Patent US5137902A successfully refreshed from Google Patents.
US5137902A
Expired / Lapsed
US
⏱️ 0.0 years remaining
4-alkylimidazole derivatives and anti-hypertensive use thereof
Assignee: EIDP Inc
•
Filing: 1991-02-04
•
Granted: 1992-08-11
•
Expires: 2011-02-04
Abstract
Abstract Angiotensin II antagonist antihypertensive compounds such as ##STR1## where R 2 is --CHO or --COOH and R 1 is ethyl have outstanding orally potency.
Inventors
- 👤 David J. Carini
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 03:24
CPC Classifications
C; C07; C07D; C07D403/00; C07D403/02; C07D403/10; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/415; A61P; A61P9/00; A61P9/12
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
39 words
An antihypertensive compound of the formula: ##STR7## where R 2 is --CHO or --COOH; when R 2 is --CHO, R 1 is methyl, ethyl, i-propyl, or t-butyl; and when R 2 is --COOH, R 1 is ethyl, or i-propyl.
Claim 2
Dependent Claim
39 words
An antihypertensive compound of the formula: ##STR7## where R 2 is --CHO or --COOH; when R 2 is --CHO, R 1 is methyl, ethyl, i-propyl, or t-butyl; and when R 2 is --COOH, R 1 is ethyl, or i-propyl.
Claim 3
Dependent Claim
15 words
The compound of claim 1 wherein R 2 is --CHO and R 1 is ethyl.
Claim 4
Dependent Claim
15 words
The compound of claim 1 wherein R 2 is --CHO and R 1 is t-butyl.
Claim 5
Dependent Claim
15 words
The compound of claim 1 wherein R 2 is --COOH and R 1 is ethyl.
Claim 6
Dependent Claim
30 words
A method of treating hypertension in a warm-blooded animal comprising orally administering to the animal a compound of claim 1 in an amount effective to lower the animal's blood pressure.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-08-11 | 1996-02-10 | 1996-08-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-08-11 | 2000-02-10 | 2000-08-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-08-11 | 2004-02-10 | 2004-08-11 | $7700.00 | Window Closed / Lapsed |