US5110801A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of acne
Assignee: Individual
•
Filing: 1989-02-22
•
Granted: 1992-05-05
•
Expires: 2009-02-22
Abstract
Abstract Acne is treated by administering to the subject a substance which is effective in blocking glucose entry into sebaceous cells, thereby inhibiting the production of sebum by these cells. Typically, the substance is administered topically and is dissolved or suspended in an appropriate solvent. The preferred substance is phloretin, which can for example, be dissolved in propylene glycol.
Inventors
- 👤 Harry H. Leveen
- 👤 Robert F. Leveen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 22:32
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/7004; A61K31/12; A61K31/33; A61K31/395; A61K31/40; C; C07; C07H; C07H17/00; C07H17/04; C07H17/06; C07H17/065; C07H17/07
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
50 words
A method of treating acne located on the sebaceous cells of skin of a human subject by administering topically to the skin a preparation containing a substance selected from the group consisting of stevioside, isoteviol and steviol which blocks glucose entry into said sebaceous cells thereby inhibiting production of sebum.
Claim 2
Independent Claim
50 words
A method of treating acne located on the sebaceous cells of skin of a human subject by administering topically to the skin a preparation containing a substance selected from the group consisting of stevioside, isoteviol and steviol which blocks glucose entry into said sebaceous cells thereby inhibiting production of sebum.
Claim 3
Dependent Claim
20 words
The method of claim 1 wherein said substance is administered at a rate of at least two applications per day.
Claim 4
Dependent Claim
17 words
The method of claim 1 wherein said preparation contains a carrier which is propylene glycol or glycerol.
Claim 5
Independent Claim
56 words
A method for treating acne, seborrhea, and oily skin which comprises topically administering to a human subject in need of such treatment in an amount effective to prevent entry of glucose into sebaceous cells thereof and to inhibit production of sebum, a substance selected from the group consisting of 3,3'-Diallyl stilbesterol, 3,3'-Di(2-methylallyl) stilbesterol and 3,3'-Di(chloroallyl) stilbesterol.
Claim 6
Independent Claim
56 words
A method for treating acne, seborrhea, and oily skin which comprises topically administering to a human subject in need of such treatment in an amount effective to prevent entry of glucose into sebaceous cells thereof and to inhibit production of sebum, a substance selected from the group consisting of 3,3'-Diallyl stilbesterol, 3,3'-Di(2-methylallyl) stilbesterol and 3,3'-Di(chloroallyl) stilbesterol.
Claim 7
Independent Claim
42 words
A method for treating acne, seborrhea, and oily skin which comprises topically administering to a human subject in need of such treatment, phloretin in an amount effective to prevent entry of glucose into sebaceous cells thereof and to inhibit production of sebum.
Claim 8
Independent Claim
42 words
A method for treating acne, seborrhea, and oily skin which comprises topically administering to a human subject in need of such treatment, phloretin in an amount effective to prevent entry of glucose into sebaceous cells thereof and to inhibit production of sebum.
References Cited (Backward Citations)
US3006810A
Cited
US3006811A
Cited
US3085933A
Cited
US3272702A
Cited
US3523937A
Cited
US4367227A
Cited
US4326055A
Cited
US4272508A
Cited
US4456620A
Cited
EP0071165A1
Cited
US4565806A
Cited
US4684627A
Cited
US4588750A
Cited
US4473551A
Cited
US4507287A
Cited
US4657901A
Cited
US4565863A
Cited
EP0170269A2
Cited
US4814324A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-05-05 | 1995-11-04 | 1996-05-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-05-05 | 1999-11-04 | 2000-05-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-05-05 | 2003-11-04 | 2004-05-05 | $7700.00 | Window Closed / Lapsed |