US5026839A
Expired / Lapsed
US
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DNA encoding a basic fibroblast growth factor
Assignee: Amgen Boulder Inc
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Filing: 1990-04-05
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Granted: 1991-06-25
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Expires: 2010-04-05
Abstract
Abstract An isolated DNA sequence encoding an angiogenic factor protein consisting of a single-polypeptide-chain protein having at least one active site possessing mitotic and chemotactic activity and the ability to stimulate protease synthesis, wherein said protein consists of the amino acid sequence: ##STR1## In a preferred embodiment, the DNA sequence encodes basic fibroblast growth factor (bFGF).
Inventors
- 👤 David A. Moscatelli
- 👤 Daniel B. Rifkin
- 👤 Andreas Sommer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-10 01:05
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/11; C12N15/62; C12N15/625; C07; C07K; C07K14/00; C07K14/435; C07K14/475; C07K14/515; C12N15/63; C12N15/70; A; A61; A61K; A61K38/00; C07K2319/00; C07K2319/01; C07K2319/035; C07K2319/70; C07K2319/74; C07K2319/75
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
42 words
An isolated DNA sequence encoding an angiogenic factor protein consisting of a single-polypeptide-chain protein having at least one active site possessing mitotic and chemotactic activity and the ability to stimulate protease synthesis, wherein said protein consists of the amino acid sequence: ##STR27##
Claim 2
Dependent Claim
42 words
An isolated DNA sequence encoding an angiogenic factor protein consisting of a single-polypeptide-chain protein having at least one active site possessing mitotic and chemotactic activity and the ability to stimulate protease synthesis, wherein said protein consists of the amino acid sequence: ##STR27##
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-06-24 | 1994-12-24 | 1995-06-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-06-24 | 1998-12-24 | 1999-06-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-06-24 | 2002-12-24 | 2003-06-25 | $7700.00 | Window Closed / Lapsed |