US4728890A
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US
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Motion artifact suppression technique of magnetic resonance imaging
Assignee: Philips Nuclear Medicine Inc
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Filing: 1986-06-27
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Granted: 1988-03-01
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Expires: 2006-06-27
Abstract
Abstract A pulse sequencer (40) controls a resonance excitation controls circuit (22), an inversion pulse controls circuit (24), a slice select gradient controls circuit (32), a read gradient controls circuit (34), and a phase encode gradient controls circuit (36) to cause an appropriate gradient pulse imaging sequence to be generated in the image region. The operator selects an appropriate imaging sequence such as a spin echo, inversion recovery, multi-echo, radient echo, or other conventional imaging sequence and the parameters, such as the number of repetitions, from an image pulse sequence and motion desensitization memory (44, 46). In the exemplary pulse sequences of FIGS. 2-4, this memory directs the formation of RF pulses (62, 66), slice selection pulses (60, 64) and read gradient pulse (70), phase encode gradient pulse (72), and the appropriate additional gradient pulses for rephasing signals from one or more of static, constant velocity, accelerating, and pulsatilitory tissue in the image region. By rephasing the magnetic resonance signal components from tissue moving with the selected motion characteristics such that the corresponding moments in time are set equal to zero, motion artifacts from moving tissue are suppressed.
Inventors
- 👤 Pradip M. Pattany
- 👤 James E. McNally
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:39
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/54; G01R33/56; G01R33/565; G01R33/56509; G01F; G01F1/00; G01F1/704; G01F1/708; G01F1/716; G01R33/4818; G01R33/482; G01R33/563; G01R33/56308; G01R33/56316
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
122 words
In a magnetic resonance image generating sequence, which includes at least the application of a radio frequency resonance excitation pulse, a slice select gradient pulse, and a read gradient pulse, the improvement comprising: in the direction of at least one of the slice select and read gradients, applying a plurality of motion desensitization gradient pulses between the resonance excitation pulse and the read gradient pulse, the amplitude and duration of each of the plurality of motion desensitization pulses being selected such that the sum of at least two of the zeroth, second, and third moments in time of the phase of the gradient pulses along the selected one of the slice select and read gradient directions are set equal to preselected values.
Claim 2
Dependent Claim
122 words
In a magnetic resonance image generating sequence, which includes at least the application of a radio frequency resonance excitation pulse, a slice select gradient pulse, and a read gradient pulse, the improvement comprising: in the direction of at least one of the slice select and read gradients, applying a plurality of motion desensitization gradient pulses between the resonance excitation pulse and the read gradient pulse, the amplitude and duration of each of the plurality of motion desensitization pulses being selected such that the sum of at least two of the zeroth, second, and third moments in time of the phase of the gradient pulses along the selected one of the slice select and read gradient directions are set equal to preselected values.
Claim 3
Dependent Claim
14 words
The method as set forth in claim 1 wherein the preselected value is zero.
Claim 4
Dependent Claim
21 words
The method as set forth in claim 1 wherein moments of order greater than three are also set equal to zero.
Claim 5
Dependent Claim
30 words
The method as set forth in claim 1 wherein the image generating sequence includes one of a spin echo, an inversion recovery, a multi-echo, and a gradient echo imaging sequence.
Claim 6
Dependent Claim
122 words
In a magnetic resonance image generating sequence, which includes at least the application of a radio frequency resonance excitation pulse, a slice select gradient pulse, and a read gradient pulse, the improvement comprising: applying at least four motion desensitization gradient pulses between the resonance excitation pulse and the read gradient pulse, the four motion desensitization gradient pulses being applied in a selected one of the read and slice select gradient directions, the amplitude and duration of the motion desensitization pulses being selected such that the sum of each of the zeroth, first, second, and third moments in time of the phase of the gradient pulses along the selected one of the slice select and read gradient directions is set equal to zero.
Claim 7
Dependent Claim
122 words
In a magnetic resonance image generating sequence, which includes at least the application of a radio frequency resonance excitation pulse, a slice select gradient pulse, and a read gradient pulse, the improvement comprising: applying at least four motion desensitization gradient pulses between the resonance excitation pulse and the read gradient pulse, the four motion desensitization gradient pulses being applied in a selected one of the read and slice select gradient directions, the amplitude and duration of the motion desensitization pulses being selected such that the sum of each of the zeroth, first, second, and third moments in time of the phase of the gradient pulses along the selected one of the slice select and read gradient directions is set equal to zero.
Claim 8
Dependent Claim
26 words
The method as set forth in claim 5 wherein the motion desensitization gradient pulses are applied in both the read and the slice select gradient directions.
