US5099031A
Expired / Lapsed
US
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Process for the preparation of di- and trialkyl-4'-phthalimidomethylfurocoumarins
Assignee: Bayer AG
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Filing: 1990-10-31
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Granted: 1992-03-24
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Expires: 2010-10-31
Abstract
Abstract Di- and trialkyl-4'-phthalimidomethyl-furocoumarins are prepared by reacting di- or trialkyl-furocoumarins in the presence of an acid and, if appropriate, of a polar solvent with a compound of the formula (I) ##STR1## in which R" represents hydrogen, a second phthalimidomethyl group, C 1 - to C 4 -alkyl or C 1 - to C 6 -acyl, where, when using trialkyl-furocoumarins, R" does not represent hydrogen.
Inventors
- 👤 Gamal Mikhail
- 👤 Hans-Josef Buysch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 03:49
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/02; C07D493/04
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
63 words
A process for the preparation of di- and trialkyl-4'-phthalimidomethyl-furocoumarins, in which a di- or trialkyl-furocoumarine is reacted in the presence of an acid with a compound of the formula ##STR4## in which R" represents hydrogen, a second phthalimidomethyl group, C 1 - to C 4 -alkyl or C 1 - to C 6 -acyl, where, when using trialkyl-furocoumarins, R" does not represent hydrogen.
Claim 2
Dependent Claim
63 words
A process for the preparation of di- and trialkyl-4'-phthalimidomethyl-furocoumarins, in which a di- or trialkyl-furocoumarine is reacted in the presence of an acid with a compound of the formula ##STR4## in which R" represents hydrogen, a second phthalimidomethyl group, C 1 - to C 4 -alkyl or C 1 - to C 6 -acyl, where, when using trialkyl-furocoumarins, R" does not represent hydrogen.
Claim 3
Dependent Claim
35 words
The process of claim 1, in which as oialkylfurocoumarine a 4,5'-dialkylangelicin of the formula (IIa) ##STR5## is employed in which R and R' independently of one another represent a C 1 -C 10 -alkyl radical.
Claim 4
Dependent Claim
36 words
The process of claim 1, in which as trialkylfurocoumarine a 4,5'-8-trialkylpsoralen of the formula (IIb) ##STR6## is employed in which R, R' and R"' independently of one another represent a C 1 -C 10 -alkyl radical.
Claim 5
Dependent Claim
15 words
The process of claim 2, in which R and R' each represent a methyl radical.
Claim 6
Dependent Claim
16 words
The process of claim 3, in which R, R' and R"' each represent a methyl radical.
Claim 7
Dependent Claim
18 words
The process of claim 1, in which bis-N-methylphthalimido ether is employed as the compound of the formula (I).
Claim 8
Dependent Claim
18 words
The process of claim 1, which is carried out at temperatures in the range -10° to +120° C.
Claim 9
Dependent Claim
23 words
The process of claim 1, in which the di- or trialkyl-4'-phthalimidomethyl-furocoumarine obtained is purified by extraction and subsequent concentration of the extracting agent.
Claim 10
Dependent Claim
14 words
The process of claim 8, in which chloroform is used as the extracting agent.
Claim 11
Dependent Claim
16 words
The process of claim 1, which is carried out in the presence of a polar solvent.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-03-24 | 1995-09-23 | 1996-03-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-03-24 | 1999-09-23 | 2000-03-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-03-24 | 2003-09-23 | 2004-03-24 | $7700.00 | Window Closed / Lapsed |