Pyrimidinyl tetrahydrofurans

Claim 1

A compound having the formula ##STR81## or a pharmaceutically acceptable salt thereof wherein R 1 is ##STR82## X 6 is fluoro, chloro, bromo, iodo, hydrogen, methyl, trilluoromethyl, ethyl, n-propyl, 2-fluoroethyl, 2-chloroethyl, or ##STR83## X 7 is hydrogen, alkyl, substituted alkyl, phenyl or substituted phenyl, X 9 is chloro, bromo, iodo, hydrogen, methyl, or trifluoromethyl, R 2 and R 3 are independently hydrogen, --PO 3 H 2 , or ##STR84## the term "alkyl" refers to straight and branched chained groups of 1 to 10 carbons, the term "substituted alkyl" refers to alkyl groups having one or more substituents selected from the group consisting of halogen, amino, azido, hydroxy, cyano, trialkylammonium (wherein each alkyl group has 1 to 6 carbons), alkoxy of 1 to 6 carbons, phenyl, substituted phenyl, and carboxy, and the term "substituted phenyl" refers to a phenyl substituted with one, two, or three groups selected from the group consisting of alkyl of 1 to 6 carbons, alkoxy of 1 to 6 carbons, halogen, trifluoromethyl, amino, alkylamino of 1 to 6 carbons, dialkylamino (wherein each alkyl group has 1 to 6 carbons), nitro, cyano, alkanoyloxy of 2 to 11 carbons, carboxy, carbonyl, and hydroxy.