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Method for the simultaneous measurement of nmr signals, in particular for determining flow rates in nuclear spin tomography by means of the multiple slice fourier flow (muff) method

Assignee: Spectrospin AG
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Filing: 1990-08-07
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Granted: 1992-03-03
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Expires: 2010-08-07
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Abstract

Abstract In a method for the simultaneous measurement of spin resonance signals, in particular NMR signals, from layers located at different depths in a test volume, simultaneous excitation of the different layers is effected by a multiple-component rf excitation pulse P n , consisting of n individual components P m with the frequencies ω m , which act selectively on defined layers m of the test volume, in the presence of a layer-selective gradient, the individual components P m having a phase displacement φ m which is varied from one sequence to the next by successive addition of a constant phase increment Δφ m modulo 360 fixed individually for each individual component P m . If phase coding is effected according to the "Fast Fourier Flow Technique" with the aid of a bipolar gradient pulse, then the flow velocity of a medium moving through the test volume can be measured directly in a multi-dimensional Fourier transformation experiment, simultaneous for several flow cross-sections, in a single recording cycle.

Inventors

  • 👤 Jurgen Hennig

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 17:00
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/54; G01R33/56; G01R33/563; G01R33/56308; G01R33/56316; G01R33/483; G01R33/4833; G01R33/4835; G01R33/5635; G01R33/567; G01R33/5673

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 239 words
Method for the simultaneous measurement of spin resonance signals, in particular NMR signals, from layers located at different depths in a test volume comprising the steps of: subjecting the test volume to a homogeneous magnetic field in a Z direction and to successive sequences of pulse-shaped gradient fields; subjecting the test volume to multiple-component rf excitation pulses P n , said excitation pulses being synchronized in time with the gradient fields and having n components P m for exciting, due to a respective frequency W m thereof, a spin resonance of the Larmor frequency W m in a defined layer m of the test volume, a variation in space of the Larmor frequency W m being effected in the Z direction by application of a layer-selective gradient, the individual components P m of the multiple-component rf excitation pulse P n being dephased relative to each other by a phase displacement φ m which is varied from one sequence to a next by successive addition of a constant phase increment Δφ m modulo 360° fixed individually for each individual component P m ; applying a read gradient to the test volume in a direction perpendicular to the Z direction at least for a time of appearance of spin echo signal; measuring the spin echo signal during a complete measuring cycle consisting of n or an integral multiple of n sequences; and subjecting the measured spin echo signal to Fourier transformation.
Claim 2
Dependent Claim 239 words
Method for the simultaneous measurement of spin resonance signals, in particular NMR signals, from layers located at different depths in a test volume comprising the steps of: subjecting the test volume to a homogeneous magnetic field in a Z direction and to successive sequences of pulse-shaped gradient fields; subjecting the test volume to multiple-component rf excitation pulses P n , said excitation pulses being synchronized in time with the gradient fields and having n components P m for exciting, due to a respective frequency W m thereof, a spin resonance of the Larmor frequency W m in a defined layer m of the test volume, a variation in space of the Larmor frequency W m being effected in the Z direction by application of a layer-selective gradient, the individual components P m of the multiple-component rf excitation pulse P n being dephased relative to each other by a phase displacement φ m which is varied from one sequence to a next by successive addition of a constant phase increment Δφ m modulo 360° fixed individually for each individual component P m ; applying a read gradient to the test volume in a direction perpendicular to the Z direction at least for a time of appearance of spin echo signal; measuring the spin echo signal during a complete measuring cycle consisting of n or an integral multiple of n sequences; and subjecting the measured spin echo signal to Fourier transformation.
Claim 3
Dependent Claim 36 words
The method according to claim 1, wherein flow rates of a medium flowing through the test volume are measured in a layer-selective manner by means of a bipolar phase-coding gradient according to the Fourier Flow Method.
Claim 4
Dependent Claim 33 words
The method according to claim 2, further comprising the step of mapping a plurality of flow profiles in order to achieve a qualitative three-dimensional representation of the volume passed by the flowing medium.
Claim 5
Dependent Claim 23 words
The method according to claim 2 wherein the pulse-shaped gradient field sequences are in synchronism with an ECG cycle in a cine mode.
Claim 6
Dependent Claim 23 words
The method according to claim 3 wherein the pulse-shaped gradient field sequences are in synchronism with an ECG cycle in a cine mode.
Claim 7
Dependent Claim 48 words
The method according to claim 1, wherein the sequences are image-recording sequences according to a spin echo 2 DFT method, an observation window of each layer being restricted by an excitation or refocusing pulse, said excitation or refocusing pulse being disk-selective in a direction of a phase gradient.
Claim 8
Dependent Claim 16 words
The method according to claim 6 wherein the measurement is effected in a ECG triggered mode.
Claim 9
Dependent Claim 24 words
The method according to claim 6, wherein phase coding for 2 DFT image reconstruction is effected exclusively through phase modulation of the excitation pulses.
Claim 10
Dependent Claim 24 words
The method according to claim 7, wherein phase coding for 2 DFT image reconstruction is effected exclusively through phase modulation of the excitation pulses.
Claim 11
Dependent Claim 18 words
The method according to claim 1, wherein the sequences are image-recording sequences according to a gradient echo method.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-03-03 1995-09-02 1996-03-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-03-03 1999-09-02 2000-03-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-03-03 2003-09-02 2004-03-03 $7700.00 Window Closed / Lapsed

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