Patent US5006536A successfully refreshed from Google Patents.
US5006536A
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Thienobenzoxepins and analgesic compositions thereof
Assignee: Aventis Pharmaceuticals Inc
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Filing: 1989-12-26
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Granted: 1991-04-09
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Expires: 2009-12-26
Abstract
Abstract Novel thienobenzoxepins and naphthothiophenes, intermediates and processes for the preparation thereof, and methods of alleviating pain utilizing compounds or compositions thereof are disclosed.
Inventors
- 👤 Richard C. Effland
- 👤 David G. Wettlaufer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 03:46
CPC Classifications
C; C07; C07D; C07D409/00; C07D409/02; C07D409/04; A; A61; A61P; A61P25/00; A61P25/04; C07D409/06; C07D495/00; C07D495/02; C07D495/04
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
45 words
A compound of the formula ##STR6## wherein R is loweralkyl or arylloweralkyl; X and Y are independently hydrogen, loweralkyl, halogen, loweralkoxy, or trifluoromethyl; W is CH 2 , CHOH, or C═O; and n is 1 or 2; an optical isomer or pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
45 words
A compound of the formula ##STR6## wherein R is loweralkyl or arylloweralkyl; X and Y are independently hydrogen, loweralkyl, halogen, loweralkoxy, or trifluoromethyl; W is CH 2 , CHOH, or C═O; and n is 1 or 2; an optical isomer or pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
14 words
A compound according to claim 1 wherein W is C═O and n is 2.
Claim 4
Dependent Claim
8 words
The compound of claim 2 which is 4-(1-methyl-4-piperidinyl)thieno[3,2-c][1]benzoxepin-10(4H)-one.
Claim 5
Dependent Claim
8 words
The compound of claim 2 which is 7-fluoro-4-(1-methyl-4-piperidinyl)thieno[3,2-c][1]benzoxepin-10(4H)-one.
Claim 6
Dependent Claim
29 words
A method of alleviating pain in a mammal by administering to a mammal in need of pain alleviation a pain alleviating effective amount of a compound of claim 1.
Claim 7
Dependent Claim
20 words
A composition comprising a pain alleviating effective amount of a compound of claim 1 and a pharmaceutically acceptable adjuvant therefor.
References Cited (Backward Citations)
US4312868A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-04-08 | 1994-10-08 | 1995-04-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-04-08 | 1998-10-08 | 1999-04-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-04-08 | 2002-10-08 | 2003-04-09 | $7700.00 | Window Closed / Lapsed |