US5068418A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Separation of lactic acid from fermentation broth with an anionic polymeric absorbent
Assignee: Honeywell UOP LLC
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Filing: 1989-05-08
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Granted: 1991-11-26
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Expires: 2009-05-08
Abstract
Abstract Lactic acid is separated from a fermentation broth by using an adsorbent comprising a water-insoluble macroreticular or gel weakly basic anionic exchange resin possessing tertiary amine or pyridine functional groups or a strongly basic anionic exchange resin possessing quaternary amine fuctional groups. The resins are in sulfate form and have a cross-linked acrylic or styrene resin matrix. Lactic acid is desorbed with water or dilute inorganic acid, e.g., sulfuric. The pH of the feed is maintained below the ionization constant (pKa) of lactic acid to obtain high selectivity.
Inventors
- 👤 Santi Kulprathipanja
- 👤 Anil R. Oroskar
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 21:07
CPC Classifications
C; C07; C07C; C07C51/00; C07C51/42; C07C51/47
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
88 words
A process for separating lactic acid from a fermentation broth mixture containing lactic acid produced by a fermentation process comprising contacting said feed mixture with an anionic polymeric adsorbent comprising a weakly basic anionic exchange resin possessing pyridine functional groups at adsorption conditions selected to selectively adsorb said lactic acid and thereafter recovering said lactic acid from said adsorbent with a desorbent consisting essentially of water or a dilute inorganic acid at desorption conditions, said adsorption conditions including a pH below the ionization constant (pKa) of lactic acid.
Claim 2
Dependent Claim
88 words
A process for separating lactic acid from a fermentation broth mixture containing lactic acid produced by a fermentation process comprising contacting said feed mixture with an anionic polymeric adsorbent comprising a weakly basic anionic exchange resin possessing pyridine functional groups at adsorption conditions selected to selectively adsorb said lactic acid and thereafter recovering said lactic acid from said adsorbent with a desorbent consisting essentially of water or a dilute inorganic acid at desorption conditions, said adsorption conditions including a pH below the ionization constant (pKa) of lactic acid.
Claim 3
Dependent Claim
46 words
The process of claim 1 further characterized in that said adsorption and desorption conditions include a temperature within the range of from about 20° C. to about 200° C. and a pressure within the range of from about atmospheric to about 500 psig (3450 kPa gauge).
Claim 4
Dependent Claim
20 words
The process of claim 1 further characterized in that said desorbent is 0.002 to 0.2N H 2 SO 4 .
Claim 5
Dependent Claim
25 words
The process of claim 1 further characterized in that the pH of said feed mixture is lower than the ionization content (pKa) of lactic acid.
Claim 6
Dependent Claim
33 words
The process of claim 1 further characterized in that said adsorbent comprises a pyridine functional group supported on a matrix selected from the group consisting of crosslinked polystyrene resins and crosslinked acrylic resins.
Claim 7
Dependent Claim
13 words
The process of claim 1 wherein said adsorbent is in the sulfate form.
Claim 8
Dependent Claim
107 words
A process for separating lactic acid from a fermentation broth mixture containing lactic acid produced by a fermentation process comprising contacting said feed mixture with an anionic polymeric adsorbent selected from the group consisting of a weakly basic anionic exchange resin processing tertiary amine functional groups and a strongly basic anionic exchange resin possessing quaternary amine functional groups and mixtures thereof at adsorption conditions selected to selectively adsorb said lactic acid and thereafter recovering said lactic acid from said adsorbent with a desorbent comprising water or a dilute inorganic acid at desorption conditions, said adsorption conditions including a pH below the ionization constant (pKa) of lactic acid.
Claim 9
Dependent Claim
107 words
A process for separating lactic acid from a fermentation broth mixture containing lactic acid produced by a fermentation process comprising contacting said feed mixture with an anionic polymeric adsorbent selected from the group consisting of a weakly basic anionic exchange resin processing tertiary amine functional groups and a strongly basic anionic exchange resin possessing quaternary amine functional groups and mixtures thereof at adsorption conditions selected to selectively adsorb said lactic acid and thereafter recovering said lactic acid from said adsorbent with a desorbent comprising water or a dilute inorganic acid at desorption conditions, said adsorption conditions including a pH below the ionization constant (pKa) of lactic acid.
Claim 10
Dependent Claim
22 words
The process of claim 7 wherein the pH of said feed mixture is lower than the ionization constant (pKa) of lactic acid.
Claim 11
Dependent Claim
13 words
The process of claim 7 wherein said adsorbent is in the sulfate form.
Claim 12
Dependent Claim
23 words
The process of claim 7 wherein said adsorbent comprises a tertiary amine functional group supported on a matrix comprising a crosslinked acrylic resin.
Claim 13
Dependent Claim
23 words
The process of claim 7 wherein said adsorbent comprises a quaternary ammonium functional group supported on a matrix comprising a crosslinked acrylic resin.
Claim 14
Dependent Claim
43 words
The process of claim 7 wherein said adsorption and desorption conditions include a temperature within the range of from about 20° C. to about 200° C. and a pressure within the range of from about atmospheric to about 500 psig (3450 kPa gauge).
Claim 15
Dependent Claim
17 words
The process of claim 7 wherein said desorbent is 0.002 to 0.2N H 2 SO 4 .
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-11-25 | 1995-05-27 | 1995-11-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-11-25 | 1999-05-27 | 1999-11-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-11-25 | 2003-05-27 | 2003-11-26 | $7700.00 | Window Closed / Lapsed |