Patent US5041370A successfully refreshed from Google Patents.
US5041370A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pseudorabies virus (PRV) gene, host cell, method for detecting animals infected with pseudorabies virus, and kit therefor
Assignee: Pharmacia and Upjohn Co
•
Filing: 1986-04-17
•
Granted: 1991-08-20
•
Expires: 2006-04-17
Abstract
Abstract The present invention provides a recombinant DNA sequence encoding the pseudorabies virus (PRV) glycoprotein gX, host cells transformed by said DNA sequence, the gX polypeptide, and methods and kits for detecting animals infected with PRV.
Inventors
- 👤 deceased Hamdy
- 👤 Heir By Heide M Hamdy
- 👤 Roger J. Brideau
- 👤 Leonard E. Post
- 👤 Thomas J. Rea
- 👤 James G. Timmins
- 👤 Carmine C. Marchioli
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 12:53
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; A; A61; A61K; A61K39/00; C12; C12N; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16711; C12N2710/16722; Y; Y10; Y10S; Y10S530/00; Y10S530/82; Y10S530/826; Y10S530/827; Y10S530/829
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
29 words
A host cell transformed with a recombinant sequence of DNA basepairs comprising a sequence of DNA basepairs coding for the pseudorabies virus (PRV) glycoprotein gX or immunological fragments thereof.
Claim 2
Dependent Claim
29 words
A host cell transformed with a recombinant sequence of DNA basepairs comprising a sequence of DNA basepairs coding for the pseudorabies virus (PRV) glycoprotein gX or immunological fragments thereof.
Claim 3
Dependent Claim
50 words
A host cell of claim 1 wherein the sequence of DNA basepairs coding for the PRV glycoprotein gX or immunological fragment thereof has the following formula: or a fragment thereof encoding an immunological fragment of glycoprotein gX or a functional equivalent of said sequence of DNA basepairs or fragment thereof.
Claim 4
Dependent Claim
11 words
A host cell of claim 2 which is a bacterial microorganism.
Claim 5
Dependent Claim
10 words
A host cell of claim 3 which is E. coli.
Claim 6
Dependent Claim
9 words
A host cell of claim 2 which is yeast.
Claim 7
Dependent Claim
11 words
A host cell of claim 2 which is an animal cell.
Claim 8
Dependent Claim
11 words
A host cell of claim 6 which is a mammalian cell.
Claim 9
Dependent Claim
63 words
In an immunological diagnostic method for detecting animals infected with pseudorabies virus comprising contacting serum from an animal of interest with antigen from pseudorabies virus and then detecting any antigen/antibody reaction, the improvement which comprises using as said antigen, pseudorabies virus glycoprotein gX antigen or immunological fragment(s) thereof, produced by a host cell of claim 1, and free from other pseudorabies virus antigens.
Claim 10
Dependent Claim
58 words
A diagnostic kit for performing the method according to claim 8, comprising pseudorabies virus glycoprotein gX or immunological fragment(s) thereof produced by a host cell transformed with a recombinant sequence of DNA basepairs comprising a sequence of DNA basepairs coding for the pseudorabies virus glycoprotein gX or immunological fragment(s) thereof and being free from other pseudorabies virus antigens.
Claim 11
Dependent Claim
21 words
A recombinant sequence of DNA basepairs comprising DNA basepairs encoding the pseudorabies virus (PRV) glycoprotein gX or an immunological fragment thereof.
Claim 12
Dependent Claim
21 words
A recombinant sequence of DNA basepairs comprising DNA basepairs encoding the pseudorabies virus (PRV) glycoprotein gX or an immunological fragment thereof.
Claim 13
Dependent Claim
22 words
A recombinant sequence of DNA basepairs of claim 10 wherein the DNA basepairs encoding the PRV glycoprotein gX has the formula: ##STR3##
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-08-19 | 1995-02-18 | 1995-08-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-08-19 | 1999-02-18 | 1999-08-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-08-19 | 2003-02-18 | 2003-08-20 | $7700.00 | Window Closed / Lapsed |