Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
272 words
A transdermal applicator for delivering at least one drug through the skin to the blood circulation system of a patient over an extended period of time comprising: a drug reservoir for containing at least one drug and having means for attachment to the skin of a patient and making an electrical connection therewith at an interface between the reservoir and the skin of the patient, means connected to said reservoir including a source of variable electrical potential for effecting delivery of said drug transdermally into the blood of the patient when the applicator is in use, said source having one electrical terminal electrically connected to said reservoir spaced from said interface and a second terminal positionable on the surface of the skin of the patient spaced from said interface and in circuit with said interface when said applicator is in use, means in said source of variable electrical potential for cyclically generating a complex composite pulse signal applied to said one terminal, said reservoir and through said interface when said second terminal is in electrical contact with the skin of the patient, said complex composite pulse signal comprising a conditioning negative directcurrent leading pulse followed by a sequence of pulses direct current pulses of different waveforms, amplitudes, frequencies and repetition rates, and timing means for applying the complex composite pulse signal as a composite total waveform signal with selected sequencies of different time intervals of waveform components effective to develop and maintain current flow including current flow within blood capillaries of the patient in the same direction of current flow as the leading direct current pulse of the complex composite pulse signal.
Claim 2
Dependent Claim
272 words
A transdermal applicator for delivering at least one drug through the skin to the blood circulation system of a patient over an extended period of time comprising: a drug reservoir for containing at least one drug and having means for attachment to the skin of a patient and making an electrical connection therewith at an interface between the reservoir and the skin of the patient, means connected to said reservoir including a source of variable electrical potential for effecting delivery of said drug transdermally into the blood of the patient when the applicator is in use, said source having one electrical terminal electrically connected to said reservoir spaced from said interface and a second terminal positionable on the surface of the skin of the patient spaced from said interface and in circuit with said interface when said applicator is in use, means in said source of variable electrical potential for cyclically generating a complex composite pulse signal applied to said one terminal, said reservoir and through said interface when said second terminal is in electrical contact with the skin of the patient, said complex composite pulse signal comprising a conditioning negative directcurrent leading pulse followed by a sequence of pulses direct current pulses of different waveforms, amplitudes, frequencies and repetition rates, and timing means for applying the complex composite pulse signal as a composite total waveform signal with selected sequencies of different time intervals of waveform components effective to develop and maintain current flow including current flow within blood capillaries of the patient in the same direction of current flow as the leading direct current pulse of the complex composite pulse signal.
Claim 3
Dependent Claim
54 words
A transdermal applicator for delivering at least one drug through the skin to the blood circulation system of a patient over an extended period of time according to claim 1, in which said timing means comprises spectral timing means comprising a timer and a microprocessor for selectively varying the time intervals of said sequence.
Claim 4
Dependent Claim
47 words
A transdermal applicator for delivering at least one drug through the skin to the blood circulation system of a patient over an extended period of time according to claim 1, in which said source of variable electrical potential comprises means for alternating the polarity of the source.
Claim 5
Dependent Claim
42 words
A transdermal applicator for delivering at least one drug through the skin to the blood circulation system of a patient over an extended period according to claim 1, including means for creating a short-circuit between said one terminal and said second terminal.
Claim 6
Dependent Claim
42 words
A transdermal applicator for delivering at least one drug through the skin to the blood circulation system of a patient over an extended period according to claim 1, including means for selectively interrupting pulse components of said complex signal in said sequences.