Patent US5059248A successfully refreshed from Google Patents.
US5059248A
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Stable, fluid, aqueous pigment dispersions for use in film coating tablets and the like
Assignee: WARNER JENKINSON COMPANY Inc A CORP OF NEW YORK
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Filing: 1989-08-11
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Granted: 1991-10-22
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Expires: 2009-08-11
Abstract
Abstract Improved stable, fluid, aqueous dispersion compositions comprise a pigment, an alkali metal, alkaline earth metal or ammonium salt of a linear aliphatic substituted glycine such as a salt of ethylene diamine tetraacetic acid or nitrilo triacetic acid as a stabilizing agent, and water. The dispersion composition may additionally contain a lower alkanol such as methanol and/or a water soluble plasticizer such as propylene glycol. Coating compositions for use as a film coating for tablets and the like contain the above-described stable, fluid, aqueous dispersion composition, a water soluble plasticizer, a film coating resin, and water. The described fluid, aqueous dispersion compositions have been found to remain stable for extended periods exceeding six months.
Inventors
- 👤 Charles A. Signorino
- 👤 Harry Meggos
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 19:35
CPC Classifications
C; C09; C09D; C09D17/00; C09D17/001; A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; C09B; C09B67/00; C09B67/006; Y; Y10; Y10S; Y10S516/00; Y10S516/01; Y10S516/02; Y10S516/06; Y10S516/07
Claims Analysis
Total Claims: 34
Claim 1
Independent Claim
85 words
A stable, fluid, aqueous dispersion composition consisting essentially of from approximately 25 to 40 wt. % of a pigment selected from the group consisting of an FD&C lake, a D&C lake and ceramine or a combination of such lakes with titanium dioxide or iron oxide, a stabilizing agent selected from the group consisting of an alkali metal, alkaline earth metal or ammonium salt of a linear aliphatic substituted glycine, said stabilizing agent constituting from approximately 0.5 to 3.5 wt. % of said pigment, and water.
Claim 2
Dependent Claim
85 words
A stable, fluid, aqueous dispersion composition consisting essentially of from approximately 25 to 40 wt. % of a pigment selected from the group consisting of an FD&C lake, a D&C lake and ceramine or a combination of such lakes with titanium dioxide or iron oxide, a stabilizing agent selected from the group consisting of an alkali metal, alkaline earth metal or ammonium salt of a linear aliphatic substituted glycine, said stabilizing agent constituting from approximately 0.5 to 3.5 wt. % of said pigment, and water.
Claim 3
Dependent Claim
55 words
A stable, fluid, aqueous dispersion composition as set forth in claim 1 wherein said stabilizing agent is selected from the group consisting of the alkali metal, alkaline earth metal and ammonium salts of ethylene diamine tetraacetic acid, nitrilo triacetic acid, diethylene triamine pentaacetic acid, hydroxyethylene diamine triacetic acid, dihydroxyethyl glycine, iminodiacetic acid and ethanol diglycine.
Claim 4
Dependent Claim
25 words
A stable, fluid, aqueous dispersion composition as set forth in claim 2 wherein said stabilizing agent is the disodium salt of ethylene diamine tetraacetic acid.
Claim 5
Dependent Claim
25 words
A stable, fluid, aqueous dispersion composition as set forth in claim 2 wherein said stabilizing agent is the tetrasodium salt of ethylene diamine tetraacetic acid.
Claim 6
Dependent Claim
26 words
A stable, fluid, aqueous dispersion composition as set forth in claim 2 wherein said stabilizing agent is the calcium disodium salt of ethylene diamine tetraacetic acid.
Claim 7
Dependent Claim
24 words
A stable, fluid, aqueous dispersion composition as set forth in claim 2 wherein said stabilizing agent is the trisodium salt of nitrilo triaacetic acid.
Claim 8
Dependent Claim
25 words
A stable, fluid, aqueous dispersion composition as set forth in claim 2 wherein said stabilizing agent is the pentasodium salt of diethylene triamine pentaacetic acid.
Claim 9
Dependent Claim
23 words
A stable, fluid, aqueous dispersion composition as set forth in claim 2 wherein said stabilizing agent is the disodium salt of ethanol diglycine.
Claim 10
Dependent Claim
24 words
A stable, fluid, aqueous dispersion composition as set forth in claim 2 wherein said stabilizing agent is the disodium salt of imino diacetic acid.
Claim 11
Dependent Claim
32 words
A stable, fluid, aqueous dispersion composition as set forth in claim 1 wherein said pigment is a combination of an FD&C lake or a D&C lake and titanium dioxide or iron oxide.
Claim 12
Dependent Claim
29 words
A stable, fluid, aqueous dispersion composition as set forth in claim 1 wherein said stabilizing agent constitutes approximately 1.5 to 2.5 wt. % of said pigment in the composition.
Claim 13
Dependent Claim
104 words
A stable, fluid, aqueous dispersion composition consisting essentially of from approximately 25 to 40 wt. % of a pigment selected from the group consisting of an FD&C lake, a D&C lake and carmine or a combination of one of such lakes with titanium dioxide or iron oxide, a stabilizing agent selected from the group consisting of an alkali metal, alkaline earth metal or ammonium salt of ethylene diamine tetraacetic acid, diethylene triamine pentaacetic acid and dihydroxyethyl glycine, said stabilizing agent constituting from approximately 0.5 to 3.5 wt. % of said pigment, from approximately 25 to 40% wt. % of a lower alkanol and water.
