Patent US4367462A successfully refreshed from Google Patents.
Patent US5039459A successfully refreshed from Google Patents.
US5039459A
Expired / Lapsed
US
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Method of forming shaped hydrogel articles including contact lenses
Assignee: Johnson and Johnson Vision Care Inc
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Filing: 1989-12-15
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Granted: 1991-08-13
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Expires: 2009-12-15
Abstract
Abstract Shaped hydrogel articles such as soft contact lenses are prepared by (1) molding or casting a polymerization mixture comprising: (a) a monomer mixture comprising a major proportion of a hydrophilic (meth)acrylate ester such as 2-hydroxyethyl methacrylate, an alkyl (meth)acrylate wherein the alkyl group contains at least four carbon atoms, and a cross-linking monomer; and (b) a water-displaceable diluent, wherein said diluent has a viscosity of at least 100 MPa Sec at 30 DEG C., and wherein said diluent consists essentially of a boric acid ester of certain dihydric alcohols, said dihydric alcohols having Hansen polar (wp) and Hansen hydrogen bonding (wh) cohesion parameters falling within the area of a circle defined as having a center at wh=20.5, wp=13, and a radius of 8.5, to produce a shaped gel of a copolymer of said monomers and said diluent, and (2) thereafter replacing said diluent with water.
Inventors
- 👤 Ture Kindt-Larsen
- 👤 John C. Heaton
- 👤 Edmund C. Rastrelli
- 👤 Gregory A. Hill
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 22:21
CPC Classifications
C; C08; C08F; C08F212/00; G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; B; B29; B29D; B29D11/00; B29D11/00009; B29D11/00038; B29K; B29K2033/00; B29K2033/04; B29K2033/08; B29K2033/12; B29K2105/00; B29K2105/0002; B29K2707/00; B29K2707/02; B29K2995/00; B29K2995/0037; B29K2995/0092; Y; Y10; Y10S; Y10S524/00; Y10S524/916
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
149 words
Process for producing shaped hydrogel articles which comprises the steps of: (1) molding or casting a polymerization mixture comprising: (a) a monomer mixture comprising a major proportion of a hydrophilic (meth)acrylate ester monomer, an alkyl (meth)acrylate wherein the alkyl group contains at least four carbon atoms, and a cross-linking monomer; and (b) a water-displaceable diluent, wherein said diluent has a viscosity of at least 100 MPa Sec at 30° C., and wherein said diluent consists essentially of a boric acid ester of certain dihydric alcohols, said dihydric alcohols having Hansen polar (w p ) and Hansen hydrogen bonding (w h ) cohesion parameters falling within the area of a circle defined as having a center at w h =20.5, w p =13, and a radius of 8.5, to produce a shaped gel of a copolymer of said monomers and said diluent, and (2) thereafter replacing said diluent with water.
Claim 2
Dependent Claim
149 words
Process for producing shaped hydrogel articles which comprises the steps of: (1) molding or casting a polymerization mixture comprising: (a) a monomer mixture comprising a major proportion of a hydrophilic (meth)acrylate ester monomer, an alkyl (meth)acrylate wherein the alkyl group contains at least four carbon atoms, and a cross-linking monomer; and (b) a water-displaceable diluent, wherein said diluent has a viscosity of at least 100 MPa Sec at 30° C., and wherein said diluent consists essentially of a boric acid ester of certain dihydric alcohols, said dihydric alcohols having Hansen polar (w p ) and Hansen hydrogen bonding (w h ) cohesion parameters falling within the area of a circle defined as having a center at w h =20.5, w p =13, and a radius of 8.5, to produce a shaped gel of a copolymer of said monomers and said diluent, and (2) thereafter replacing said diluent with water.
Claim 3
Dependent Claim
14 words
The process of claim 1 wherein the said hydrophilic monomer is a hydroxyalkyl (meth)acrylate.
