US5013714A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Viscoelastic solution
Assignee: Individual
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Filing: 1988-12-15
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Granted: 1991-05-07
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Expires: 2008-12-15
Abstract
Abstract Viscoelastic solution including a buffered solution, 0.01-8% chondroitin sulfate, 0.1-8% hydroxypropyl methylcellulose, pH adjusted to 6.0-8.0 at a osmolality between 200-400 mOsmol/L. The buffered solution can be HEPES buffered minimum essential media (MEM), phosphate buffer saline (PBS), buffered balanced salt solution, or TC199. A cell growth factor or cell growth supplement is included in the solution.
Inventors
- 👤 Richard L. Lindstrom
- 👤 Debra Skelnik
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 14:07
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/28; A01; A01N; A01N1/00; A01N1/10; A01N1/12; A01N1/122; A01N1/126; A61K38/18; A61K38/1808
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
35 words
A viscoelastic solution comprising: a. a buffered balanced salt solution; b. hydroxypropyl methylcellulose; c. chondroitin sulfate; and, e. Epidermal Growth Factor (EGF); the solution having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
Claim 2
Dependent Claim
35 words
A viscoelastic solution comprising: a. a buffered balanced salt solution; b. hydroxypropyl methylcellulose; c. chondroitin sulfate; and, e. Epidermal Growth Factor (EGF); the solution having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
Claim 3
Dependent Claim
41 words
A viscoelastic solution comprising: a. a buffered balanced salt solution; b. 2.75% hydroxypropyl methylcellulose; c. 0.5% chondroitin sulfate; and, d. Epidermal Growth Factor (EGF) (range 0.1 ng/ml-100 mg/ml); the composition having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
Claim 4
Dependent Claim
41 words
A viscoelastic solution comprising: a. a buffered balanced salt solution; b. 2.75% hydroxypropyl methylcellulose; c. 0.5% chondroitin sulfate; and, d. Epidermal Growth Factor (EGF) (range 0.1 ng/ml-100 mg/ml); the composition having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
Claim 5
Dependent Claim
36 words
A viscoelastic solution comprising: a. a buffered balanced salt solution; b. hydroxypropyl methylcellulose; c. chondroitin sulfate; e. Epidermal Growth Factor; and, f. insulin; the composition having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
Claim 6
Dependent Claim
36 words
A viscoelastic solution comprising: a. a buffered balanced salt solution; b. hydroxypropyl methylcellulose; c. chondroitin sulfate; e. Epidermal Growth Factor; and, f. insulin; the composition having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
Claim 7
Dependent Claim
33 words
A viscoelastic solution comprising: a. a buffered balanced salt solution; b. 2.75% hydroxypropyl methylcellulose; c. 0.5% chondroitin sulfate; d. Epidermal Growth Factor (EGF) (range 0.1 ng/ml-100 mg; and, e. insulin 0.1 ug/ml-10 mg/ml.
Claim 8
Dependent Claim
33 words
A viscoelastic solution comprising: a. a buffered balanced salt solution; b. 2.75% hydroxypropyl methylcellulose; c. 0.5% chondroitin sulfate; d. Epidermal Growth Factor (EGF) (range 0.1 ng/ml-100 mg; and, e. insulin 0.1 ug/ml-10 mg/ml.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-05-06 | 1994-11-05 | 1995-05-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-05-06 | 1998-11-05 | 1999-05-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-05-06 | 2002-11-05 | 2003-05-07 | $7700.00 | Window Closed / Lapsed |