cited (Backward Citations)
US4748409A
Cited
US4707658A
Cited
US4728890A
Cited
US4766379A
Cited
US4902974A
Cited
US4999580A
Cited
US4973906A
Cited
US4982161A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-09-29 | 1996-03-30 | 1996-09-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-09-29 | 2000-03-30 | 2000-09-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-09-29 | 2004-03-30 | 2004-09-29 | $7700.00 | Window Closed / Lapsed |