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US5010167A
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Poly(amide-and imide-co-anhydride) for biological application
Assignee: Massachusetts Institute of Technology
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Filing: 1989-03-31
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Granted: 1991-04-23
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Expires: 2009-03-31
Abstract
Abstract Biocompatible, biodegradable poly(amide- and imide-co-anhydride)s are described which are useful for biological applications such as biodegradable controlled release devices for drug delivery, site-specific drug carriers, matrices for cell attachment, and for bioabsorbable sutures.
Inventors
- 👤 Eyal Ron
- 👤 Andrea Staubli
- 👤 Robert S. Langer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 12:31
CPC Classifications
C; C08; C08G; C08G69/00; C08G69/02; C08G69/08; C08G69/10; A; A61; A61K; A61K47/00; A61K47/30; A61K47/34; A61L; A61L17/00; A61L17/06; A61L17/10; C07; C07K; C07K17/00; C07K17/02; C07K17/08; A61K38/00
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
55 words
A biocompatible, biodegradable polymer produced from monomers selected from the group consisting of ##STR4## wherein X is an aliphatic or aromatic group of C 1 -C 20 ; Y is a C-terminus peptide or proline, and Z is a C-terminus peptide or amino acid, and having a weight average molecular weight of greater than 10,000.
Claim 2
Dependent Claim
55 words
A biocompatible, biodegradable polymer produced from monomers selected from the group consisting of ##STR4## wherein X is an aliphatic or aromatic group of C 1 -C 20 ; Y is a C-terminus peptide or proline, and Z is a C-terminus peptide or amino acid, and having a weight average molecular weight of greater than 10,000.
Claim 3
Dependent Claim
24 words
The polymer of claim 1 wherein the monomer is selected from the group consisting of N-succinyl-proline, N-succinyl-peptide, N-trimellitylimido-amino acid, N-trimellitylimido-peptide, N,N-pyromellityldiimido-amino acid, and N,N-pyromellityldiimido-peptide.
Claim 4
Dependent Claim
17 words
A device formed of the polymer of claim 1 for controlled delivery of a biologically active substance.
Claim 5
Dependent Claim
9 words
A bioabsorble suture of the polymer of claim 1.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-04-22 | 1994-10-22 | 1995-04-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-04-22 | 1998-10-22 | 1999-04-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-04-22 | 2002-10-22 | 2003-04-23 | $7700.00 | Window Closed / Lapsed |