Claim 14
Dependent Claim
104 words
A stable, fluid, aqueous dispersion composition consisting essentially of from approximately 25 to 40 wt. % of a pigment selected from the group consisting of an FD&C lake, a D&C lake and carmine or a combination of one of such lakes with titanium dioxide or iron oxide, a stabilizing agent selected from the group consisting of an alkali metal, alkaline earth metal or ammonium salt of ethylene diamine tetraacetic acid, diethylene triamine pentaacetic acid and dihydroxyethyl glycine, said stabilizing agent constituting from approximately 0.5 to 3.5 wt. % of said pigment, from approximately 25 to 40% wt. % of a lower alkanol and water.
Claim 15
Dependent Claim
18 words
A stable, fluid, aqueous dispersion composition as set forth in claim 12 wherein said lower alkanol is methanol.
Claim 16
Dependent Claim
18 words
A stable, fluid, aqueous dispersion composition as set forth in claim 12 wherein said lower alkanol is ethanol.
Claim 17
Dependent Claim
25 words
A stable, fluid, aqueous dispersion composition as set forth in claim 12 wherein said stabilizing agent is the disodium salt of ethylene diamine tetraacetic acid.
Claim 18
Dependent Claim
25 words
A stable, fluid, aqueous dispersion composition as set forth in claim 12 wherein said stabilizing agent is the tetrasodium salt of ethylene diamine tetraacetic acid.
Claim 19
Dependent Claim
26 words
A stable, fluid, aqueous dispersion composition as set forth in claim 12 wherein said stabilizing agent is the calcium disodium salt of ethylene diamine tetraacetic acid.
Claim 20
Dependent Claim
32 words
A stable, fluid, aqueous dispersion composition as set forth in claim 15 wherein said pigment is a combination of an FD&C lake or a D&C lake and titanium dioxide or iron oxide.
Claim 21
Dependent Claim
20 words
A stable, fluid, aqueous dispersion composition comprising the stable, fluid, aqueous dispersion of claim 15 and a water soluble plasticizer.
Claim 22
Dependent Claim
30 words
A stable, fluid, aqueous dispersion composition as set forth in claim 19 wherein said water soluble plasticizer is selected from the group consisting of glycerin, propylene glycol and polyethylene glycol.
Claim 23
Dependent Claim
30 words
A coating composition for use as a film coating for tablets comprising the stable, fluid, aqueous dispersion of claim 1, a water soluble plasticizer, a film coating resin, and water.
Claim 24
Dependent Claim
36 words
A coating composition as set forth in claim 21 wherein said film coating resin is selected from the group consisting of methyl cellulose, hydroxypropylmethyl cellulose, hydroxypropyl cellulose, ethyl cellulose, cellulose acetate phthalate, shellac and polyvinyl pyrrolidone.
Claim 25
Dependent Claim
17 words
A coating composition as set forth in claim 21 wherein said film coating resin is hydroxypropylmethyl cellulose.
Claim 26
Dependent Claim
27 words
A coating composition as set forth in claim 21 wherein said water soluble plasticizer is selected from the group consisting of glycerin, propylene glycol and polyethylene glycol.
Claim 27
Dependent Claim
29 words
A coated tablet having as the coating a thin film comprising the stable, fluid, aqueous dispersion of claim 1, a water soluble plasticizer, a film coating resin, and water.
Claim 28
Dependent Claim
17 words
A coated tablet as set forth in claim 25 wherein said film coating resin is hydroxypropylmethyl cellulose.
Claim 29
Dependent Claim
28 words
A coated tablet as set forth in claim 25 wherein the stabilizing agent in said stable, fluid, aqueous dispersion is the disodium salt of ethylene diamine tetraacetic acid.
Claim 30
Dependent Claim
28 words
A coated tablet as set forth in claim 25 wherein the stabilizing agent in said stable, fluid, aqueous dispersion is the tetrasodium salt of ethylene diamine tetraacetic acid.
Claim 31
Dependent Claim
29 words
A coated tablet as set forth in claim 25 wherein the stabilizing agent in said stable, fluid, aqueous dispersion is the calcium disodium salt of ethylene diamine tetraacetic acid.
Claim 32
Dependent Claim
34 words
A coated tablet as set forth in claim 25 wherein the pigment in said stable, fluid, aqueous dispersion is an F D & C lake, D & C lake or carmine or mixtures thereof.
Claim 33
Dependent Claim
33 words
A coated tablet as set forth in claim 25 wherein the stabilizing agent in said stable, fluid, aqueous dispersion constitutes from approximately 0.5 to 3.5 wt. % of the pigment in said dispersion.
Claim 34
Dependent Claim
28 words
A coated tablet as set forth in claim 25 wherein the pigment in said stable, fluid, aqueous dispersion constitutes approximately 25 to 40 wt. % of said dispersion.
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1994-10-21 | 1995-04-22 | 1995-10-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-10-21 | 1999-04-22 | 1999-10-22 | $3760.00 | Window Closed / Lapsed |
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