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US5078129A Expired / Lapsed US ⏱️ 0.0 years remaining

Device for stimulating salivation

Assignee: Research Foundation of the State University of New York
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Filing: 1990-03-08
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Granted: 1992-01-07
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Expires: 2010-03-08
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Abstract

Abstract A dispenser for an aqueous sialogogue for the mouth comprises: a) a reservoir for the aqueous sialogogue solution; b) passage means leading from the reservoir to a spray head; and c) a plurality of orifices in the spray head, whereby actuating the spray head causes a plurality of streams to be directed to those regions of the mouth most dry in a reniform pattern. Preferably a metered amount of sialogogue is delivered by an actuating means selected from the group consisting of a hand-activating spray pump, a bulb-activated spray pump or an aerosol propellant. The sialogogue solution comprises: a) from about 2 to about 3 wgt % of food-grade organic acidulant; b) a food-grade sweetener benign to stomic microflora; and c) a saturated calcium phosphate solution, whereby the production of human saliva is promoted in situ without corrosion, infection, or dissolution of human teeth.

Inventors

  • 👤 Israel Kleinberg
  • 👤 Leo M. Sreebny

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 16:09
CPC Classifications
A; A61; A61K; A61K33/00; A61K33/42

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 116 words
In combination, a spray head and an aqueous sialogogue for the alleviation of xerostomia comprising: means for generating a reniform spray form, said reniform spray form coinciding with the location of the salivary glands in the human mouth, said reniform spray generation means consisting of a plurality of orifices in said spray head; said aqueous sialogogue comprising: a) from about 2 to 3 weight-percent of food-grade organic acidulant; b) a food-grade sweetener benign to stomic microflora selected from the group consisting of a sugar, a synthetic sweetener, a reduced sugar-related compound, and mixtures thereof; and c) a saturated calcium phosphate solution, whereby production of human saliva is promoted without corrosion, infection, or dissolution of human teeth.
Claim 2
Dependent Claim 116 words
In combination, a spray head and an aqueous sialogogue for the alleviation of xerostomia comprising: means for generating a reniform spray form, said reniform spray form coinciding with the location of the salivary glands in the human mouth, said reniform spray generation means consisting of a plurality of orifices in said spray head; said aqueous sialogogue comprising: a) from about 2 to 3 weight-percent of food-grade organic acidulant; b) a food-grade sweetener benign to stomic microflora selected from the group consisting of a sugar, a synthetic sweetener, a reduced sugar-related compound, and mixtures thereof; and c) a saturated calcium phosphate solution, whereby production of human saliva is promoted without corrosion, infection, or dissolution of human teeth.
Claim 3
Dependent Claim 33 words
The combination of claim 1, wherein said plurality of orifices consists of an arcuate array of orifices in said spray head from about the 9 o'clock position to about the 3 o'clock position.
Claim 4
Dependent Claim 25 words
The combination of claim 1, wherein said plurality of orifices consists of orifices located at and only at the 10, 12, and 2 o'clock positions.
Claim 5
Dependent Claim 25 words
The combination of claim 1, wherein said plurality of orifices consists of orifices located at and only at the 9, 12, and 3 o'clock positions.
Claim 6
Dependent Claim 26 words
The combination of claim 1, wherein said plurality of orifices consists of orifices located at and only at the 9, 12, 3, and 6 o'clock positions.
Claim 7
Dependent Claim 28 words
The combination of claim 1, wherein said plurality of orifices consists of orifices located at the 10, 10:30, 11, 11:30, 12, 12:30, 1, 1:30, and 2 o'clock positions.
Claim 8
Dependent Claim 20 words
The combination of claim 6, wherein said plurality of orifices further consists of an orifice at the 6 o'clock position.
Claim 9
Dependent Claim 14 words
The combination of claim 1, wherein said plurality of orifices consists of three orifices.
Claim 10
Dependent Claim 15 words
The combination of claim 8, wherein said three orifices are located in a triangular array.
Claim 11
Dependent Claim 20 words
The combination of claim 9, wherein said triangular array consists of one larger upper orifice and two smaller lower orifices.
Claim 12
Dependent Claim 27 words
The combination of claim 1, wherein said spray head has an outline and said plurality of orifices are in an arcuate array approximately parallel to said outline.
Claim 13
Dependent Claim 19 words
The combination of claim 11, wherein said plurality of orifices further consists of an orifice opposite said arcuate array.
Claim 14
Dependent Claim 14 words
The combination of claim 1, wherein said plurality of orifices includes an arcuate orifice.
Claim 15
Dependent Claim 22 words
The combination of claim 13, wherein said plurality of orifices consists of said arcuate orifice and an orifice opposite said arcuate orifice.
Claim 16
Dependent Claim 18 words
The combination of claim 1, wherein said plurality of orifices consists of four orifices in a diamond array.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-01-06 1995-07-08 1996-01-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-01-06 1999-07-08 2000-01-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-01-06 2003-07-08 2004-01-07 $7700.00 Window Closed / Lapsed

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