Claim 9
Dependent Claim
233 words
In a magnetic resonance image generating sequence, which includes at least the application of a radio frequency resonance excitation pulse, a slice select gradient pulse, and a read gradient pulse, the improvement comprising: in the direction of at least one of the slice select and read gradients, applying at least one motion desensitization gradient pulse between the resonance excitation pulse and the read gradient pulse, the amplitude and duration of the motion desensitization pulse being selected such that the sum of at least one of the zeroth, first, second, and third moment in time of the phase of the gradient pulses along the selected one of the slice select and read gradient directions is set equal to a preselected value; determining the appropriate duration and amplitudes of the motion desensitization gradient pulses, the amplitude and duration determining steps including: selecting beginning and ending times for each gradient pulse, the number of motion desensitization gradient pulses being the same as the number of moments which are to be set to preselected values; along each of the slice select and read directions, setting the corresponding each term of the power series expansion: ##EQU9## to one of the preselected values and solving for the amplitudes of the motion desensitization gradients, γ is the gyromagnetic ratio, G(t) is the gradient at time t, and x o .sup.(j) is the jth differential of position x at time 0.
Claim 10
Dependent Claim
233 words
In a magnetic resonance image generating sequence, which includes at least the application of a radio frequency resonance excitation pulse, a slice select gradient pulse, and a read gradient pulse, the improvement comprising: in the direction of at least one of the slice select and read gradients, applying at least one motion desensitization gradient pulse between the resonance excitation pulse and the read gradient pulse, the amplitude and duration of the motion desensitization pulse being selected such that the sum of at least one of the zeroth, first, second, and third moment in time of the phase of the gradient pulses along the selected one of the slice select and read gradient directions is set equal to a preselected value; determining the appropriate duration and amplitudes of the motion desensitization gradient pulses, the amplitude and duration determining steps including: selecting beginning and ending times for each gradient pulse, the number of motion desensitization gradient pulses being the same as the number of moments which are to be set to preselected values; along each of the slice select and read directions, setting the corresponding each term of the power series expansion: ##EQU9## to one of the preselected values and solving for the amplitudes of the motion desensitization gradients, γ is the gyromagnetic ratio, G(t) is the gradient at time t, and x o .sup.(j) is the jth differential of position x at time 0.
Claim 11
Dependent Claim
25 words
The method as set forth in claim 7 wherein a matrix format is utilized to solve for the amplitudes of the motion desensitization gradient pulses.
Claim 12
Dependent Claim
174 words
In a magnetic resonance image generating sequence, which includes at least the application of a radio frequency resonance excitation pulse, a slice select gradient pulse, and a read gradient pulse, the improvement comprising: in the direction of at least one of the slice select and read gradients, applying at least one motion desensitization gradient pulse between the resonance excitation pulse and the read gradient pulse, each motion desensitization gradient pulse being generally trapezoidal in cross section having a rising leading portion, a central plateau portion, and a falling trailing end portion and wherein the rising portion and the falling portions are approximated by a series of rectangular pulses, the amplitude and duration of the motion desensitization pulses including the series of rising and falling portions approximately rectangular pulses being selected such that the sum of at least one of the zeroth, first, second, and third moments in time of the phase of the gradient pulses along the selected one of the slice select and read gradient directions is set equal to a preselected value.
Claim 13
Dependent Claim
174 words
In a magnetic resonance image generating sequence, which includes at least the application of a radio frequency resonance excitation pulse, a slice select gradient pulse, and a read gradient pulse, the improvement comprising: in the direction of at least one of the slice select and read gradients, applying at least one motion desensitization gradient pulse between the resonance excitation pulse and the read gradient pulse, each motion desensitization gradient pulse being generally trapezoidal in cross section having a rising leading portion, a central plateau portion, and a falling trailing end portion and wherein the rising portion and the falling portions are approximated by a series of rectangular pulses, the amplitude and duration of the motion desensitization pulses including the series of rising and falling portions approximately rectangular pulses being selected such that the sum of at least one of the zeroth, first, second, and third moments in time of the phase of the gradient pulses along the selected one of the slice select and read gradient directions is set equal to a preselected value.
Claim 14
Independent Claim
184 words
A method of generating magnetic resonance image representations, the method comprising: generating a generally uniform magnetic field through an image region in which a subject to be imaged is positioned; applying a plurality of pulse sequences to the image region, each pulse sequence including the concurrent application of a first slice select gradient in a slice select direction and a resonance excitation RF pulse, the concurrent application of a second slice select gradient pulse and an RF inversion pulse to invert the spin magnetization of resonating nuclei, application of a read gradient pulse in a read direction concurrently with a spin echo, and application of a phase encode gradient pulse prior to the read gradient; the pulse sequence further including the application of a plurality of motion desensitization gradient pulses having components in the slice select and read gradient directions, the motion desensitization pulses having a duration and amplitude such that the sum of at least one of the zeroth, first, second, and third moments in time of the phase along each of the slice select and read gradient directions is a preselected value.