Claim 4
Dependent Claim
12 words
The process of claim 2 wherein the hydroxyalkyl (meth)acrylate is 2-hydroxyethyl methacrylate.
Claim 5
Dependent Claim
21 words
The process of claim 1 wherein said alkyl (meth)acrylate is n-hexyl methacrylate, n-octyl methacrylate, 2-ethylhexyl methacrylate, decyl methacrylate, or n-dodecyl methacrylate.
Claim 6
Dependent Claim
11 words
The process of claim 1 wherein said dihydric alcohol is 1,4-butanediol.
Claim 7
Dependent Claim
12 words
The process of claim 1 wherein said dihydric alcohol is diethylene glycol.
Claim 8
Dependent Claim
12 words
The process of claim 1 wherein the monomer mixture contains methacrylic acid.
Claim 9
Dependent Claim
14 words
The process of claim 1 wherein the shaped hydrogel article is a contact lens.
Claim 10
Dependent Claim
147 words
Process for producing contact lenses which comprises the steps of: (1) molding or casting a polymerization mixture comprising: (a) a monomer mixture comprising a major proportion of a hydrophilic (meth)acrylate ester, a cross-linking monomer, and an alkyl (meth)acrylate wherein the alkyl group contains at least four carbon atoms; and (b) a water-displaceable diluent, wherein said diluent has a viscosity of at least 100 MPa Sec at 30° C., and wherein said diluent consists essentially of a boric acid ester of certain dihydric alcohols, said dihydric alcohols having Hansen polar (w p ) and Hansen hydrogen bonding (w h ) cohesion parameters falling within the area of a circle defined as having a center at w h =20.5, w p =13, and a radius of 8.5, to produce a shaped gel of a copolymer of said monomers and said diluent, and (2) thereafter replacing said diluent with water.
Claim 11
Dependent Claim
147 words
Process for producing contact lenses which comprises the steps of: (1) molding or casting a polymerization mixture comprising: (a) a monomer mixture comprising a major proportion of a hydrophilic (meth)acrylate ester, a cross-linking monomer, and an alkyl (meth)acrylate wherein the alkyl group contains at least four carbon atoms; and (b) a water-displaceable diluent, wherein said diluent has a viscosity of at least 100 MPa Sec at 30° C., and wherein said diluent consists essentially of a boric acid ester of certain dihydric alcohols, said dihydric alcohols having Hansen polar (w p ) and Hansen hydrogen bonding (w h ) cohesion parameters falling within the area of a circle defined as having a center at w h =20.5, w p =13, and a radius of 8.5, to produce a shaped gel of a copolymer of said monomers and said diluent, and (2) thereafter replacing said diluent with water.
Claim 12
Dependent Claim
14 words
The process of claim 9 wherein the said hydrophilic monomer is a hydroxyalkyl (meth)acrylate.
Claim 13
Dependent Claim
12 words
The process of claim 10 wherein the hydroxyalkyl (meth)acrylate is 2-hydroxyethyl methacrylate.
Claim 14
Dependent Claim
20 words
The process of claim 9 wherein said diluent has a viscosity of at least 500 MPa Sec at 30° C.
Claim 15
Dependent Claim
19 words
The process of claim 9 wherein said alkyl (meth)acrylate is n-hexyl methacrylate, n-octyl methacrylate, 2-ethylhexyl methacrylate, or n-dodecyl methacrylate.
Claim 16
Dependent Claim
11 words
The process of claim 9 wherein said dihydric alcohol is 1,4-butanediol.
Claim 17
Dependent Claim
12 words
The process of claim 9 wherein said dihydric alcohol is diethylene glycol.
Claim 18
Dependent Claim
12 words
The process of claim 9 wherein the monomer mixture contains methacrylic acid.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-08-12 | 1995-02-11 | 1995-08-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-08-12 | 1999-02-11 | 1999-08-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-08-12 | 2003-02-11 | 2003-08-13 | $7700.00 | Window Closed / Lapsed |