Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
318 words
A compound selected from imidazo[1,2-c]quinazolines of the formula I: ##STR25## in which: Y represents oxygen or sulfur; R 1 represents: a) alkyl having 1 to 6 carbon atoms, optionally substituted by phenyl optionally mono- or disubstituted by halogen or alkyl or alkoxy having 1 to 6 carbon atoms; b) mono-, bi- or tricyclic cycloalkyl having 3 to 10 carbon atoms; c) an aromatic group chosen from among: phenyl and phenyl mono- or disubstituted by halogen or alkyl or alkoxy having 1 to 6 carbon atoms, and furyl and thienyl, or d) alkoxycarbonyl, aminocarbonyl or N,N-dialkylaminocarbonyl, in which alkyl has 1 to 6 carbon atoms, or benzoyl optionally mono- or disubstituted by halogen atom or alkyl or alkoxy having 1 to 6 carbon atoms; R 2 represents hydrogen or halogen or alkyl having 1 to 6 carbon atoms optionally substituted by amino, alkylamino or dialkylamino in which alkyl has 1 to 6 carbon atoms; R 3 represents: a) hydrogen, b) alkyl radical having 1 to 6 carbon atoms, optionally substituted by phenyl optionally mono- or polysubstituted by alkyl or alkoxy having 1 to 6 carbon atoms, or c) a radical of formula: R--CO--A-- in which: A is alkylene having 1 to 6 carbon atoms, and R is alkoxy having 1 to 6 carbon atoms or an amino radical of formula: ##STR26## in which R' and R", identical or different, each represent hydrogen or alkyl having 1 to 6 carbon atoms optionally substituted by hydroxyl or alkoxy having 1 to 6 carbon atoms, or R' and R" form, together with the nitrogen atom to which they are attached, a saturated 5 or 6 membered heterocyclic radical optionally containing a second hetero atom selected from oxygen and nitrogen, remaining ring atoms being carbon, d) phenyl, optionally substituted by one or more alkyl or alkoxy having 1 to 6 carbon atoms; X represents hydrogen or halogen, and pharmacologically-acceptable acid addition salts thereof.
Claim 2
Dependent Claim
318 words
A compound selected from imidazo[1,2-c]quinazolines of the formula I: ##STR25## in which: Y represents oxygen or sulfur; R 1 represents: a) alkyl having 1 to 6 carbon atoms, optionally substituted by phenyl optionally mono- or disubstituted by halogen or alkyl or alkoxy having 1 to 6 carbon atoms; b) mono-, bi- or tricyclic cycloalkyl having 3 to 10 carbon atoms; c) an aromatic group chosen from among: phenyl and phenyl mono- or disubstituted by halogen or alkyl or alkoxy having 1 to 6 carbon atoms, and furyl and thienyl, or d) alkoxycarbonyl, aminocarbonyl or N,N-dialkylaminocarbonyl, in which alkyl has 1 to 6 carbon atoms, or benzoyl optionally mono- or disubstituted by halogen atom or alkyl or alkoxy having 1 to 6 carbon atoms; R 2 represents hydrogen or halogen or alkyl having 1 to 6 carbon atoms optionally substituted by amino, alkylamino or dialkylamino in which alkyl has 1 to 6 carbon atoms; R 3 represents: a) hydrogen, b) alkyl radical having 1 to 6 carbon atoms, optionally substituted by phenyl optionally mono- or polysubstituted by alkyl or alkoxy having 1 to 6 carbon atoms, or c) a radical of formula: R--CO--A-- in which: A is alkylene having 1 to 6 carbon atoms, and R is alkoxy having 1 to 6 carbon atoms or an amino radical of formula: ##STR26## in which R' and R", identical or different, each represent hydrogen or alkyl having 1 to 6 carbon atoms optionally substituted by hydroxyl or alkoxy having 1 to 6 carbon atoms, or R' and R" form, together with the nitrogen atom to which they are attached, a saturated 5 or 6 membered heterocyclic radical optionally containing a second hetero atom selected from oxygen and nitrogen, remaining ring atoms being carbon, d) phenyl, optionally substituted by one or more alkyl or alkoxy having 1 to 6 carbon atoms; X represents hydrogen or halogen, and pharmacologically-acceptable acid addition salts thereof.
Claim 3
Dependent Claim
14 words
A physiologically tolerated salt of a compound of claim 1 with a pharmacologically-acceptable acid.
Claim 4
Dependent Claim
7 words
Compound of claim 1 being 2-Ethoxycarbonyl-6-benzyl-5-oxo-5,6-dihydroimidazo[ 1,2-c]quinazoline.
Claim 5
Dependent Claim
6 words
Compound of claim 1 being 2-Phenyl-6-N,N-diethylaminocarbonylmethyl-5-oxo-5,6-dihydroimidazo[1,2-c]quinazoline.
Claim 6
Dependent Claim
6 words
Compound of claim 1 being 2-(p-Methoxyphenyl)-6-N,N-diethylaminocarbonylmethyl-5-oxo-5,6-dihydroimidazo[1,2-c]quinazoline.
Claim 7
Dependent Claim
6 words
Compound of claim 1 being 2-Phenyl-6-(N-methyl-N-phenylacetamido)-5-oxo-5,6-dihydroimidazo[1,2-c]quinazoline.
Claim 8
Dependent Claim
6 words
Compound of claim 1 being 2-Phenyl-6-N,N-dipropylaminocarbonylmethyl-5-oxo-5,6-dihydroimidazo[1,2-c]quinazoline.
Claim 9
Dependent Claim
6 words
Compound of claim 1 being 2-(m-Chlorophenyl)-3-methyl-6-N,N-dipropylaminocarbonylmethyl-5-oxo-5,6-dihydroimidazo[1,2-c]quinazoline.
Claim 10
Dependent Claim
25 words
A pharmaceutical composition useful for treating coronary smooth-muscle dysfunction containing as active principle a compound as claimed in claim 1 together with a pharmaceutically-acceptable carrier.
Claim 11
Dependent Claim
41 words
A method for treating a living animal afflicted with a coronary smooth muscle dysfunction, comprising the step of administering to the said living animal an amount of a compound of claim 1 which is effective for alleviation of the said conditions.