US5147648A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of improving the adhesiveness of gels to mucosae
Assignee: Individual
•
Filing: 1990-09-17
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Granted: 1992-09-15
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Expires: 2010-09-17
Abstract
Abstract For improving the adherence of gels to the mucous membranes, one applies separately to the same area of a mucous membrane two components capable of forming together a gel, for example a metallic salt and at least one polysaccharide. This gel is useful as carrier for medicaments.
Inventors
- 👤 Christian Bannert
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 16:25
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0048; A61K31/00; A61K31/70; A61K31/715; A61K47/00; A61K47/30; A61K47/36; A61K9/0053; A61K9/006; A61P; A61P27/00; A61P27/02
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
106 words
The method of treating xerostomia with a gel having an improved adhesiveness to the oral mucosa of a human patient, which comprises first applying to the oral mucosa of said patient an aqueous solution of a calcium salt which is capable of forming a gel with a polysaccharide, where the calcium salt solution has a concentration of 0.01 to 50 mMols of calcium per 100 ml, and subsequently applying to the thus treated oral mucosa of said patient an aqueous solution of a polysaccharide selected from the group consisting of sodium alginate and pectin, where said polysaccharide solution contains 0.01 to 12.5% by weight of polysaccharide.
Claim 2
Independent Claim
106 words
The method of treating xerostomia with a gel having an improved adhesiveness to the oral mucosa of a human patient, which comprises first applying to the oral mucosa of said patient an aqueous solution of a calcium salt which is capable of forming a gel with a polysaccharide, where the calcium salt solution has a concentration of 0.01 to 50 mMols of calcium per 100 ml, and subsequently applying to the thus treated oral mucosa of said patient an aqueous solution of a polysaccharide selected from the group consisting of sodium alginate and pectin, where said polysaccharide solution contains 0.01 to 12.5% by weight of polysaccharide.
Claim 3
Dependent Claim
17 words
The method of claim 1, wherein said calcium salt is calcium chloride and said polysaccharide is pectin.
Claim 4
Dependent Claim
18 words
The method of claim 1, wherein said calcium salt is calcium gluconate and said polysaccharide is sodium alginate.
Claim 5
Dependent Claim
27 words
The method of claim 1, wherein the calcium salt solution and the polysaccharide solution are sequentially applied to the mucosa of the mouth by spraying or rinsing.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-09-15 | 1996-03-16 | 1996-09-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-09-15 | 2000-03-16 | 2000-09-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-09-15 | 2004-03-16 | 2004-09-15 | $7700.00 | Window Closed / Lapsed |