Claim 15
Independent Claim
184 words
A method of generating magnetic resonance image representations, the method comprising: generating a generally uniform magnetic field through an image region in which a subject to be imaged is positioned; applying a plurality of pulse sequences to the image region, each pulse sequence including the concurrent application of a first slice select gradient in a slice select direction and a resonance excitation RF pulse, the concurrent application of a second slice select gradient pulse and an RF inversion pulse to invert the spin magnetization of resonating nuclei, application of a read gradient pulse in a read direction concurrently with a spin echo, and application of a phase encode gradient pulse prior to the read gradient; the pulse sequence further including the application of a plurality of motion desensitization gradient pulses having components in the slice select and read gradient directions, the motion desensitization pulses having a duration and amplitude such that the sum of at least one of the zeroth, first, second, and third moments in time of the phase along each of the slice select and read gradient directions is a preselected value.
Claim 16
Dependent Claim
31 words
The method as set forth in claim 10 wherein the sum of the zeroth moments in each of the slice select and read gradients are zero whereby static material is rephased.
Claim 17
Dependent Claim
44 words
The method as set forth in claim 10 wherein the sum of the first moments in each of the slice select and read gradient directions are zero such that magnetic resonance signals from portions of the subject moving at a constant velocity are rephased.
Claim 18
Dependent Claim
40 words
The method as set forth in claim 10 wherein the sum of the second moments along each of the slice select and read gradient directions are zero such that magnetic resonance signals from accelerating portions of the subject are rephased.
Claim 19
Dependent Claim
44 words
The method as set forth in claim 10 wherein the sum of the third moments along each of the slice select and read gradient directions are zero such that magnetic resonance signals from portions of the subject moving with a pulsatile motion are rephased.
Claim 20
Independent Claim
296 words
An apparatus for generating motion desensitized magnetic resonance images, the apparatus comprising: main magnetic field means for generating a generally uniform magnetic field through an image region; a radio frequency pulse means for selectively applying radio frequency pulses to the image region, at least some of the radio frequency pulses being configured for exciting magnetic resonance of selected dipoles in the image region; a slice selection gradient control means for selectively applying magnetic field gradient pulse in a slice select direction across the image region; read gradient control means for selectively applying magnetic field gradient pulses across the image region in a read direction; a phase encode gradient control means for selectively applying magnetic field gradients in a phase encode direction across the image region; an imaging pulse sequence and motion desensitization memory means for storing amplitude and relative timing information for each of a plurality of selectable imaging sequences including RF, slice select gradient, read gradient, and phase encode gradient pulses, and motion desensitization magnetic field gradient pulses to be applied in each of the slice select and read gradient directions; a pulse sequence format means operatively connected with the imaging pulse sequence and motion desensitization pulse memory means and with the radio frequency pulse means, the slice select gradient control means, the read gradient control means, the phase encode gradient control means for causing the radio frequency pulse control means, the slice select gradient control means, the read gradient control means, and the phase encode gradient control means to apply the selected sequence of imaging and motion desensitization pulses to the image region; a radio frequency receiving means for receiving radio frequency magnetic resonance signals from the image region; and, image reconstruction means for forming an image representation from the received magnetic resonance signals.
Claim 21
Independent Claim
296 words
An apparatus for generating motion desensitized magnetic resonance images, the apparatus comprising: main magnetic field means for generating a generally uniform magnetic field through an image region; a radio frequency pulse means for selectively applying radio frequency pulses to the image region, at least some of the radio frequency pulses being configured for exciting magnetic resonance of selected dipoles in the image region; a slice selection gradient control means for selectively applying magnetic field gradient pulse in a slice select direction across the image region; read gradient control means for selectively applying magnetic field gradient pulses across the image region in a read direction; a phase encode gradient control means for selectively applying magnetic field gradients in a phase encode direction across the image region; an imaging pulse sequence and motion desensitization memory means for storing amplitude and relative timing information for each of a plurality of selectable imaging sequences including RF, slice select gradient, read gradient, and phase encode gradient pulses, and motion desensitization magnetic field gradient pulses to be applied in each of the slice select and read gradient directions; a pulse sequence format means operatively connected with the imaging pulse sequence and motion desensitization pulse memory means and with the radio frequency pulse means, the slice select gradient control means, the read gradient control means, the phase encode gradient control means for causing the radio frequency pulse control means, the slice select gradient control means, the read gradient control means, and the phase encode gradient control means to apply the selected sequence of imaging and motion desensitization pulses to the image region; a radio frequency receiving means for receiving radio frequency magnetic resonance signals from the image region; and, image reconstruction means for forming an image representation from the received magnetic resonance signals.
Claim 22
Dependent Claim
85 words
The apparatus as set forth in claim 15 wherein the motion desensitization gradient pulse amplitude and timing information is selected such that the sum of at least the zeroth, first, second, and third moments in time of the phase along each of the slice select and read gradient directions are selectively setable to a preselected value; and, a motion desensitization control means operatively connected with the pulse sequence and motion desensitization pulse memory means for selecting which sums are set equal to the preselected value.
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USPTO Annuity & Maintenance Windows
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| 3.5 Years (Year 4) | 1991-03-01 | 1991-08-31 | 1992-03-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-03-01 | 1995-08-31 | 1996-03-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-03-01 | 1999-08-31 | 2000-03-01 | $7700.00 | Window Closed / Lapsed |