Patent US2812552A successfully refreshed from Google Patents.
Patent US5128145A successfully refreshed from Google Patents.
US5128145A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dosage form for Parkinson's disease, spasticity and muscle spasms
Assignee: Alza Corp
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Filing: 1991-08-02
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Granted: 1992-07-07
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Expires: 2011-08-02
Abstract
Abstract A dosage form is disclosed comprising a drug and a maltodextrin polymer for administering to a patient a drug in need of therapy.
Inventors
- 👤 David E. Edgren
- 👤 Gurdish K. Bhatti
- 👤 Howard A. Carpenter
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 23:51
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0004
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
156 words
A dosage form for delivering a drug to a drug receptor, wherein the dosage form comprises: (a) a wall comprising at least in part a composition permeable to the passage of fluid, which wall surrounds: (b) a compartment; (c) at least one exit port in the wall that connects the exterior of the dosage form with the compartment; (d) a dispensing composition in the compartment comprising a maltodextrin comprising a 500 to 1,000,000 molecular weight and a degree of polymerization of 3 to 6,140; (e) 1 mg to 750 mg of drug in the dispensing composition for delivering the drug, by the combined operations of (a) and (b), through the exit port from the dosage form; and, (f) a push composition in the compartment comprising a hydrogel and an osmotically effective solute, which composition in the presence of fluid that enters the compartment increases in volume and thereby pushes the dispensing composition from the dosage form.
Claim 2
Dependent Claim
156 words
A dosage form for delivering a drug to a drug receptor, wherein the dosage form comprises: (a) a wall comprising at least in part a composition permeable to the passage of fluid, which wall surrounds: (b) a compartment; (c) at least one exit port in the wall that connects the exterior of the dosage form with the compartment; (d) a dispensing composition in the compartment comprising a maltodextrin comprising a 500 to 1,000,000 molecular weight and a degree of polymerization of 3 to 6,140; (e) 1 mg to 750 mg of drug in the dispensing composition for delivering the drug, by the combined operations of (a) and (b), through the exit port from the dosage form; and, (f) a push composition in the compartment comprising a hydrogel and an osmotically effective solute, which composition in the presence of fluid that enters the compartment increases in volume and thereby pushes the dispensing composition from the dosage form.
Claim 3
Dependent Claim
53 words
The dosage form for delivering the drug to a drug receptor according to claim 1, wherein the dosage form comprises a drug selected from the group consisting of a gastric acid secretion inhibitor, a histamine receptor antagonist, an antiparkinson, an appetite suppressant, a contraceptive, a dopamine receptor agonist, and a smoking cessation aid.
Claim 4
Dependent Claim
40 words
The dosage form for delivering the drug to a drug receptor according to claim 1, wherein the exit port comprises a member selected from the group consisting of a pore, a porous overlay, a porous insert, and a microporous member.
Claim 5
Dependent Claim
150 words
An improvement in an osmotic dosage form for delivering a drug to a patient, wherein the osmotic dosage form comprises: (a) a wall comprising a composition permeable to the passage of fluid, which wall surrounds: (b) a compartment; (c) at least one passageway in the wall that connects the exterior of the osmotic dosage form with the compartment; (d) a composition in the compartment that increases its volume in the presence of fluid that enters the compartment; (e) a dose of a drug in the compartment; (f) a dose of a drug in contact with the exterior of the osmotic dosage form; and wherein the improvement comprises: (g) a maltodextrin in the compartment comprising a 500 to 1,000,000 molecular weight and a degree of polymerization of 3 to 6,140, which maltodextrin is compatible with the drug and aids in delivering the drug through the passageway from the osmotic dosage form.
Claim 6
Dependent Claim
150 words
An improvement in an osmotic dosage form for delivering a drug to a patient, wherein the osmotic dosage form comprises: (a) a wall comprising a composition permeable to the passage of fluid, which wall surrounds: (b) a compartment; (c) at least one passageway in the wall that connects the exterior of the osmotic dosage form with the compartment; (d) a composition in the compartment that increases its volume in the presence of fluid that enters the compartment; (e) a dose of a drug in the compartment; (f) a dose of a drug in contact with the exterior of the osmotic dosage form; and wherein the improvement comprises: (g) a maltodextrin in the compartment comprising a 500 to 1,000,000 molecular weight and a degree of polymerization of 3 to 6,140, which maltodextrin is compatible with the drug and aids in delivering the drug through the passageway from the osmotic dosage form.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-07-07 | 1996-01-06 | 1996-07-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-07-07 | 2000-01-06 | 2000-07-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-07-07 | 2004-01-06 | 2004-07-07 | $7700.00 | Window Closed / Lapsed |